메뉴 건너뛰기




Volumn 108, Issue 1, 2011, Pages 319-324

Therapeutically targeting cyclin D1 in primary tumors arising from loss of Ini1

Author keywords

Atypical teratoid rhabdoid tumors; Genetically engineered mouse model; hSNF5; SMARCB1

Indexed keywords

CYCLIN D1; FLAVOPIRIDOL;

EID: 78651106536     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0913297108     Document Type: Article
Times cited : (36)

References (21)
  • 1
    • 33646104935 scopus 로고    scopus 로고
    • Molecular genetics of atypical teratoid/rhabdoid tumor
    • Biegel JA (2006) Molecular genetics of atypical teratoid/rhabdoid tumor. Neurosurg Focus 20:E11.
    • (2006) Neurosurg Focus , vol.20
    • Biegel, J.A.1
  • 2
    • 20144383987 scopus 로고    scopus 로고
    • Atypical teratoid/rhabdoid tumors (ATRT): Improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy
    • Tekautz TM, et al. (2005) Atypical teratoid/rhabdoid tumors (ATRT): Improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy. J Clin Oncol 23:1491-1499.
    • (2005) J Clin Oncol , vol.23 , pp. 1491-1499
    • Tekautz, T.M.1
  • 3
    • 2642647094 scopus 로고    scopus 로고
    • Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
    • Versteege I, et al. (1998) Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 394:203-206.
    • (1998) Nature , vol.394 , pp. 203-206
    • Versteege, I.1
  • 4
    • 2042432488 scopus 로고    scopus 로고
    • Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers
    • Sévenet N, et al. (1999) Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers. Am J Hum Genet 65:1342-1348.
    • (1999) Am J Hum Genet , vol.65 , pp. 1342-1348
    • Sévenet, N.1
  • 5
    • 28544450604 scopus 로고    scopus 로고
    • Loss of the hSNF5 gene concomitantly inactivates p21CIP/WAF1 and p16INK4a activity associated with replicative senescence in A204 rhabdoid tumor cells
    • Chai J, Charboneau AL, Betz BL, Weissman BE (2005) Loss of the hSNF5 gene concomitantly inactivates p21CIP/WAF1 and p16INK4a activity associated with replicative senescence in A204 rhabdoid tumor cells. Cancer Res 65:10192-10198.
    • (2005) Cancer Res , vol.65 , pp. 10192-10198
    • Chai, J.1    Charboneau, A.L.2    Betz, B.L.3    Weissman, B.E.4
  • 6
    • 0036315846 scopus 로고    scopus 로고
    • Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5
    • Zhang ZK, et al. (2002) Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5. Mol Cell Biol 22:5975-5988.
    • (2002) Mol Cell Biol , vol.22 , pp. 5975-5988
    • Zhang, Z.K.1
  • 7
    • 24744453298 scopus 로고    scopus 로고
    • Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss
    • Tsikitis M, Zhang Z, Edelman W, Zagzag D, Kalpana GV (2005) Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss. Proc Natl Acad Sci USA 102:12129-12134.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12129-12134
    • Tsikitis, M.1    Zhang, Z.2    Edelman, W.3    Zagzag, D.4    Kalpana, G.V.5
  • 8
    • 22144439395 scopus 로고    scopus 로고
    • Cyclin D1 is overexpressed in atypical teratoid/rhabdoid tumor with hSNF5/INI1 gene inactivation
    • Fujisawa H, Misaki K, Takabatake Y, Hasegawa M, Yamashita J (2005) Cyclin D1 is overexpressed in atypical teratoid/rhabdoid tumor with hSNF5/INI1 gene inactivation. J Neurooncol 73:117-124.
    • (2005) J Neurooncol , vol.73 , pp. 117-124
    • Fujisawa, H.1    Misaki, K.2    Takabatake, Y.3    Hasegawa, M.4    Yamashita, J.5
  • 9
    • 53549095222 scopus 로고    scopus 로고
    • Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability
    • McKenna ES, et al. (2008) Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability. Mol Cell Biol 28:6223-6233.
    • (2008) Mol Cell Biol , vol.28 , pp. 6223-6233
    • McKenna, E.S.1
  • 10
    • 32244438873 scopus 로고    scopus 로고
    • Targeting cyclin D1, a downstream effector of INI1/ hSNF5, in rhabdoid tumors
    • Alarcon-Vargas D, et al. (2006) Targeting cyclin D1, a downstream effector of INI1/ hSNF5, in rhabdoid tumors. Oncogene 25:722-734.
    • (2006) Oncogene , vol.25 , pp. 722-734
    • Alarcon-Vargas, D.1
  • 11
    • 38949163697 scopus 로고    scopus 로고
    • Rhabdoid tumor growth is inhibited by flavopiridol
