Pure flat epithelial atypia (DIN 1a) on core needle biopsy: Study of 60 biopsies with follow-up surgical excision

Breast Cancer Research and Treatment

Volumn 125, Issue 1, 2011, Pages 121-126

  Lavoué, Vincent ^a,b   Roger, Claire Marie ^a,b   Poilblanc, Mathieu ^c,d   Proust, Nicolas ^d   Monghal Verge, Camille ^e   Sagan, Christine ^f   Tas, Patrick ^a   Mesbah, Habiba ^a   Porée, Philippe ^a   Gay, Catherine ^g   Body, Gilles ^c   Levêque, Jean ^a,b  

^a Eugène Marquis Comprehensive Cancer Center   (France)

^b RENNES UNIVERSITY HOSPITAL   (France)

^c ANGERS UNIVERSITY HOSPITAL   (France)

^d Cancer Center ICO René Gauducheau   (France)

^e CHU BRETONNEAU   (France)

^f NANTES UNIVERSITY HOSPITAL   (France)

^g NONE   (France)

Author keywords

Breast cancer; Core needle biopsy; Flat epithelial atypia; Surgical excision

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR;

ADULT; AGED; ARTICLE; BREAST BIOPSY; BREAST CARCINOMA; BREAST HYPERPLASIA; CONTROLLED STUDY; EXCISION; FEMALE; FLAT EPITHELIAL ATYPIA; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTRADUCTAL CARCINOMA; MAJOR CLINICAL STUDY; NEEDLE BIOPSY; PRECANCER; PRIORITY JOURNAL; STEREOTACTIC BIOPSY; TUMOR VOLUME;

ADULT; AGED; BIOPSY, NEEDLE; BREAST NEOPLASMS; CARCINOMA; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CHI-SQUARE DISTRIBUTION; FEMALE; FRANCE; HUMANS; HYPERPLASIA; MAMMARY GLANDS, HUMAN; MAMMOGRAPHY; MIDDLE AGED; NEOPLASM INVASIVENESS; PRECANCEROUS CONDITIONS; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 78651089695     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1208-1     Document Type: Article

References (27)

