Usefulness of the serum lactate concentration for predicting mortality in acute beta-blocker poisoning

Clinical Toxicology

Volumn 48, Issue 10, 2010, Pages 974-978

  Mégarbane, Bruno ^a,b   Deye, Nicolas ^a,b   Malissin, Isabelle ^a   Baud, Frédéric J ^a,b  

^a HÔPITAL LARIBOISIÈRE   (France)

^b INSERM   (France)

Author keywords

Beta blocker; Cardiovascular failure; Lactate; Mortality; Poisoning

Indexed keywords

ACEBUTOLOL; ALCOHOL; ALPRAZOLAM; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLONAZEPAM; CLORAZEPATE POTASSIUM; DIACETOLOL; IBUPROFEN; LACTIC ACID; NITRAZEPAM; PARACETAMOL; PROPRANOLOL; RAMIPRIL; RISPERIDONE; ZOPICLONE;

ADULT; ARTICLE; CARDIOVASCULAR SYMPTOM; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG FATALITY; DRUG INTOXICATION; FEMALE; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE UNIT; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MORTALITY; PROGNOSIS; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SURVIVAL;

ACUTE DISEASE; ADRENERGIC BETA-ANTAGONISTS; ADULT; FEMALE; HUMANS; LACTIC ACID; MALE; MIDDLE AGED; POISONING; SENSITIVITY AND SPECIFICITY;

EID: 78650963871     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2010.534483     Document Type: Article

References (10)

1. Bronstein AC, Spyker DA, Cantilena LR Jr, Green JL, Rumack BH,Giffin SL. 2008. Annual report of the American Association of PoisonControl Centers' National Poison Data System (NPDS): 26th annualreport. Clin Toxicol (Phila) 2009; 47:911-1084.
2. Love JN, Litovitz TL, Howell JM, Clancy C. Characterization of fatalbeta blocker ingestion: a review of the American Association ofPoison Control Centers data from 1985 to 1995. J Toxicol ClinToxicol 1997; 35:353-359.
3. Love JN, Howell JM, Litovitz TL, Klein-Schwartz W. Acute betablocker overdose: factors associated with the development ofcardiovascular morbidity. J Toxicol Clin Toxicol 2000; 38:275-281.
4. Manini AF, Kumar A, Olsen D, Vlahov D, Hoffman RS. Utility ofserum lactate to predict drug-overdose fatality. Clin Toxicol (Phila),2010; 48:730-736.
5. Barth E, Albuszies G, Baumgart K, Matejovic M, Wachter U, Vogt J,Radermacher P, Calzia E. Glucose metabolism and catecholamines.Crit Care Med 2007; 35:S508-S518.
6. Júnior PB, Neiva CM, Denadai BS. Effect of an acute beta-adrenergicblockade on the blood glucose response during lactate minimum test.J Sci Med Sport 2001; 4:257-265.
7. Hamann JJ, Kelley KM, Gladden LB. Effect of epinephrine on netlactate uptake by contracting skeletal muscle. J Appl Physiol 2001;91:2635-2641.
8. Luchette FA, Robinson BR, Friend LA, McCarter F, Frame SB, JamesJH. Adrenergic antagonists reduce lactic acidosis in response tohemorrhagic shock. J Trauma 1999; 46:873-880.
9. Mégarbane B, Donetti L, Blanc T, Chéron G, Jacobs F; Grouped'experts de la SRLF. Treatment of acute poisoning by illicit drugs.Recommendations of the French Language Resuscitation Society(SRLF). Rev Prat 2008; 58:871-881.
10. Wax PM, Erdman AR, Chyka PA, Keyes DC, Caravati EM, Booze L,et al. Beta-blocker ingestion: an evidence-based consensus guidelinefor out-of-hospital management. Clin Toxicol (Phila) 2005; 43:131-146.