Menin controls the concentration of retinoblastoma protein

Cell Cycle

Volumn 10, Issue 1, 2011, Pages 166-168

  Ivo, Dina ^a,b   Corset, Laetitia ^a,b   Desbourdes, Laura ^a   Gaudray, Patrick ^a,b   Weber, Günther ^a,b  

^a UNIVERSITÉ DE TOURS   (France)

^b CNRS   (France)

Author keywords

Menin; Phosphorylation; Posttranscriptional control; RB1; Tumor suppressor gene

Indexed keywords

METHIONINE; PROTEIN MDM2; RETINOBLASTOMA PROTEIN; SMALL INTERFERING RNA;

ARTICLE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL GROWTH; CHROMATIN; HUMAN; MULTIPLE ENDOCRINE NEOPLASIA; NONHUMAN; POSTTRANSCRIPTIONAL GENE SILENCING; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

MUS;

EID: 78650818077     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.1.14447     Document Type: Article

References (12)

1. Gaudray P, Weber G. Genetic background of MEN1: from genetic homogeneity to functional diversity. Adv Exp Med Biol 2009; 668:17-26.
2. Poisson A, Zablewska B, Gaudray P. Menin interacting proteins as clues toward the understanding of multiple endocrine neoplasia type 1. Cancer Lett 2003; 189:1-10.
3. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
4. Loffler KA, et al. Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice. Oncogene 2007; 26:4009-17.
5. Matoso A, Zhou Z, Hayama R, Flesken-Nikitin A, Nikitin AY. Cell lineage-specific interactions between Men1 and Rb in neuroendocrine neoplasia. Carcinogenesis 2008; 29:620-8.
6. INK4c. Proc Natl Acad Sci USA 2005; 102:14659-64.
7. Milne TA, et al. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proc Natl Acad Sci USA 2005; 102:749-54.
8. Hussein N, et al. Reconstituted expression of menin in Men1-deficient mouse Leydig tumour cells induces cell cycle arrest and apoptosis. Eur J Cancer 2007; 43:402-14.
9. Zablewska B, Bylund L, Mandic SA, Fromaget M, Gaudray P, Weber G. Transcription regulation of the multiple endocrine neoplasia type 1 gene in human and mouse. J Clin Endocrinol Metab 2003; 88:3845-51.
10. Bazzi W, et al. MEN1 missense mutations impair sensitization to apoptosis induced by wild-type menin in endocrine pancreatic tumor cells. Gastroenterology 2008; 135:1698-709.
11. Wang YV, Leblanc M, Wade M, Jochemsen AG, Wahl GM. Increased radioresistance and accelerated B cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA-damage-activated kinases. Cancer Cell 2009; 16:33-43.
12. Miwa S, et al. Mdm2-mediated pRB downregulation is involved in carcinogenesis in a p53-independent manner. Biochem Biophys Res Commun 2006; 340:54-61. (Pubitemid 41827647)