    • Smith ME, et al. (2008) Rhabdoid tumor growth is inhibited by flavopiridol. Clin Cancer Res 14:523-532.
    • (2008) Clin Cancer Res , vol.14 , pp. 523-532
    • Smith, M.E.1
  • 12
    • 33748331308 scopus 로고    scopus 로고
    • The mighty mouse: Genetically engineered mouse models in cancer drug development
    • Sharpless NE, Depinho RA (2006) The mighty mouse: Genetically engineered mouse models in cancer drug development. Nat Rev Drug Discov 5:741-754.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 741-754
    • Sharpless, N.E.1    Depinho, R.A.2
  • 13
    • 0036061877 scopus 로고    scopus 로고
    • Atypical teratoid/rhabdoid tumor of the central nervous system: Report on workshop
    • Packer RJ, et al. (2002) Atypical teratoid/rhabdoid tumor of the central nervous system: Report on workshop. J Pediatr Hematol Oncol 24:337-342.
    • (2002) J Pediatr Hematol Oncol , vol.24 , pp. 337-342
    • Packer, R.J.1
  • 14
    • 20844442622 scopus 로고    scopus 로고
    • 18F]FDG uptake and PCNA, Glut-1, and Hexokinase-II expressions in cancers and inflammatory lesions of the lung
    • 18F]FDG uptake and PCNA, Glut-1, and Hexokinase-II expressions in cancers and inflammatory lesions of the lung. Neoplasia 7:369-379.
    • (2005) Neoplasia , vol.7 , pp. 369-379
    • Mamede, M.1
  • 15
    • 0034059086 scopus 로고    scopus 로고
    • Membranous expression of glucose transporter-1 protein (GLUT-1) in embryonal neoplasms of the central nervous system
    • Loda M, Xu X, Pession A, Vortmeyer A, Giangaspero F (2000) Membranous expression of glucose transporter-1 protein (GLUT-1) in embryonal neoplasms of the central nervous system. Neuropathol Appl Neurobiol 26:91-97.
    • (2000) Neuropathol Appl Neurobiol , vol.26 , pp. 91-97
    • Loda, M.1    Xu, X.2    Pession, A.3    Vortmeyer, A.4    Giangaspero, F.5
  • 16
    • 34147192050 scopus 로고    scopus 로고
    • Germlinemutation of INI1/SMARCB1 in familial schwannomatosis
    • Hulsebos TJ, et al. (2007) Germlinemutation of INI1/SMARCB1 in familial schwannomatosis. Am J Hum Genet 80:805-810.
    • (2007) Am J Hum Genet , vol.80 , pp. 805-810
    • Hulsebos, T.J.1
  • 17
    • 20144386270 scopus 로고    scopus 로고
    • SMARCB1/INI1 tumor suppressor gene is frequently inactivated in epithelioid sarcomas
    • Modena P, et al. (2005) SMARCB1/INI1 tumor suppressor gene is frequently inactivated in epithelioid sarcomas. Cancer Res 65:4012-4019.
    • (2005) Cancer Res , vol.65 , pp. 4012-4019
    • Modena, P.1
  • 18
    • 58549117718 scopus 로고    scopus 로고
    • Familial occurrence of schwannomas and malignant rhabdoid tumour associated with a duplication in SMARCB1
    • Swensen JJ, et al. (2009) Familial occurrence of schwannomas and malignant rhabdoid tumour associated with a duplication in SMARCB1. J Med Genet 46:68-72.
    • (2009) J Med Genet , vol.46 , pp. 68-72
    • Swensen, J.J.1
  • 19
    • 0036369822 scopus 로고    scopus 로고
    • Atypical teratoid/rhabdoid tumors of the central nervous system: Clinical, radiographic and pathologic features
    • Bambakidis NC, Robinson S, Cohen M, Cohen AR (2002) Atypical teratoid/rhabdoid tumors of the central nervous system: Clinical, radiographic and pathologic features. Pediatr Neurosurg 37:64-70.
    • (2002) Pediatr Neurosurg , vol.37 , pp. 64-70
    • Bambakidis, N.C.1    Robinson, S.2    Cohen, M.3    Cohen, A.R.4
  • 20
    • 0032963671 scopus 로고    scopus 로고
    • c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function
    • Cheng SW, et al. (1999) c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function. Nat Genet 22:102-105.
    • (1999) Nat Genet , vol.22 , pp. 102-105
    • Cheng, S.W.1
  • 21
    • 0038066467 scopus 로고    scopus 로고
    • The Septin 9 (MSF) gene is amplified and overexpressed in mouse mammary gland adenocarcinomas and human breast cancer cell lines
    • Montagna C, et al. (2003) The Septin 9 (MSF) gene is amplified and overexpressed in mouse mammary gland adenocarcinomas and human breast cancer cell lines. Cancer Res 63:2179-2187.
    • (2003) Cancer Res , vol.63 , pp. 2179-2187
    • Montagna, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.