메뉴 건너뛰기




Volumn 31, Issue SUPPL. 1, 2011, Pages 13-17

How to assess liver fibrosis in chronic hepatitis C: Serum markers or transient elastography vs. liver biopsy?

Author keywords

FibroScan; Liver biopsy; Liver fibrosis; Non invasive; Serum biomarkers; Transient elastography

Indexed keywords

ASPARTIC ACID; BIOLOGICAL MARKER;

EID: 78650852335     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2010.02380.x     Document Type: Article
Times cited : (58)

References (51)
  • 1
    • 17544367989 scopus 로고    scopus 로고
    • Which patients with hepatitis C develop liver complications?
    • Khan MH, Farrell GC, Byth K, et al. Which patients with hepatitis C develop liver complications? Hepatology 2000; 31: 513-20.
    • (2000) Hepatology , vol.31 , pp. 513-20
    • Khan, M.H.1    Farrell, G.C.2    Byth, K.3
  • 2
    • 0036829652 scopus 로고    scopus 로고
    • Fibrosis and disease progression in hepatitis C
    • Marcellin P, Asselah T, Boyer N. Fibrosis and disease progression in hepatitis C. Hepatology 2002; 36 (Suppl. 1): S47-56.
    • (2002) Hepatology , vol.36 , Issue.SUPPL. 1
    • Marcellin, P.1    Asselah, T.2    Boyer, N.3
  • 3
    • 74949133886 scopus 로고    scopus 로고
    • Antifibrotic therapies - emerging biomarkers as treatment end points
    • Talwalkar JA. Antifibrotic therapies - emerging biomarkers as treatment end points. Nat Rev Gastroenterol Hepatol 2010; 7: 59-61.
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , pp. 59-61
    • Talwalkar, J.A.1
  • 4
    • 0029778988 scopus 로고    scopus 로고
    • An algorithm for the grading of activity in chronic hepatitis C. The METAVIR cooperative study group
    • Bedossa P, Poynard T. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR cooperative study group. Hepatology 1996; 24: 289-93.
    • (1996) Hepatology , vol.24 , pp. 289-93
    • Bedossa, P.1    Poynard, T.2
  • 5
    • 0029039362 scopus 로고
    • Histological grading and staging of chronic hepatitis
    • Ishak K, Baptista A, Bianchi L, et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995; 22: 696-9.
    • (1995) J Hepatol , vol.22 , pp. 696-9
    • Ishak, K.1    Baptista, A.2    Bianchi, L.3
  • 6
    • 0036792679 scopus 로고    scopus 로고
    • Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection
    • Regev A, Berho M, Jeffers LJ, et al. Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection. Am J Gastroenterol 2002; 97: 2614-8.
    • (2002) Am J Gastroenterol , vol.97 , pp. 2614-8
    • Regev, A.1    Berho, M.2    Jeffers, L.J.3
  • 7
    • 0345017740 scopus 로고    scopus 로고
    • Sampling variability of liver fibrosis in chronic hepatitis C
    • Bedossa P, Dargère D, Paradis V. Sampling variability of liver fibrosis in chronic hepatitis C. Hepatology 2003; 38: 1449-57.
    • (2003) Hepatology , vol.38 , pp. 1449-57
    • Bedossa, P.1    Dargère, D.2    Paradis, V.3
  • 8
    • 0042671303 scopus 로고    scopus 로고
    • Impact of liver biopsy size on histological evaluation of chronic viral hepatitis
    • J Hepatol
    • Colloredo G, Guido M, Sonzogni A, et al. Impact of liver biopsy size on histological evaluation of chronic viral hepatitis: the smaller the sample, the milder the disease. J Hepatol 2003; 39: 239-44.
    • (2003) the smaller the sample, the milder the disease , vol.39 , pp. 239-44
    • Colloredo, G.1    Guido, M.2    Sonzogni, A.3
  • 9
    • 0028234491 scopus 로고
    • Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. The French METAVIR Cooperative Study Group
    • Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. The French METAVIR Cooperative Study Group. Hepatology 1994; 20: 15-20.
    • (1994) Hepatology , vol.20 , pp. 15-20
  • 10
    • 0030297138 scopus 로고    scopus 로고
    • Intra-observer and inter-observer variation in the histopathological assessment of chronic viral hepatitis
    • Goldin RD, Goldin JG, Burt AD, et al. Intra-observer and inter-observer variation in the histopathological assessment of chronic viral hepatitis. J Hepatol 1996; 25: 649-54.
