Nonalcoholic fatty liver disease in a severely obese adolescent. An arguable liver biopsy;Stéatohépatite non alcoolique chez une adolescente obèse: une biopsie hépatique discutable

Archives de Pediatrie

Volumn 18, Issue 1, 2011, Pages 62-65

  Bertrand, J B ^a,b   Lefevre H ^a   Prevot S ^c,d   Perlemuter, G ^c,d,e  

^a université Paris Cité   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c HÔPITAL ANTOINE BÉCLÈRE   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e Universite Paris Sud   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CASE REPORT; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ACTIVITY; DISEASE COURSE; DISEASE SEVERITY; ECHOGRAPHY; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; LIVER BIOPSY; LIVER FIBROSIS; NONALCOHOLIC FATTY LIVER; OBESITY; PATIENT MONITORING; WEIGHT REDUCTION;

ADOLESCENT; BIOPSY; FATTY LIVER; FEMALE; HUMANS; LIVER; OBESITY; SEVERITY OF ILLNESS INDEX;

EID: 78650994372     PISSN: 0929693X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcped.2010.10.010     Document Type: Article

References (20)

1. (consulté en mai 2010). http://www.idf.org/webdata/docs/Metabolic_syndrome_definition.pdf.
2. Perlemuter G., Bigorgne A., Cassard-Doulcier A.M., et al. Non-alcoholic fatty liver disease: from pathogenesis to patient care. Nat Clin Pract Endocrinol Metab 2007, 3:458-469.
3. Patton HM, Yates K, Unalp-Arida A, et al. Association between metabolic syndrome and liver histology among children with non-alcoholic fatty liver disease. Am J Gastroenterol 2010;105:2093-102.
4. Alisi A., Manco M., Vania A., et al. Pediatric non-alcoholic fatty liver disease in 2009. J Pediatr 2009, 155:469-474.
5. Viner R.M., Segal T.Y., Lichtarowicz-Krynska E., et al. Prevalence of the insulin resistance syndrome in obesity. Arch Dis Child 2005, 90:10-14.
6. Mimoun E., Aggoun Y., Pousset M., et al. Association of arterial stiffness and endothelial dysfunction with metabolic syndrome in obese children. J Pediatr 2008, 153:65-70.
7. Eppens M.C., Craig M.E., Cusumano J., et al. Prevalence of diabetes complications in adolescents with type 2 compared with type 1 diabetes. Diabetes care 2006, 29:1300-1306.
8. Schwimmer J.B., Deutsch R., Kahen T., et al. Prevalence of fatty liver in children and adolescents. Pediatrics 2006, 118:1388-1393.
9. Carter-Kent C., Yerian L.M., Brunt E.M., et al. Non-alcoholic steatohepatitis in children: a multicenter clinicopathological study. Hepatology 2009, 50:1113-1120.
10. Day C.P., James O.F. Steatohepatitis: a tale of two "hits" ?. Gastroenterology 1998, 114:8425.
11. Marion A.W., Baker A.J., Dhawan A. Fatty liver disease in children. Arch Dis Child 2004, 89:648-652.
12. Nobili V., Manco M., Ciampalini P., et al. Leptin, free leptin index, insulin resistance and liver fibrosis in children with non-alcoholic fatty liver disease. Eur J Endocrinol 2006, 155:735-743.
13. Rockey D.C., Caldwell S.H., Goodman Z.D., et al. Liver biopsy. American association for the study of liver diseases. Hepatology 2009, 49:1017-1044.
14. Roberts E.A. Pediatric non-alcoholic fatty liver disease (NAFLD): a "growing" problem?. J Hepatol 2007, 46:1133-1142.
15. Argo C.K., Northup P.G., Al-Osaimi A.M.S., et al. Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis. J Hepatol 2009, 51:371-379.
16. Oude Luttikhuis H, Baur L, Jansen H, et al. Interventions for treating obesity in children. Cochrane Database Syst Rev 2009, CD001872.
17. Sanyal A.J., Chalasani N., Kowdley K.V., et al. Pioglitazone, vitamin E, or placebo for non-alcoholic steatohepatitis. N Engl J Med 2010, 362:1675-1685.
18. Mofrad P., Contos M.J., Haque M., et al. Clinical and histologic spectrum of non-alcoholic fatty liver disease associated with normal ALT values. Hepatology 2003, 37:1286-1292.
19. Nobili V., Parkes J., Bottazzo G., et al. Performance of ELF serum markers in predicting fibrosis stage in pediatric non-alcoholic fatty liver disease. Gastroenterology 2009, 136:160-167.
20. Nobili V., Vizzutti F., Arena U., et al. Accuracy and reproducibility of transient elastography for the diagnosis of fibrosis in pediatric non-alcoholic steatohepatitis. Hepatology 2008, 48:442-448.