Pathophysiology of carotid stenosis

Brain and Nerve

Volumn 62, Issue 12, 2010, Pages 1269-1275

  Yamazaki, Masako ^a   Uchiyama, Shinichiro ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Atherothrombosis; Embolism; Hemodynamic; Inflammation; Unstable plaque

Indexed keywords

C REACTIVE PROTEIN; CHEMOKINE;

ARTICLE; ATHEROSCLEROTIC PLAQUE; BRAIN INFARCTION; CAROTID ARTERY OBSTRUCTION; CELL MIGRATION; CELL PROLIFERATION; CYTOKINE RELEASE; DIABETES MELLITUS; DYSLIPIDEMIA; ENDOTHELIAL DYSFUNCTION; HEMODYNAMICS; HUMAN; HYPERTENSION; INFLAMMATORY CELL; PATHOPHYSIOLOGY; SMOOTH MUSCLE FIBER; THROMBOCYTE AGGREGATION; THROMBOEMBOLISM; THROMBOGENESIS;

BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CAROTID STENOSIS; CEREBRAL INFARCTION; CHEMOKINES; CYTOKINES; DIABETES MELLITUS; DIAGNOSTIC IMAGING; DYSLIPIDEMIAS; ENDARTERECTOMY, CAROTID; HUMANS; HYPERTENSION; RISK FACTORS; STENTS;

EID: 78650819819     PISSN: 18816096     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Ross R: Atherosclerosis - an inflammatory disease. N Engl J Med 340: 115-126, 1999
2. Libby P: Current concepts of the pathogenesis of the acute coronary syndromes. Circulation 104: 365-372, 2001
3. Vascular Lab 4: 398-403, 2007
4. Vascular Medicine 1: 123-131, 2005
5. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, et al: From vulnerable plaque to vulnerable patient: A call for new definition and risk assessment strategies: Part I. Circulation 108: 1664-1672, 2003 (Pubitemid 37243650)
6. Stary HC, Chandler AB, Dinsmore RE, Fuster V, Glagov S, et al: A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. Circulation 92: 1355-1374, 1995
7. Plaque erosion. Vascular Medicine 2: 81-86, 2006
8. Vascular Lab 4: 366-372, 2007
9. Redgrave JNE, Lovett JK, Gallagher PJ and Rothwell PM: Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic syndromes. The Oxford Plaque Study. Circulation. 113: 2320-2328, 2006
10. Pitt B, Byington RP, Furberg CD, Hunninghake DB, Mancini GB, et al; PREVENT Investigators: Effect of Amlodipine on the progression of atherosclerosis and the occurrence of clinical events. Circulation 102: 1503-1510, 2000
11. Mazzone T, Meyer PM, Feinstein SB, Davidson MH, Kondos GT, et al: Effect of pioglitazone compared with glimepiride on carotid intima-media thicknes in type 2 diabetes. JAMA 296: 2572-2581, 2006
12. Smilede TJ, Wissen S, Wollrsheim H, Kastelein JJP, Stalenhoef AFH: Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolaemia (ASAP): a prospective, randomised double-blind trial. Lancet 357: 577-581, 2001 (Pubitemid 32179609)
13. Crisby M, Nordin-Fredriksson G, Shah PK, Yano J, Zhu J, et al: Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotic plaques. Implications of plaque stabilization. Circulation 103: 926-933, 2001 (Pubitemid 32183796)
14. Katakami N, Kim YS, Kawamori R, Yamazaki Y: The phosphodiesterase inhibitor cilostazol induces regression of carotid atherosclerosis in subjectsi with type 2 diabetes mellitus. Principal results of the diabetic atherosclerosis prevention by cilostazol (DAPC) study: a randomized trial. Circulation 121: 2584-2591, 2010
15. Prati P, Tosetto A, Vanuzzo D, Bader G, Casaroli M, et al: Carotid intima media thickness and plaques can predict the occurrence of ischemic cerebrovascular events. Stroke 39: 2470-2476, 2008
16. Spagnoli LG, Mauriello A, Sangiorgi G, Fratoni S, Bonanno E, et al: Extracranial thrombotically active carotid plaque as a risk factor for ischemic stroke. JAMA 292: 1845-1852, 2004
17. Lamina C, Meisinger C, Heid IM, Lowell H, Rantner B, et al: Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up. Eur H J 27: 2580-2587, 2006
18. Brain Nerve 61: 1061-1068, 2009
19. Carr S, Farb A, Pearce WH, Virmani R, Yao JST: Atherosclerotic plaque rupture in symptomatic carotid artery stenosis. J Vasc Surg 23: 755-766, 1996 (Pubitemid 26159161)
20. Honda O, Sugiyama S, Kugiyama K, Fukushima H, Nakamura S, et al: Echolucent carotid plaques predict future coronary events in patients with coronary artery disease. J Am Coll Cardiol 43: 1177-1184, 2004 (Pubitemid 38452593)
21. Magyar MT, Szujszau Z, Balla J, Valikovics A, Kappelmayer J, et al: Early-onset carotid atherosclerosis is associated with increased intima-media thickness and elevated serum levels of inflammatory markers. Stroke 34: 58-63, 2003
22. Yamagami H, Kitagawa K, Nagai Y, Hougaku H, Sakaguchi M, et al: Higher levels of interleukin-6 are associated with lower echogenicity of carotid artery plaques. Stroke 35: 677-681, 2004
23. Hashimoto H, Kitagawa K, Kuwabara K, Hougaku H, Ohtsuki T, et al: Circulating adhesion molecules are associated with ultrasonic assessment of carotid plaques. Clinical Science 104: 521-527, 2003
24. Novo S. Basilli S, Tantillo R, Falco A, Davi V, et al: Soluble CD40L and cardiovascular risk in asymptomatic low-grade carotid stenosis. Stroke 36: 673-675, 2005 (Pubitemid 40344177)
25. Koyama H, Maeno T, Fukumoto S, Shoji T, Yamane T, et al: Platelet p-selectin expression is associated with atherosclerotic wall thickness in carotid artery in humans. Circulation 108: 524-529, 2003
26. Ramsis N, El-Hawary AA, Ismali E: Relation between carotid intima-media thickness, platelet surface activation and endothelial markers. Haemostasis 28: 268-275, 1998
27. Shimizu M, Kohara S, Yamamoto M, Ando Y, Haida M, et al: Significant relationship between platelet activation and intima-media thickness of the carotid artery in patients with ischemic cerebrovascular disease. Thromb Res 117: 647-652, 2006