Contribution of IPS-1 to polyI:C-induced cytokine production in conjunctival epithelial cells

Biochemical and Biophysical Research Communications

Volumn 404, Issue 1, 2011, Pages 419-423

  Ueta, Mayumi ^a,b   Kawai, Taro ^c   Yokoi, Norihiko ^a   Akira, Shizuo ^c   Kinoshita, Shigeru ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b DOSHISHA UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Conjunctival epithelium; IPS 1; MDA5; PolyI:C; RIG I; TLR3

Indexed keywords

ADAPTOR PROTEIN; CELL PROTEIN; CMPK2 PROTEIN; CYTOKINE; EYE DROPS; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IFI203 PROTEIN; IFI44 PROTEIN; IIGP2 PROTEIN; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5; MESSENGER RNA; MX1 PROTEIN; MX2 PROTEIN; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN IPS 1; RANTES; RETINOIC ACID INDUCIBLE PROTEIN I; RSAD2 PROTEIN; RTP4 PROTEIN; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONJUNCTIVA EPITHELIUM; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPITHELIUM CELL; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IN VIVO STUDY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CONJUNCTIVA; CYTOKINES; DEAD-BOX RNA HELICASES; EPITHELIAL CELLS; EPITHELIUM; GENE EXPRESSION; HUMANS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; POLY I-C; TOLL-LIKE RECEPTOR 3; UP-REGULATION;

MURINAE; MUS;

EID: 78650872269     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.11.136     Document Type: Article

References (28)

1. Kawai T., Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int. Immunol. 2009, 21:317-337.
2. Ueta M., Hamuro J., Kiyono H., Kinoshita S. Triggering of TLR3 by polyI:C in human corneal epithelial cells to induce inflammatory cytokines. Biochem. Biophys. Res. Commun. 2005, 331:285-294.
3. Ueta M., Kinoshita S. Innate immunity of the ocular surface. Brain Res. Bull. 2010, 81:219-228.
4. Ueta M., Kinoshita S. Ocular surface inflammation mediated by innate immunity. Eye Contact Lens 2010, 36:269-281.
5. Ueta M., Mizushima K., Yokoi N., Naito Y., Kinoshita S. Gene-expression analysis of polyI:C-stimulated primary human conjunctival epithelial cells. Br. J. Ophthalmol. 2010.
6. Kojima K., Ueta M., Hamuro J., Hozono Y., Kawasaki S., Yokoi N., et al. Human conjunctival epithelial cells express functional Toll-like receptor 5. Br. J. Ophthalmol. 2008, 92:411-416.
7. Ueta M., Mizushima K., Yokoi N., Naito Y., Kinoshita S. Expression of the interleukin-4 receptor alpha in human conjunctival epithelial cells. Br. J. Ophthalmol. 2010, 94:1239-1243.
8. Ueta M., Mizushima K., Yokoi N., Naito Y., Kinoshita S. Gene-expression analysis of polyI:C-stimulated primary human conjunctival epithelial cells. Br J Ophthalmol 2010.
9. Kawai T., Takahashi K., Sato S., Coban C., Kumar H., Kato H., et al. IPS-1, an adaptor triggering RIG-I- and MDA5-mediated type I interferon induction. Nat. Immunol. 2005, 6:981-988.
10. Ueta M., Uematsu S., Akira S., Kinoshita S. Toll-like receptor 3 enhances late-phase reaction of experimental allergic conjunctivitis. J. Allergy Clin. Immunol. 2009, 123:1187-1189.
11. Lai Y., Di Nardo A., Nakatsuji T., Leichtle A., Yang Y., Cogen A.L., et al. Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury. Nat. Med. 2009, 15:1377-1382.
12. Torres D., Dieudonne A., Ryffel B., Vilain E., Si-Tahar M., Pichavant M., et al. Double-stranded RNA exacerbates pulmonary allergic reaction through TLR3: implication of airway epithelium and dendritic cells. J. Immunol. 2010, 185:451-459.
13. Hirata Y., Broquet A.H., Menchen L., Kagnoff M.F. Activation of innate immune defense mechanisms by signaling through RIG-I/IPS-1 in intestinal epithelial cells. J. Immunol. 2007, 179:5425-5432.
14. Kumar H., Koyama S., Ishii K.J., Kawai T., Akira S. Cutting edge: cooperation of IPS-1- and TRIF-dependent pathways in poly IC-enhanced antibody production and cytotoxic T cell responses. J. Immunol. 2008, 180:683-687.
15. Shaveta G., Shi J., Chow V.T., Song J. Structural characterization reveals that viperin is a radical S-adenosyl-l-methionine (SAM) enzyme. Biochem. Biophys. Res. Commun. 2010, 391:1390-1395.
16. Jin H.K., Yoshimatsu K., Takada A., Ogino M., Asano A., Arikawa J., et al. Mouse Mx2 protein inhibits hantavirus but not influenza virus replication. Arch. Virol. 2001, 146:41-49.
17. Xu Y., Johansson M., Karlsson A. Human UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondria. J. Biol. Chem. 2008, 283:1563-1571.
18. Miyairi I., Tatireddigari V.R., Mahdi O.S., Rose L.A., Belland R.J., Lu L., et al. The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection. J. Immunol. 2007, 179:1814-1824.
19. Hallen L.C., Burki Y., Ebeling M., Broger C., Siegrist F., Oroszlan-Szovik K., et al. Antiproliferative activity of the human IFN-alpha-inducible protein IFI44. J. Interferon Cytokine Res. 2007, 27:675-680.
20. Farber J.M. Mig and IP-10: CXC chemokines that target lymphocytes. J. Leukoc. Biol. 1997, 61:246-257.
21. Klunker S., Trautmann A., Akdis M., Verhagen J., Schmid-Grendelmeier P., Blaser K., et al. A second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis release IFN-gamma-inducible protein 10, monokine induced by IFN-gamma, and IFN-gamma-inducible alpha-chemoattractant for T cell chemotaxis toward epidermis in atopic dermatitis. J. Immunol. 2003, 171:1078-1084.
22. Ying S., O'Connor B., Ratoff J., Meng Q., Fang C., Cousins D., et al. Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease. J. Immunol. 2008, 181:2790-2798.
23. Horisberger M.A. Interferons, Mx genes, and resistance to influenza virus. Am. J. Respir. Crit. Care Med. 1995, 152:S67-S71.
24. Mondini M., Costa S., Sponza S., Gugliesi F., Gariglio M., Landolfo S. The interferon-inducible HIN-200 gene family in apoptosis and inflammation: implication for autoimmunity. Autoimmunity 2010, 43:226-231.
25. Saito H., Kubota M., Roberts R.W., Chi Q., Matsunami H. RTP family members induce functional expression of mammalian odorant receptors. Cell 2004, 119:679-691.
26. Prehaud C., Megret F., Lafage M., Lafon M. Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon. J. Virol. 2005, 79:12893-12904.
27. Gros E., Bussmann C., Bieber T., Forster I., Novak N. Expression of chemokines and chemokine receptors in lesional and nonlesional upper skin of patients with atopic dermatitis. J. Allergy Clin. Immunol. 2009.
28. Cavassani K.A., Ishii M., Wen H., Schaller M.A., Lincoln P.M., Lukacs N.W., et al. TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events. J. Exp. Med. 2008, 205:2609-2621.