Fulminant hepatitis and death associated with disseminated varicella in an immunocompromised adult from the Czech Republic caused by a wild-type clade 4 varicella-zoster virus strain

Journal of Clinical Virology

Volumn 50, Issue 1, 2011, Pages 72-75

  Plisek, Stanislav ^a   Pliskova, Lenka ^a   Bostik, Vanda ^b   Prasil, Petr ^a   Laco, Jan ^a   Chlibek, Roman ^b   Vyroubal, Pavel ^a   Kosina, Pavel ^a   Bostik, Pavel ^a,b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b UNIVERSITY OF DEFENCE   (Czech Republic)

Author keywords

Hepatitis; Immunosuppression; Molecular epidemiology; Single nucleotide polymorphisms (SNP); Varicella zoster virus (VZV)

Indexed keywords

ACICLOVIR; ALANINE AMINOTRANSFERASE; ANTITHROMBIN III; ASPARTATE AMINOTRANSFERASE; BLOOD CLOTTING FACTOR; CRYOPROTEIN; FIBRINOGEN; METHYLPREDNISOLONE; METHYLPREDNISOLONE SODIUM SUCCINATE; PROTROCOMPLEX TOTAL; UNCLASSIFIED DRUG; VIRUS DNA;

ABDOMINAL PAIN; ACUTE LIVER FAILURE; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ARTIFICIAL VENTILATION; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOPSY; BLEEDING; BLOOD CLOTTING DISORDER; BRADYCARDIA; BRAIN EDEMA; CASE REPORT; CAUSE OF DEATH; CHICKENPOX; CLADISTICS; CLINICAL EXAMINATION; COMPARTMENT SYNDROME; CZECH REPUBLIC; DEMYELINATION; DEPRESSION; DETERIORATION; DISEASE SEVERITY; DNA DETERMINATION; DYSPNEA; EDEMA; ESOPHAGITIS; ESOPHAGUS; FASCIOTOMY; FEMALE; FIBRINOGEN BLOOD LEVEL; GASTROINTESTINAL SYMPTOM; GASTROSCOPY; GENOTYPE; HEAT; HEPATITIS; HEPATORENAL SYNDROME; HERPES VIRUS INFECTION; HOSPITAL ADMISSION; HUMAN; HUMAN TISSUE; HYPOTENSION; IMMUNOCOMPROMISED PATIENT; INTENSIVE CARE UNIT; INTERNATIONAL NORMALIZED RATIO; LEG CRAMP; LEG DISEASE; LIVER; LUNG HEMORRHAGE; LUNG VOLUME; MORTALITY; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; OPEN READING FRAME; OXYGEN SATURATION; PALLIATIVE THERAPY; PARESTHESIA; PERCEPTION DISORDER; PLASMA TRANSFUSION; POLYMERASE CHAIN REACTION; PRIMARY INFECTION; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; PROTHROMBIN TIME; RASH; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN; TREATMENT DURATION; URINALYSIS; VARICELLA ZOSTER VIRUS; VESICULAR RASH; VOMITING; WILD TYPE;

ADULT; CHICKENPOX; CZECH REPUBLIC; FATAL OUTCOME; FEMALE; GENES, VIRAL; GENOTYPE; HEPATITIS; HERPESVIRUS 3, HUMAN; HUMANS; IMMUNOCOMPROMISED HOST; IMMUNOSUPPRESSIVE AGENTS;

EID: 78650930611     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2010.09.014     Document Type: Article

References (31)

