Screening of newborn infants for cholestatic hepatobiliary disease with tandem mass spectrometry

British Medical Journal

Volumn 319, Issue 7208, 1999, Pages 471-477

  Mushtaq, Imran ^a   Logan, Stuart ^d   Morris, Michael ^b   Johnson, Andrew W ^a   Wade, Angie M ^d   Kelly, Deirdre ^c   Clayton, Peter T ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MICROMASS UK LTD   (United Kingdom)

^c BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; BILE ACID CONJUGATE;

ARTICLE; BABY; BILE DUCT ATRESIA; BLOOD ANALYSIS; HUMAN; NEWBORN; NEWBORN SCREENING; OBSTRUCTIVE JAUNDICE; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

AGE FACTORS; BILE ACIDS AND SALTS; BILIARY ATRESIA; BILIARY TRACT DISEASES; CHOLESTASIS; FEASIBILITY STUDIES; HEPATITIS; HUMANS; INFANT; INFANT, NEWBORN; MASS SPECTROMETRY; NEONATAL SCREENING; REGRESSION ANALYSIS; SENSITIVITY AND SPECIFICITY;

EID: 0033592220     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. 1 Winfield CR, MacFaul R. Clinical study of prolonged jaundice in breast and bottle fed babies. Arch Dis Child 1978;53:506-7.
2. 2 Kelly DA, Stanton A. Jaundice in babies: implications for community screening for biliary atresia. BMJ 1995;310:1172-3.
3. 3 Dick MC, Mowat AP. Hepatitis syndrome infancy - an epidemiological survey with 10 year follow-up. Arch Dis Child 1985;60:512-6.
4. 4 Mathew PM, Wharton BA. Investigation and management of neonatal jaundice, a problem orientated case record. Arch Dis Child 1981;36:949-53.
5. 5 Mowat AP, Davidson LL, Dick MC. Earlier identification of biliary atresia and hepatobiliary disease: selective screening in the third week of life. Arch Dis Child 1995;72:90-2.
6. 6 Mieli-Vergani G, Howard ER, Portmann B, Mowat AP. Late referral for biliary atresia: missed opportunities for effective surgery. Lancet 1989;i:121-3.
7. 7 DeConti RW, Craver RD, Willis GW, Hill CB, Hayes DH, Arensman RM. Extrahepatic biliary atresia from diagnosis to liver transplantation. Pediatr Surg Int 1992;7:737-40.
8. 8 Ohi R, Nio M, Chiha T, Endo N, Goto M, Ibrahim M. Long-term follow-up after surgery for patients with biliary atresia. J Pediatr Surg 1990;25:442-5.
9. 9 McNinch AW, Tripp JH. Haemorrhagic disease of the newborn in the British Isles: two year prospective study. BMJ 1991;303:1105-9.
10. 10 Logan S, Stanton A. Screening for biliary atresia. Lancet 1993;342:256.
11. 11 MacKiernan PJ. Biliary atresia. British Paediatric Surveillance Unit Quarterly Bulletin 1995;4:3.
12. 12 Raslied MS, Bucknall MP, Little D, Awad A, Jacob M, Alamoudi M, et al. Screening blood spots for inborn errors of metabolism by electrospray tandem mass spectrometry with a microplate batch process and a computer algorithm for automated flagging of abnormal profiles. Clin Chem 1997;13:1129-41.
13. 13 Mills K, Mushtaq I, Johnson AW, Whitfield P, Clayton PT. A method for the quantitation of conjugated bile acids in dried blood spots using electrospray ionization-mass spectrometry. Pediatr Res 1998;43:361-8.
14. 14 Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Diagnosta Radiol 1982;113:29-36.
15. 15 Hennekens CH, Buring JE. Epidemiology in medicine. 1st ed. Boston: Little, Brown, 1987.
16. 16 Tazawa Y, Yamada M, Nakagawa M, Konno T, Tada K. Serum bile acid patterns determined by an enzymatic method and high-performance liquid chromatography in young infants with cholestasis. J Pediatr Gastroenterol Nutr 1984;3:394-401.
17. 17 Javitt NB, Keating JP, Grand RJ, Harris RC. Serum bile acid patterns in neonatal hepatitis and extrahepatic biliary atresia. J Pediatr 1977;90:736-9.
18. 18 Matsui A, Fujimoto T, Takazawa Y, Okaniwa M, Kamoshita S. Serum bile acid levels in patients with extrahepatic biliary atresia and neonatal hepatitis during the first 10 days of life. J Pediatr 1985;107:255-7.
19. 19 Matsui A, Sasaki N, Arakawa Y, Ishikawa T, Momoya T, Kasano T, et al. Neonatal mass screening for biliary atresia. Screening 1993;2:201-9.
20. 20 Barries S, Berkowitz G, Hitschowitz BI, Wirtschafter, Cassady G. Postnatal physiologic hypercholaemia in both premature and full-term infants. J Clin Invest 1981;68:775-82.
21. 21 Senger H, Boehm G, Beyreiss K, Braun W. Bile acids in the serum and duodenal content of newborn infants of different classification. Biomed Biochim Acta 1986;45:931-9.