Fulminant hepatitis due to varicella zoster virus in a girl with acute lymphoblastic leukemia in remission: Report of a case and review

Journal of Pediatric Hematology/Oncology

Volumn 27, Issue 10, 2005, Pages 551-553

  Mantadakis, Elpis ^a   Anagnostatou, Nicole ^a   Danilatou, Vassiliki ^a   Markaki, Erasmia Athina ^a   Spanaki, Anna Maria ^a   Briassoulis, George ^a   Kalmanti, Maria ^a  

^a UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

Author keywords

Acute lymphoblastic leukemia; Acyclovir; Liver failure; Polymerase chain reaction; Varicella

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ACETYLCYSTEINE; ACICLOVIR; ALANINE AMINOTRANSFERASE; ASPARAGINASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; D DIMER; DEXAMETHASONE; GAMMA GLUTAMYLTRANSFERASE; HERPES ZOSTER IMMUNOGLOBULIN; LACTATE DEHYDROGENASE; LACTULOSE; LIPID; NEOMYCIN; PROTHROMBIN;

ABDOMINAL PAIN; ACUTE LYMPHOBLASTIC LEUKEMIA; ANOREXIA; ARTIFICIAL VENTILATION; BLOOD CELL COUNT; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DEATH; DOPPLER ECHOGRAPHY; DRUG MEGADOSE; FEMALE; FEVER; GLASGOW COMA SCALE; HEPATOMEGALY; HUMAN; IMMUNE DEFICIENCY; INTERNATIONAL NORMALIZED RATIO; IRRITABILITY; LEUKEMIA REMISSION; LIVER FAILURE; LIVER FUNCTION TEST; PARTIAL THROMBOPLASTIN TIME; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; PRURITUS; REVIEW; THORAX RADIOGRAPHY; VARICELLA ZOSTER VIRUS; VIRUS HEPATITIS;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHICKENPOX; CHILD, PRESCHOOL; FATAL OUTCOME; FEMALE; HEPATITIS, VIRAL, HUMAN; HERPESVIRUS 3, HUMAN; HUMANS; IMMUNOCOMPROMISED HOST; LEUKEMIA, LYMPHOCYTIC, ACUTE; LIVER FAILURE, ACUTE; REMISSION INDUCTION;

EID: 27544459391     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/01.mph.0000183272.30570.09     Document Type: Review

References (21)

1. Rowland P, Wald ER, Mirro JR Jr, et al. Progressive varicella presenting with pain and minimal skin involvement in children with acute lymphoblastic leukemia. J Clin Oncol. 1995;13:1697-1703.
2. David DS, Tegtmeier BR, O'Donnell MR, et al. Visceral varicella-zoster after bone marrow transplantation: report of a case series and review of the literature. Am J Gastroenterol. 1998;93:810-813.
3. Dowell SF, Bresce JS. Severe varicella associated with steroid use. Pediatrics. 1993;92:223-228.
4. Tojimbara T, So SK, Cox KL, et al. Fulminant hepatic failure following varicella-zoster infection in a child. A case report of successful treatment with liver transplantation and perioperative acyclovir. Transplantation. 1995;60:1052-1053.
5. Feldman S, Hughes WT, Daniel CB. Varicella in children with cancer: seventy-seven cases. Pediatrics. 1975;56:388-397.
6. Feldman S, Crout JD, Andrew ME. Incidence and natural history of chemically defined varicella-zoster virus hepatitis in children and adolescents. Scand J Inject Dis. 1997;29:33-36.
7. Muller I, Aepinus C, Beck R, et al. Noncutaneous varicella-zoster virus (VZV) infection with fatal liver failure in a child with acute lymphoblastic leukemia (ALL). Med Pediatr Oncol. 2001;37:145-147.
8. Dits H, Frans E, Wilmer A, et al. Varicella-zoster virus infection associated with acute liver failure. Clin Infect Dis. 1998;27:209-210.
9. Os I, Strom EH, Stenehjem A, et al. Varicella infection in a renal transplant recipient associated with abdominal pain, hepatitis, and glomerulonephritis. Scand J Urol Nephrol. 2001;35:330-333.
10. Stemmer SM, Kinsman K, Tellschow S, et al. Fatal noncutaneous visceral infection with varicella-zoster virus in a patient with lymphoma after autologous bone marrow transplantation. Clin Infect Dis. 1993;16: 497-499.
11. Anderson DR, Schwartz J, Hunter NJ, et al. Varicella hepatitis: a fatal case in a previously healthy, immunocompetent adult. Report of a case, autopsy, and review of the literature. Arch Intern Med. 1994;154:2101-2106.
12. Vartian CV. Varicella-zoster virus infection associated with acute liver failure. Clin Infect Dis. 1999;28:412-413.
13. Kavaliotis J, Loukou I, Trachana M, et al. Outbreak of varicella in a pediatric oncology unit. Med Pediatr Oncol. 1998;31:166-169.
14. Case records of the Massachusetts General Hospital, weekly clinicopathological exercises. Case 25-1988. Back and abdominal pain followed by disseminated intravascular coagulation in a five-year-old boy with leukemia in remission. N Engl J Med. 1988;318:1669-1679.
15. Grant RM, Weitzman SS, Sherman CG, et al. Fulminant disseminated varicella zoster virus infection without skin involvement. J Clin Virol. 2002;24:7-12.
16. Srugo I, Israele V, Wittek AE, et al. Clinical manifestations of varicella-zoster virus infections in human immunodeficiency virus-infected children. Am J Dis Child. 1993;147:742-745.
17. Ishizaki Y, Tezuka J, Ohga S, et al. Quantification of circulating varicella zoster virus-DNA for the early diagnosis of visceral varicella. J Infect. 2003;47:133-138.
18. Burnett I. Immunoglobulin should be given if steroid dosage was ≥0.5 mg/kg/day in preceding three months. Br Med J. 1995;310:327.
19. Varicella zoster immune globulin for the prevention of chickenpox. MMWR. 1984;33:84-90, 95-100.
20. Prevention of varicella. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR. 1996;45:1-43.
21. Camitta B, Chusid MJ, Starshak RJ, et al. Use of irradiated lymphocytes from immune donors for treatment of disseminated varicella. J Pediatr. 1994;124:593-596.