Association of the HLA-G gene polymorphism with multiple sclerosis in a Polish population

International Journal of Immunogenetics

Volumn 37, Issue 4, 2010, Pages 307-311

  Wisniewski A ^a   Bilin M ^b   Klimczak, A ^a   Wagner, M ^a   Majorczyk, E ^a   Nowak, I ^a   Pokryszko Dragan, A ^b   Kusnierczyk P ^a,c  

^a INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

^b WROCLAW MEDICAL UNIVERSITY   (Poland)

^c JAN DLUGOSZ UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

HLA G ANTIGEN;

3' UNTRANSLATED REGION; ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CLINICAL ASSESSMENT; CONTROLLED STUDY; DNA EXTRACTION; DNA SEQUENCE; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; POLAND; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

3' UNTRANSLATED REGIONS; ADOLESCENT; ADULT; CASE-CONTROL STUDIES; EXONS; FEMALE; GENES, MHC CLASS I; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HLA-G ANTIGENS; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; POLAND; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 78651092675     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/j.1744-313X.2010.00926.x     Document Type: Article

References (18)

1. Airas, L., Nikula, T., Huang, Y.-H., Lahesmaa, R. & Wiendl, H. (2007) Postpartum-activation of multiple sclerosis is associated with down-regulation of tolerogenic HLA-G. Journal of Neuroimmunology, 187, 205.
2. Carosella, D.E., Favier, B., Rouas-Freiss, N., Moreau, P. & LeMaoult, J. (2008) Beyond the increasing complexity of the immunomodulatory HLA-G. Blood, 111, 4862.
3. Casetta, I. & Granieri, E. (2000) Prognosis of multiple sclerosis: environmental factors. Neurological Sciences, 21, S839.
4. Ebers, G.C., Sadovnick, A.D. & Risch, N.J. (1995) A genetic basis for familial aggregation in multiple sclerosis. The Canadian Collaborative Study Group. Nature, 377, 150.
5. Favier, B., LeMaoult, J. & Carosella, E.D. (2007) Function of HLA-G in the immune system. Tissue Antigens, Journal Compilation, 69(Suppl. 1), 150.
6. Hviid, T.V.F., Hylenius, S., Rorbye, C. & Nielsen, L.G. (2003) HLA-G allelic variants are associated with differences in the HLA-G mRNA isoform profile and HLA-G mRNA levels. Immunogenetics, 55, 63.
7. Hylenius, S., Andersen, A.-M.N., Melbye, M. & Hviid, T.V.F. (2004) Association between HLA-G genotype and risk of preeclampsia: a case-control study using family triads. Molecular Human Reproduction, 10, 237.
8. Kenealy, S.J., Pericak-Vance, M.A. & Haines, J.L. (2003) The genetic epidemiology of multiple sclerosis. Journal of Neuroimmunology, 143, 7.
9. Kroner, A., Grimm, A., Johannssen, K., Maurer, M. & Wiendl, H. (2007) The genetic influence of the nonclassical MHC HLA-G on multiple sclerosis. Human Immunology, 68, 422.
10. Kurtzke, J.F. (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status score (EDSS). Neurology, 33, 1444.
11. Moreau, P., Mouillot, G., Rousseau, P., Marcou, C., Dausset, J. & Carosella, E.D. (2003) HLA-G gene repression is reversed by demethylation. Proceedings of the National Academy of Sciences of the United States of America, 100, 1191.
12. Mumford, C.J., Wood, N.W., Kellar-Wood, H., Thorpe, J.W., Miller, D.H. & Compston, D.A. (1994) The British Isles survey of multiple sclerosis in twins. Neurology, 44, 11.
13. Ober, C., Aldrich, L., Chervoneva, I., Billstrand, C., Rahimov, F., Gray, H.L. & Hyslop, T. (2003) Variation in the HLA-G promoter region influences miscarriage rates. The American Journal of Human Genetics, 72, 1425.
14. Poser, C.M., Paty, D.W., Scheinberg, L., McDonald, W.I., Davis, F.A., Ebers, G.C., Johnson, K.P., Sibley, W.A., Silberberg, D.H. & Tourtellotte, W.W. (1983) New diagnostic criteria for multiple sclerosis; guidelines for research protocols. Annals of Neurology, 13, 227.
15. Sadovnik, A.D., Armstrong, H., Rice, G.P., Bulman, D., Hashimoto, L., Party, D.W. et al. (1993) A population-based study of multiple sclerosis in twins: update. Annals of Neurology, 33, 281.
16. The International Multiple Sclerosis Genetics Consortium, (2007) A second major histocompatibility complex susceptibility locus for multiple sclerosis. Annals of Neurology, 61, 228.
17. Tripathi, P., Abbas, A., Naik, S. & Agrawal, S. (2004) Role of 14-bp deletion in the HLA-G gene in the maintenance of pregnancy. Tissue Antigens, 64, 706.
18. Wiendl, H., Feger, U., Mittelbronn, M., Jack, C., Schreiner, B., Stadelmann, C. et al. (2005) Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity. Brain, 128, 2689.