1. Arvin A.M. Varicella-zoster virus: molecular virology and virus-host interactions. Curr Opin Microbiol 2001, 4:442-449.
2. Arvin A.M. Chickenpox (varicella). Contrib Microbiol 1999, 3:96-110.
3. Arvin A.M. Varicella-zoster virus. Clin Microbiol Rev 1996, 9:361-381.
4. Arvin A.M. Varicella-zoster virus: overview and clinical manifestations. Semin Dermatol 1996, 15:4-7.
5. Borum M.L., Zimmerman H.J. Hepatitis associated with varicella infection in an immunocompetent adult. J Clin Gastroenterol 1996, 23:165.
6. Bovill B., Bannister B. Review of 26 years' hospital admissions for chickenpox in North London. J Infect 1998, 36(Suppl 1):17-23.
7. Smith C.K., Arvin A.M. Varicella in the fetus and newborn. Semin Fetal Neonatal Med 2009, 14:209-217.
8. McKendrick M.W., Lau J., Alston S., Bremner J. VZV infection in pregnancy: a retrospective review over 5 years in Sheffield and discussion on the potential utilisation of varicella vaccine in prevention. J Infect 2007, 55:64-67.
9. Hackanson B., Zeiser R., Bley T.A., Pantazis G., Huzly D., Bertz H., et al. Fatal varicella zoster virus encephalitis in two patients following allogeneic hematopoietic stem cell transplantation. Clin Transplant 2005, 19:566-570.
10. Hyvernat H., Roger P.M., Pereira C., Saint-Paul M.C., Vandenbos F., Bernardin G. Fatal varicella hepatitis in an asthmatic adult after short-term corticosteroid treatment. Eur J Intern Med 2005, 16:361-362.
11. Springfeld C., Sauerbrei A., Filusch A., Konstandin M., Hartschuh W., Sauer P., et al. Fatal varicella in an immunocompromised adult associated with a European genotype E2 variant of varicella zoster virus. J Clin Virol 2009, 44:70-73.
12. Chen P.Y., Chu H.Y., Shian W.J., Shu S.G., Chi C.S. Varicella-zoster virus infection in children with malignancy. Zhonghua Yi Xue Za Zhi (Taipei) 1994, 54:417-423.
13. Ho C.M., Khuzaiah R., Yasmin A.M. Varicella in children with haematological malignancy - outcome of treatment and prevention. Med J Malaysia 1994, 49:29-35.
14. Loparev V.N., McCaustland K., Holloway B.P., Krause P.R., Takayama M., Schmid D.S. Rapid genotyping of varicella-zoster virus vaccine and wild-type strains with fluorophore-labeled hybridization probes. J Clin Microbiol 2000, 38:4315-4319.
15. Loparev V.N., Rubtcova E.N., Bostik V., Govil D., Birch C.J., Druce J.D., et al. Identification of five major and two minor genotypes of varicella-zoster virus strains: a practical two-amplicon approach used to genotype clinical isolates in Australia and New Zealand. J Virol 2007, 81:12758-12765.
16. Loparev V.N., Rubtcova E.N., Bostik V., Tzaneva V., Sauerbrei A., Robo A., et al. Distribution of varicella-zoster virus (VZV) wild-type genotypes in northern and southern Europe: evidence for high conservation of circulating genotypes. Virology 2009, 383:216-225.
17. Loparev V.N., Gonzalez A., Deleon-Carnes M., Tipples G., Fickenscher H., Torfason E.G., et al. Global identification of three major genotypes of varicella-zoster virus: longitudinal clustering and strategies for genotyping. J Virol 2004, 78:8349-8358.
18. Rowland P., Wald E.R., Mirro J.R., Yunis E., Albo V.C., Wollman M.R., et al. Progressive varicella presenting with pain and minimal skin involvement in children with acute lymphoblastic leukemia. J Clin Oncol 1995, 13:1697-1703.
19. Mantadakis E., Anagnostatou N., Danilatou V., Markaki E.A., Spanaki A.M., Briassoulis G., et al. Fulminant hepatitis due to varicella zoster virus in a girl with acute lymphoblastic leukemia in remission: report of a case and review. J Pediatr Hematol Oncol 2005, 27:551-553.
20. Mizoguchi F., Nakamura S., Iwai H., Kubota T., Miyasaka N. Varicella-zoster virus hepatitis in polymyositis. Mod Rheumatol 2008, 18:301-305.
21. Anderson D.R., Schwartz J., Hunter N.J., Cottrill C., Bisaccia E., Klainer A.S. Varicella hepatitis: a fatal case in a previously healthy, immunocompetent adult. Report of a case, autopsy, and review of the literature. Arch Intern Med 1994, 154:2101-2106.
22. Natoli S., Ciotti M., Paba P., Testore G.P., Palmieri G., Orlandi A., et al. A novel mutation of varicella-zoster virus associated to fatal hepatitis. J Clin Virol 2006, 37:72-74.
23. Dowell S.F., Bresee J.S. Severe varicella associated with steroid use. Pediatrics 1993, 92:223-228.
24. Abzug M.J., Cotton M.F. Severe chickenpox after intranasal use of corticosteroids. J Pediatr 1993, 123:577-579.
25. Quinlivan M., Hawrami K., Barrett-Muir W., Aaby P., Arvin A., Chow V.T., et al. The molecular epidemiology of varicella-zoster virus: evidence for geographic segregation. J Infect Dis 2002, 186:888-894.
26. Muir W.B., Nichols R., Breuer J. Phylogenetic analysis of varicella-zoster virus: evidence of intercontinental spread of genotypes and recombination. J Virol 2002, 76:1971-1979.
27. Larussa P.S., Gershon A.A. Biologic and geographic differences between vaccine and clinical varicella-zoster virus isolates. Arch Virol Suppl 2001, 41-48.
28. Loparev V., Martro E., Rubtcova E., Rodrigo C., Piette J.C., Caumes E., et al. Toward universal varicella-zoster virus (VZV) genotyping: diversity of VZV strains from France and Spain. J Clin Microbiol 2007, 45:559-563.
29. Breuer J., Grose C., Norberg P., Tipples G., Schmid D.S. A proposal for a common nomenclature for viral clades that form the species varicella-zoster virus: summary of VZV Nomenclature Meeting 2008, Barts and the London School of Medicine and Dentistry. J Gen Virol 2008, 91:821-828.
30. Sergeev N., Rubtcova E., Chizikov V., Schmid D.S., Loparev V.N. New mosaic subgenotype of varicella-zoster virus in the USA: VZV detection and genotyping by oligonucleotide-microarray. J Virol Methods 2006, 136:8-16.
31. Read S.J., Kurtz J.B. Laboratory diagnosis of common viral infections of the central nervous system by using a single multiplex PCR screening assay. J Clin Microbiol 1999, 37:1352-1355.