    • (1996) J Hepatol , vol.25 , pp. 649-54
    • Goldin, R.D.1    Goldin, J.G.2    Burt, A.D.3
  • 12
    • 0032717037 scopus 로고    scopus 로고
    • Pain experienced during percutaneous liver biopsy
    • Castera L, Negre I, Samii K, et al. Pain experienced during percutaneous liver biopsy. Hepatology 1999; 30: 1529-30.
    • (1999) Hepatology , vol.30 , pp. 1529-30
    • Castera, L.1    Negre, I.2    Samii, K.3
  • 13
    • 0342936460 scopus 로고    scopus 로고
    • Patient-administered nitrous oxide/oxygen inhalation provides safe and effective analgesia for percutaneous liver biopsy
    • Am J Gastroenterol
    • Castera L, Negre I, Samii K, et al. Patient-administered nitrous oxide/oxygen inhalation provides safe and effective analgesia for percutaneous liver biopsy: a randomized placebo-controlled trial. Am J Gastroenterol 2001; 96: 1553-7.
    • (2001) a randomized placebo-controlled trial , vol.96 , pp. 1553-7
    • Castera, L.1    Negre, I.2    Samii, K.3
  • 14
    • 34548304725 scopus 로고    scopus 로고
    • Evidence for a role of nonalcoholic steatohepatitis in hepatitis C
    • Hepatology
    • Bedossa P, Moucari R, Chelbi E, et al. Evidence for a role of nonalcoholic steatohepatitis in hepatitis C: a prospective study. Hepatology 2007; 46: 380-7.
    • (2007) a prospective study , vol.46 , pp. 380-7
    • Bedossa, P.1    Moucari, R.2    Chelbi, E.3
  • 15
    • 0035192821 scopus 로고    scopus 로고
    • The role of liver biopsy in chronic hepatitis C
    • Saadeh S, Cammell G, Carey WD, et al. The role of liver biopsy in chronic hepatitis C. Hepatology 2001; 33: 196-200.
    • (2001) Hepatology , vol.33 , pp. 196-200
    • Saadeh, S.1    Cammell, G.2    Carey, W.D.3
  • 16
    • 77952305743 scopus 로고    scopus 로고
    • Non-invasive assessment of liver fibrosis
    • Lancet
    • Castera L, Pinzani M. Non-invasive assessment of liver fibrosis: are we ready? Lancet 2010; 375: 1419-20.
    • (2010) are we ready? , vol.375 , pp. 1419-20
    • Castera, L.1    Pinzani, M.2
  • 19
    • 42949130108 scopus 로고    scopus 로고
    • Diagnosis and quantitation of fibrosis
    • Manning DS, Afdhal NH. Diagnosis and quantitation of fibrosis. Gastroenterology 2008; 134: 1670-81.
    • (2008) Gastroenterology , vol.134 , pp. 1670-81
    • Manning, D.S.1    Afdhal, N.H.2
  • 20
    • 77954025334 scopus 로고    scopus 로고
    • Biopsy and non-invasive methods for the diagnosis of liver fibrosis
    • Gut
    • Castera L, Pinzani M. Biopsy and non-invasive methods for the diagnosis of liver fibrosis: does it take two to tango? Gut 2010; 59: 861-6.
    • (2010) does it take two to tango? , vol.59 , pp. 861-6
    • Castera, L.1    Pinzani, M.2
  • 21
    • 41349094999 scopus 로고    scopus 로고
    • Performance of transient elastography for the staging of liver fibrosis
    • Gastroenterology
    • Friedrich-Rust M, Ong MF, Martens S, et al. Performance of transient elastography for the staging of liver fibrosis: a meta-analysis. Gastroenterology 2008; 134: 960-74.
    • (2008) a meta-analysis , vol.134 , pp. 960-74
    • Friedrich-Rust, M.1    Ong, M.F.2    Martens, S.3
  • 22
    • 38049125477 scopus 로고    scopus 로고
    • Meta-analyses of FibroTest diagnostic value in chronic liver disease
    • Poynard T, Morra R, Halfon P, et al. Meta-analyses of FibroTest diagnostic value in chronic liver disease. BMC Gastroenterol 2007; 7: 40.
    • (2007) BMC Gastroenterol , vol.7 , pp. 40
    • Poynard, T.1    Morra, R.2    Halfon, P.3
  • 23
    • 34548786091 scopus 로고    scopus 로고
    • Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis C-related fibrosis
    • Hepatology
    • Shaheen AA, Myers RP. Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis C-related fibrosis: a systematic review. Hepatology 2007; 46: 912-21.
    • (2007) a systematic review , vol.46 , pp. 912-21
    • Shaheen, A.A.1    Myers, R.P.2
  • 24
    • 12344309018 scopus 로고    scopus 로고
    • Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C
