Cysteine residues in CUB-1 domain are critical for ADAMTS13 secretion and stability

Thrombosis and Haemostasis

Volumn 105, Issue 1, 2011, Pages 21-30

  Zhou, Zhou ^a   Yeh, Hui Chun ^a   Jing, Hua ^b   Wang, Christina ^a   Tao, Zhenyin ^a   Choi, Huiwan ^a   Aboulfatova, Khatira ^a   Li, Renhao ^b   Dong, Jing Fei ^a,c  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

ADAMTS13; Biosynthesis; CUB domains; Cysteine; Stability; TTP

Indexed keywords

MUTANT PROTEIN; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME RELEASE; ENZYME STABILITY; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION;

ADAM PROTEINS; ANIMALS; CELL LINE; CYSTEINE; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; PEPTIDE HYDROLASES; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; VON WILLEBRAND FACTOR;

EID: 78651108477     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH10-07-0446     Document Type: Article

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