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Volumn 56, Issue 3, 2011, Pages 420-424

Improved efficacy and tolerability of oral deferasirox by twice-daily dosing for patients with transfusion-dependent β-thalassemia

Author keywords

Deferasirox; Iron overload; Thalassemia; Twice daily dosing

Indexed keywords

DEFERASIROX; FERRITIN;

EID: 78651061167     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.22826     Document Type: Article
Times cited : (35)

References (11)
  • 1
    • 33646391919 scopus 로고    scopus 로고
    • Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: New data, new questions
    • Neufeld EJ. Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: New data, new questions. Blood 2006; 107: 3436-3441.
    • (2006) Blood , vol.107 , pp. 3436-3441
    • Neufeld, E.J.1
  • 2
    • 70450219836 scopus 로고    scopus 로고
    • Deferasirox (Exjade) for the treatment of iron overload
    • Cappellini MD, Taher A. Deferasirox (Exjade) for the treatment of iron overload. Acta Haematol 2009; 122: 165-173.
    • (2009) Acta Haematol , vol.122 , pp. 165-173
    • Cappellini, M.D.1    Taher, A.2
  • 3
    • 33749991316 scopus 로고    scopus 로고
    • Phase II clinical evaluation of deferasirox, a once-daily oral chelating agent, in pediatric patients with beta-thalassemia major
    • Galanello R, Piga A, Forni GL, et al. Phase II clinical evaluation of deferasirox, a once-daily oral chelating agent, in pediatric patients with beta-thalassemia major. Haematologica 2006; 91: 1343-1351.
    • (2006) Haematologica , vol.91 , pp. 1343-1351
    • Galanello, R.1    Piga, A.2    Forni, G.L.3
  • 4
    • 33646414765 scopus 로고    scopus 로고
    • A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia
    • Cappellini MD, Cohen A, Piga A, et al. A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia. Blood 2006; 107: 3455-3462.
    • (2006) Blood , vol.107 , pp. 3455-3462
    • Cappellini, M.D.1    Cohen, A.2    Piga, A.3
  • 5
    • 70449403619 scopus 로고    scopus 로고
    • Efficacy and safety of deferasirox doses of >30 mg/kg per day in patients with transfusion-dependent anaemia and iron overload
    • Taher A, Cappellini MD, Vichinsky E, et al. Efficacy and safety of deferasirox doses of >30 mg/kg per day in patients with transfusion-dependent anaemia and iron overload. Br J Haematol 2009; 147: 752-759.
    • (2009) Br J Haematol , vol.147 , pp. 752-759
    • Taher, A.1    Cappellini, M.D.2    Vichinsky, E.3
  • 6
    • 77950425913 scopus 로고    scopus 로고
    • Deferasirox pharmacokinetics in patients with adequate versus inadequate response
    • Chirnomas D, Smith AL, Braunstein J, et al. Deferasirox pharmacokinetics in patients with adequate versus inadequate response. Blood 2009; 114: 4009-4013.
    • (2009) Blood , vol.114 , pp. 4009-4013
    • Chirnomas, D.1    Smith, A.L.2    Braunstein, J.3
  • 7
    • 33745774771 scopus 로고    scopus 로고
    • Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload
    • Piga A, Galanello R, Forni GL, et al. Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload. Haematologica 2006; 91: 873-880.
    • (2006) Haematologica , vol.91 , pp. 873-880
    • Piga, A.1    Galanello, R.2    Forni, G.L.3
  • 8
    • 77950682176 scopus 로고    scopus 로고
    • Tailoring iron chelation by iron intake and serum ferritin: The prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias
    • Cappellini MD, Porter J, El-Beshlawy A, et al. Tailoring iron chelation by iron intake and serum ferritin: The prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias. Haematologica 2010; 95: 557-566.
    • (2010) Haematologica , vol.95 , pp. 557-566
    • Cappellini, M.D.1    Porter, J.2    El-Beshlawy, A.3
  • 9
    • 0037906104 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron overload due to beta-thalassemia
    • Galanello R, Piga A, Alberti D, et al. Safety, tolerability, and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron overload due to beta-thalassemia. J Clin Pharmacol 2003; 43: 565-572.
    • (2003) J Clin Pharmacol , vol.43 , pp. 565-572
    • Galanello, R.1    Piga, A.2    Alberti, D.3
  • 10
    • 10744230223 scopus 로고    scopus 로고
    • Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: A randomised, double-blind, placebo-controlled, dose-escalation trial
    • Nisbet-Brown E, Olivieri NF, Giardina PJ, et al. Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: A randomised, double-blind, placebo-controlled, dose-escalation trial. Lancet 2003; 361: 1597-1602.
    • (2003) Lancet , vol.361 , pp. 1597-1602
    • Nisbet-Brown, E.1    Olivieri, N.F.2    Giardina, P.J.3
  • 11
    • 34250360747 scopus 로고    scopus 로고
    • Comparison of twice-daily vs once-daily deferasirox dosing in a gerbil model of iron cardiomyopathy
    • Otto-Duessel M, Aguilar M, Nick H, et al. Comparison of twice-daily vs once-daily deferasirox dosing in a gerbil model of iron cardiomyopathy. Exp Hematol 2007; 35: 1069-1073.
    • (2007) Exp Hematol , vol.35 , pp. 1069-1073
    • Otto-Duessel, M.1    Aguilar, M.2    Nick, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.