    • Castera L, Vergniol J, Foucher J, et al. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology 2005; 128: 343-50.
    • (2005) Gastroenterology , vol.128 , pp. 343-50
    • Castera, L.1    Vergniol, J.2    Foucher, J.3
  • 25
    • 78049485434 scopus 로고    scopus 로고
    • Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis
    • J Hepatol
    • Degos F, Perez P, Roche B, et al. Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study). J Hepatol 2010; 53: 1013-21.
    • (2010) a multicenter prospective study (the FIBROSTIC study) , vol.53 , pp. 1013-21
    • Degos, F.1    Perez, P.2    Roche, B.3
  • 26
    • 33644901827 scopus 로고    scopus 로고
    • Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C
    • Sebastiani G, Vario A, Guido M, et al. Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C. J Hepatol 2006; 44: 686-93.
    • (2006) J Hepatol , vol.44 , pp. 686-93
    • Sebastiani, G.1    Vario, A.2    Guido, M.3
  • 29
    • 73149088054 scopus 로고    scopus 로고
    • The combination of a blood test and FibroScan improves the non-invasive diagnosis of liver fibrosis
    • Boursier J, Vergniol J, Sawadogo A, et al. The combination of a blood test and FibroScan improves the non-invasive diagnosis of liver fibrosis. Liver Int 2009; 29: 1507-15.
    • (2009) Liver Int , vol.29 , pp. 1507-15
    • Boursier, J.1    Vergniol, J.2    Sawadogo, A.3
  • 30
    • 75349088230 scopus 로고    scopus 로고
    • Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C
    • Castera L, Sebastiani G, Le Bail B, et al. Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C. J Hepatol 2010; 52: 191-8.
    • (2010) J Hepatol , vol.52 , pp. 191-8
    • Castera, L.1    Sebastiani, G.2    Le Bail, B.3
  • 32
    • 11144355931 scopus 로고    scopus 로고
    • Intra-laboratory analytical variability of biochemical markers of fibrosis (Fibrotest) and activity (Actitest) and reference ranges in healthy blood donors
    • Imbert-Bismut F, Messous D, Thibaut V, et al. Intra-laboratory analytical variability of biochemical markers of fibrosis (Fibrotest) and activity (Actitest) and reference ranges in healthy blood donors. Clin Chem Lab Med 2004; 42: 323-33.
    • (2004) Clin Chem Lab Med , vol.42 , pp. 323-33
    • Imbert-Bismut, F.1    Messous, D.2    Thibaut, V.3
  • 33
    • 36749046969 scopus 로고    scopus 로고
    • Reproducibility of blood tests of liver fibrosis in clinical practice
    • Cales P, Veillon P, Konate A, et al. Reproducibility of blood tests of liver fibrosis in clinical practice. Clin Biochem 2008; 41: 10-8.
    • (2008) Clin Biochem , vol.41 , pp. 10-8
    • Cales, P.1    Veillon, P.2    Konate, A.3
  • 34
    • 3242798959 scopus 로고    scopus 로고
    • Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C
    • Poynard T, Munteanu M, Imbert-Bismut F, et al. Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C. Clin Chem 2004; 50: 1344-55.
    • (2004) Clin Chem , vol.50 , pp. 1344-55
    • Poynard, T.1    Munteanu, M.2    Imbert-Bismut, F.3
  • 35
    • 34247631059 scopus 로고    scopus 로고
    • Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease
    • Fraquelli M, Rigamonti C, Casazza G, et al. Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease. Gut 2007; 56: 968-73.
    • (2007) Gut , vol.56 , pp. 968-73
    • Fraquelli, M.1    Rigamonti, C.2    Casazza, G.3
  • 36
    • 55149113975 scopus 로고    scopus 로고
    • Reproducibility of liver stiffness measurement by ultrasonographic elastometry
    • Boursier J, Konate A, Gorea G, et al. Reproducibility of liver stiffness measurement by ultrasonographic elastometry. Clin Gastroenterol Hepatol 2008; 6: 1263-9.
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 1263-9
    • Boursier, J.1    Konate, A.2    Gorea, G.3
  • 39
    • 39549105171 scopus 로고    scopus 로고
    • Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage
    • Sagir A, Erhardt A, Schmitt M, et al. Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage. Hepatology 2007; 47: 592-5.