1. I De Mascarel G MacGrogan 2007 Prise en charge des atypies épithéliales du sein Ann Pathol 27 3 182 194 10.1016/S0242- 6498(07)91849-0 17978689 (Pubitemid 47619786)
2. WD Dupont DL Page 1985 Risk factors for breast cancer in women with proliferative breast disease N Engl J Med 312 3 146 151 1:STN:280: DyaL2M%2Fos1Wguw%3D%3D 10.1056/NEJM198501173120303 3965932
3. Tavassoli FA, Millis RR, Boecker W, Lakhani SR (2003) Lobular neoplasia. In: Tavassoli FA, Devilee P (eds) Tumors of the breast and female genital organs. World Health Organization Classification of tumours. IARC press, Lyon, pp 60-64
4. MM Guerra-Wallace WN Christensen RL White Jr 2004 A retrospective study of columnar alteration with prominent apical snouts and secretions and the association with cancer Am J Surg 188 4 395 398 10.1016/j.amjsurg.2004.06.037 15474433 (Pubitemid 39330543)
5. NS Goldstein BA O'Malley 1997 Cancerization of small ectatic ducts of the breast by ductal carcinoma in situ cells with apocrine snouts: a lesion associated with tubular carcinoma Am J Clin Pathol 107 5 561 566 1:STN:280:DyaK2s3nsVWhsw%3D%3D 9128269
6. JL Fraser S Raza K Chorny, et al. 1998 Columnar alteration with prominent apical snouts and secretions: a spectrum of changes frequently present in breast biopsies performed for microcalcifications Am J Surg Pathol 22 12 1521 1527 1:STN:280:DyaK1M%2FmsFCgsg%3D%3D 10.1097/00000478-199812000-00009 9850178 (Pubitemid 28550647)
7. T Oyama K Iijima H Takei, et al. 2000 Atypical cystic lobule of the breast: an early stage of low-grade ductal carcinoma in situ Breast Cancer 7 4 326 331 1:STN:280:DC%2BD3M3lvFyjsA%3D%3D 10.1007/BF02966399 11114859
8. FA Tavassoli 1998 Ductal carcinoma in situ: introduction of the concept of ductal intraepithelial neoplasia Mod Pathol 11 2 140 154 1:STN:280: DyaK1c7mtlaisQ%3D%3D 9504685
9. TM Abdel-Fatah DG Powe Z Hodi, et al. 2008 Morphologic and molecular evolutionary pathways of low nuclear grade invasive breast cancers and their putative precursor lesions: further evidence to support the concept of low nuclear grade breast neoplasia family Am J Surg Pathol 32 4 513 523 10.1097/PAS.0b013e318161d1a5 18223478 (Pubitemid 351458293)
10. F Moinfar YG Man GL Bratthauer, et al. 2000 Genetic abnormalities in mammary ductal intraepithelial neoplasia-flat type ("clinging ductal carcinoma in situ"): a simulator of normal mammary epithelium Cancer 88 9 2072 2081 1:CAS:528:DC%2BD3cXjtF2murc%3D 10.1002/(SICI)1097-0142(20000501)88: 9<2072::AID-CNCR13>3.0.CO;2-H 10813719 (Pubitemid 30233209)
11. JS Reis-Filho PT Simpson C Jones, et al. 2005 Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity J Pathol 207 1 1 13 1:CAS:528:DC%2BD2MXhtVemtrzK 10.1002/path.1806 15957152 (Pubitemid 41200708)
12. SJ Schnitt 2003 The diagnosis and management of pre-invasive breast disease: flat epithelial atypia-classification, pathologic features and clinical significance Breast Cancer Res 5 5 263 268 10.1186/bcr625 12927037 (Pubitemid 37080857)
13. PR Eby JE Ochsner WB DeMartini, et al. 2008 Is surgical excision necessary for focal atypical ductal hyperplasia found at stereotactic vacuum-assisted breast biopsy? Ann Surg Oncol 15 11 3232 3238 10.1245/s10434-008-0100-2 18696163
14. V Lavoue O Graesslin JM Classe, et al. 2007 Management of lobular neoplasia diagnosed by core needle biopsy: study of 52 biopsies with follow-up surgical excision Breast 16 5 533 539 10.1016/j.breast.2007.04.005 17629481 (Pubitemid 47495781)
15. Q Piubello A Parisi A Eccher, et al. 2009 Flat epithelial atypia on core needle biopsy: which is the right management? Am J Surg Pathol 33 1078 1084 10.1097/PAS.0b013e31819d0a4d 19390424
16. LP Kunju CG Kleer 2007 Significance of flat epithelial atypia on mammotome core needle biopsy: should it be excised? Hum Pathol 38 1 35 41 10.1016/j.humpath.2006.08.008 17095049 (Pubitemid 44880218)
17. M Bonnett T Wallis M Rossmann, et al. 2003 Histopathologic analysis of atypical lesions in image-guided core breast biopsies Mod Pathol 16 2 154 160 10.1097/01.MP.0000052375.72841.E2 12591968 (Pubitemid 36245747)
18. S Nasser M Fan 2003 Does atypical columnar cell hyperplasia on breast core biopsy warrant follow up excision? (Abstract) Mod Pathol 15 36A
19. E Brogi L Tan 2002 Findings at excisional biopsy (EBX) performed after identification of columnar cell change (CCC) of ductal epithelium in breast core biopsy (CBX) (Abstract) Mod Pathol 15 15 29A 30A
20. A Noske S Pahl E Fallenberg, et al. 2009 Flat epithelial atypia is a common subtype of B3 breast lesions and associated with noninvasive cancer but not with invasive cancer in final excision histology Hum Pathol 41 522 527 10.1016/j.humpath.2009.09.005 20004938
21. A Noske S Pahl E Fallenberg, et al. 2010 Flat epithelial atypia is a common subtype of B3 breast lesions and is associated with noninvasive cancer but not with invasive cancer in final excision histology Hum Pathol 41 4 522 527 1:CAS:528:DC%2BC3cXjtFyiurw%3D 10.1016/j.humpath.2009.09.005 20004938
22. American College of Radiology (1995) Breast imaging reporting and data system (BI-RADS) 2nd ed. Reston, VA: American College of Radiology
23. M Martel P Barron-Rodriguez I Tolgay Ocal, et al. 2007 Flat DIN 1 (flat epithelial atypia) on core needle biopsy: 63 cases identified retrospectively among 1, 751 core biopsies performed over an 8-year period (1992-1999) Virchows Arch 451 5 883 891 10.1007/s00428-007-0499-z 17786469 (Pubitemid 350060744)
24. GL Bratthauer FA Tavassoli 2004 Assessment of lesions coexisting with various grades of ductal intraepithelial neoplasia of the breast Virchows Arch 444 4 340 344 10.1007/s00428-004-0976-6 14986131 (Pubitemid 38553638)
25. FI Boulos WD Dupont JF Simpson, et al. 2008 Histologic associations and long-term cancer risk in columnar cell lesions of the breast: a retrospective cohort and a nested case-control study Cancer 113 9 2415 2421 10.1002/cncr.23873 18816618
26. PH Tan BC Ho S Selvarajan, et al. 2005 Pathological diagnosis of columnar cell lesions of the breast: are there issues of reproducibility? J Clin Pathol 58 7 705 709 1:STN:280:DC%2BD2Mzis1ajsg%3D%3D 10.1136/jcp.2004.025239 15976336 (Pubitemid 40956823)
27. FP O'Malley SK Mohsin S Badve, et al. 2006 Interobserver reproducibility in the diagnosis of flat epithelial atypia of the breast Mod Pathol 19 2 172 179 10.1038/modpathol.3800514 16424892 (Pubitemid 43117601)