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Volumn 404, Issue 1, 2011, Pages 541-545

Identification and biological activities of a new antiangiogenic small molecule that suppresses mitochondrial reactive oxygen species

Author keywords

Angiogenesis; Cell based screening; Mitochondrial ROS; YCG063

Indexed keywords

ANGIOGENESIS INHIBITOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VASCULOTROPIN; YCG 063;

EID: 78650908301     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.12.022     Document Type: Article
Times cited : (17)

References (14)
  • 1
    • 70549092785 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species regulate hypoxic signaling
    • Hamanaka R.B., Chandel N.S. Mitochondrial reactive oxygen species regulate hypoxic signaling. Curr. Opin. Cell Biol. 2009, 21:894-899.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 894-899
    • Hamanaka, R.B.1    Chandel, N.S.2
  • 3
    • 77951241278 scopus 로고    scopus 로고
    • Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing
    • Jung H.J., Shim J.S., Lee J., Song Y.M., Park K.C., Choi S.H., Kim N.D., Yoon J.H., Mungai P.T., Schumacker P.T., Kwon H.J. Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing. J. Biol. Chem. 2010, 285:11584-11595.
    • (2010) J. Biol. Chem. , vol.285 , pp. 11584-11595
    • Jung, H.J.1    Shim, J.S.2    Lee, J.3    Song, Y.M.4    Park, K.C.5    Choi, S.H.6    Kim, N.D.7    Yoon, J.H.8    Mungai, P.T.9    Schumacker, P.T.10    Kwon, H.J.11
  • 4
    • 34250745912 scopus 로고    scopus 로고
    • The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production
    • Bell E.L., Klimova T.A., Eisenbart J., Moraes C.T., Murphy M.P., Budinger G.R., Chandel N.S. The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production. J. Cell Biol. 2007, 177:1029-1036.
    • (2007) J. Cell Biol. , vol.177 , pp. 1029-1036
    • Bell, E.L.1    Klimova, T.A.2    Eisenbart, J.3    Moraes, C.T.4    Murphy, M.P.5    Budinger, G.R.6    Chandel, N.S.7
  • 5
    • 0034021690 scopus 로고    scopus 로고
    • Hypoxia, clonal selection, and the role of HIF-1 in tumor progression
    • Semenza G.L. Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Crit. Rev. Biochem. Mol. Biol. 2000, 35:71-103.
    • (2000) Crit. Rev. Biochem. Mol. Biol. , vol.35 , pp. 71-103
    • Semenza, G.L.1
  • 7
    • 1242338653 scopus 로고    scopus 로고
    • High-content profiling of drug-drug interactions: cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazole
    • Giuliano K.A. High-content profiling of drug-drug interactions: cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazole. J. Biomol. Screen. 2003, 8:125-135.
    • (2003) J. Biomol. Screen. , vol.8 , pp. 125-135
    • Giuliano, K.A.1
  • 8
    • 7044227922 scopus 로고    scopus 로고
    • Quantification of the proliferation index of human dermal fibroblast cultures with the ArrayScan high-content screening reader
    • Gasparri F., Mariani M., Sola F., Galvani A. Quantification of the proliferation index of human dermal fibroblast cultures with the ArrayScan high-content screening reader. J. Biomol. Screen. 2004, 9:232-243.
    • (2004) J. Biomol. Screen. , vol.9 , pp. 232-243
    • Gasparri, F.1    Mariani, M.2    Sola, F.3    Galvani, A.4
  • 9
    • 77955569446 scopus 로고    scopus 로고
    • R-(-)-beta-O-methylsynephrine, a natural product, inhibits VEGF-induced angiogenesis in vitro and in vivo
    • Kim N.H., Pham N.B., Quinn R.J., Kwon H.J. R-(-)-beta-O-methylsynephrine, a natural product, inhibits VEGF-induced angiogenesis in vitro and in vivo. Biochem. Biophys. Res. Commun. 2010, 399:20-23.
    • (2010) Biochem. Biophys. Res. Commun. , vol.399 , pp. 20-23
    • Kim, N.H.1    Pham, N.B.2    Quinn, R.J.3    Kwon, H.J.4
  • 10
    • 74249098292 scopus 로고    scopus 로고
    • NBBA, a synthetic small molecule, inhibits TNF-alpha-induced angiogenesis by suppressing the NF-kappaB signaling pathway
    • Kim N.H., Jung H.J., Shibasaki F., Kwon H.J. NBBA, a synthetic small molecule, inhibits TNF-alpha-induced angiogenesis by suppressing the NF-kappaB signaling pathway. Biochem. Biophys. Res. Commun. 2010, 391:1500-1505.
    • (2010) Biochem. Biophys. Res. Commun. , vol.391 , pp. 1500-1505
    • Kim, N.H.1    Jung, H.J.2    Shibasaki, F.3    Kwon, H.J.4
  • 13
    • 77955493467 scopus 로고    scopus 로고
    • 2+/calmodulin antagonist HBC inhibits angiogenesis and down-regulates hypoxia-inducible factor
    • 2+/calmodulin antagonist HBC inhibits angiogenesis and down-regulates hypoxia-inducible factor. J. Biol. Chem. 2010, 285:25867-25874.
    • (2010) J. Biol. Chem. , vol.285 , pp. 25867-25874
    • Jung, H.J.1    Kim, J.H.2    Shim, J.S.3    Kwon, H.J.4
  • 14
    • 33644780111 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha
    • Kong X., Lin Z., Liang D., Fath D., Sang N., Caro J. Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha. Mol. Cell. Biol. 2006, 26:2019-2028.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2019-2028
    • Kong, X.1    Lin, Z.2    Liang, D.3    Fath, D.4    Sang, N.5    Caro, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.