    • (2007) Hepatology , vol.47 , pp. 592-5
    • Sagir, A.1    Erhardt, A.2    Schmitt, M.3
  • 40
    • 39549115031 scopus 로고    scopus 로고
    • Acute viral hepatitis increases liver stiffness values measured by transient elastography
    • Arena U, Vizzutti F, Corti G, et al. Acute viral hepatitis increases liver stiffness values measured by transient elastography. Hepatology 2008; 47: 380-4.
    • (2008) Hepatology , vol.47 , pp. 380-4
    • Arena, U.1    Vizzutti, F.2    Corti, G.3
  • 41
    • 56149103873 scopus 로고    scopus 로고
    • Extrahepatic cholestasis increases liver stiffness (FibroScan) irrespective of fibrosis
    • Millonig G, Reimann FM, Friedrich S, et al. Extrahepatic cholestasis increases liver stiffness (FibroScan) irrespective of fibrosis. Hepatology 2008; 48: 1718-23.
    • (2008) Hepatology , vol.48 , pp. 1718-23
    • Millonig, G.1    Reimann, F.M.2    Friedrich, S.3
  • 42
    • 75349114937 scopus 로고    scopus 로고
    • Liver stiffness is directly influenced by central venous pressure
    • Millonig G, Friedrich S, Adolf S, et al. Liver stiffness is directly influenced by central venous pressure. J Hepatol 2010; 52: 206-10.
    • (2010) J Hepatol , vol.52 , pp. 206-10
    • Millonig, G.1    Friedrich, S.2    Adolf, S.3
  • 43
    • 0344586867 scopus 로고    scopus 로고
    • Liver biopsy size matters in chronic hepatitis
    • Hepatology
    • Scheuer PJ. Liver biopsy size matters in chronic hepatitis: bigger is better. Hepatology 2003; 38: 1356-8.
    • (2003) bigger is better , vol.38 , pp. 1356-8
    • Scheuer, P.J.1
  • 44
    • 12844282183 scopus 로고    scopus 로고
    • Sources of variability in histological scoring of chronic viral hepatitis
    • Rousselet MC, Michalak S, Dupre F, et al. Sources of variability in histological scoring of chronic viral hepatitis. Hepatology 2005; 41: 257-64.
    • (2005) Hepatology , vol.41 , pp. 257-64
    • Rousselet, M.C.1    Michalak, S.2    Dupre, F.3
  • 45
    • 78650843024 scopus 로고    scopus 로고
    • Non invasive methods for the evaluation of hepatic fibrosis/cirrhosis: an update, 2008. Available at
    • Non invasive methods for the evaluation of hepatic fibrosis/cirrhosis: an update, 2008. Available at
  • 46
    • 65449171953 scopus 로고    scopus 로고
    • Telaprevir and peginterferon with or without ribavirin for chronic HCV infection
    • Hezode C, Forestier N, Dusheiko G, et al. Telaprevir and peginterferon with or without ribavirin for chronic HCV infection. N Engl J Med 2009; 360: 1839-50.
    • (2009) N Engl J Med , vol.360 , pp. 1839-50
    • Hezode, C.1    Forestier, N.2    Dusheiko, G.3
  • 47
    • 77956268467 scopus 로고    scopus 로고
    • Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1)
    • Lancet
    • Kwo PY, Lawitz EJ, McCone J, et al. Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial. Lancet 2010; 376: 705-16.
    • (2010) an open-label, randomised, multicentre phase 2 trial , vol.376 , pp. 705-16
    • Kwo, P.Y.1    Lawitz, E.J.2    McCone, J.3
  • 48
    • 63549110422 scopus 로고    scopus 로고
    • Prospective evaluation of liver stiffness dynamics during and after peginterferon alpha-ribavirin treatment in patients with chronic hepatitis C (abstract)
    • Hézode C, Castéra L, Rosa I, et al. Prospective evaluation of liver stiffness dynamics during and after peginterferon alpha-ribavirin treatment in patients with chronic hepatitis C (abstract). Hepatology 2008; 48 (Suppl.): 849A.
    • (2008) Hepatology , vol.48 , Issue.SUPPL.
    • Hézode, C.1    Castéra, L.2    Rosa, I.3
  • 49
    • 46049100990 scopus 로고    scopus 로고
    • Magnetic resonance elastography for the noninvasive staging of liver fibrosis
    • Huwart L, Sempoux C, Vicaut E, et al. Magnetic resonance elastography for the noninvasive staging of liver fibrosis. Gastroenterology 2008; 135: 32-40.
    • (2008) Gastroenterology , vol.135 , pp. 32-40
    • Huwart, L.1    Sempoux, C.2    Vicaut, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.