Detection of multiple strains of Mycobacterium tuberculosis using MIRU-VNTR in patients with pulmonary tuberculosis in Kampala, Uganda

BMC Infectious Diseases

Volumn 10, Issue , 2010, Pages

  Dickman, Katherine R ^a,b   Nabyonga, Lydia ^b   Kateete, David P ^b   Katabazi, Fred A ^b   Asiimwe, Benon B ^b   Mayanja, Harriet K ^b   Okwera, Alphonse ^c   Whalen, Christopher ^d   Joloba, Moses L ^b  

^a BOSTON MEDICAL CENTER   (United States)

^b MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES   (Uganda)

^c MULAGO NATIONAL REFERRAL HOSPITAL   (Uganda)

^d UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHAMBUTOL; GENOMIC DNA; ISONIAZID; PYRAZINAMIDE; RIFAMPICIN; STREPTOMYCIN; BACTERIAL DNA;

ADULT; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; BACTERIUM DETECTION; CONTROLLED STUDY; DNA EXTRACTION; FEMALE; HUMAN; INCIDENCE; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIAL INTERSPERSED REPETITIVE UNIT VARIABLE NUMBER TANDEM REPEATS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLYMERASE CHAIN REACTION; PREVALENCE; TREATMENT RESPONSE; UGANDA; BACTERIUM IDENTIFICATION; CLASSIFICATION; DNA SEQUENCE; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MOLECULAR EPIDEMIOLOGY; VARIABLE NUMBER OF TANDEM REPEAT;

ADULT; BACTERIAL TYPING TECHNIQUES; DNA, BACTERIAL; FEMALE; HUMANS; MALE; MINISATELLITE REPEATS; MOLECULAR EPIDEMIOLOGY; MYCOBACTERIUM TUBERCULOSIS; PREVALENCE; SEQUENCE ANALYSIS, DNA; TUBERCULOSIS, PULMONARY; UGANDA;

EID: 78650817032     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-10-349     Document Type: Article

References (22)

1. Balasubramanian V, Wiegeshaus EH, Taylor BT, Smith DW. Pathogenesis of tuberculosis: pathway to apical localization. Tubercle and Lung Disease 1994, 75(3):168-178. 10.1016/0962-8479(94)90002-7, 7919306.
2. Daley CL. Molecular Epidemiology: A Tool for Understanding Control of Tuberculosis Transmission. Clinics in Chest Medicine 2005, 26(2):217-231. 10.1016/j.ccm.2005.02.005, 15837107.
3. DeRiemer K, Daley CL. Tuberculosis transmission based on molecular epidemiologic research. Semin Respir Crit Care Med 2004, 25(3):297-306. 10.1055/s-2004-829502, 16088471.
4. Fine PE, Small PM. Exogenous reinfection in tuberculosis. N Engl J Med 1999, 341(16):1226-1227. 10.1056/NEJM199910143411609, 10519901.
5. Sonnenberg P, Murray J, Glynn JR, Shearer S, Kambashi B, Godfrey-Faussett P. HIV-1 and recurrence, relapse, and reinfection of tuberculosis after cure: a cohort study in South African mineworkers. Lancet 2001, 358(9294):1687-1693. 10.1016/S0140-6736(01)06712-5, 11728545.
6. de Boer AS, Kremer K, Borgdorff MW, de Haas PEW, Heersma HF, van Soolingen D. Genetic Heterogeneity in Mycobacterium tuberculosis Isolates Reflected in IS6110 Restriction Fragment Length Polymorphism Patterns as Low-Intensity Bands. J Clin Microbiol 2000, 38(12):4478-4484. 87624, 11101583.
7. Chaves F, Dronda F, Alonso-Sanz M, Noriega AR. Evidence of exogenous reinfection and mixed infection with more than one strain of Mycobacterium tuberculosis among Spanish HIV-infected inmates. AIDS 1999, 13(5):615-620. 10.1097/00002030-199904010-00011, 10203387.
8. Garcia de Viedma D, Alonso Rodriguez N, Andres S, Ruiz Serrano MJ, Bouza E. Characterization of clonal complexity in tuberculosis by mycobacterial interspersed repetitive unit-variable-number tandem repeat typing. J Clin Microbiol 2005, 43(11):5660-5664. 10.1128/JCM.43.11.5660-5664.2005, 1287844, 16272501.
9. Richardson M, Carroll NM, Engelke E, Van Der Spuy GD, Salker F, Munch Z, Gie RP, Warren RM, Beyers N, Van Helden PD. Multiple Mycobacterium tuberculosis strains in early cultures from patients in a high-incidence community setting. J Clin Microbiol 2002, 40(8):2750-2754. 10.1128/JCM.40.8.2750-2754.2002, 120639, 12149324.
10. Shamputa IC, Jugheli L, Sadradze N, Willery E, Portaels F, Supply P, Rigouts L. Mixed infection and clonal representativeness of a single sputum sample in tuberculosis patients from a penitentiary hospital in Georgia. Respir Res 2006, 7:99. 10.1186/1465-9921-7-99, 1538999, 16846493.
11. Warren RM, Victor TC, Streicher EM, Richardson M, Beyers N, van Pittius NCG, van Helden PD. Patients with Active Tuberculosis often Have Different Strains in the Same Sputum Specimen. Am J Respir Crit Care Med 2004, 169(5):610-614. 10.1164/rccm.200305-714OC, 14701710.
12. de Viedma Darío G, Marín M, Ruiz Serrano María J, Alcalá L, Bouza E. Polyclonal and Compartmentalized Infection by Mycobacterium tuberculosis in Patients with Both Respiratory and Extrarespiratory Involvement. The Journal of Infectious Diseases 2003, 187(4):695-699.
13. Garcia de Viedma D, Marin M, Ruiz MJ, Bouza E. Analysis of clonal composition of Mycobacterium tuberculosis isolates in primary infections in children. J Clin Microbiol 2004, 42(8):3415-3418. 10.1128/JCM.42.8.3415-3418.2004, 497594, 15297476.
14. World Health Organisation: Global tuberculosis control: a short update to the 2009 report. , http://www.who.int/tb/publications/global_report/2009/update/en/index.html
15. Guwatudde D, Nakakeeto M, Jones-Lopez EC, Maganda A, Chiunda A, Mugerwa RD, Ellner JJ, Bukenya G, Whalen CC. Tuberculosis in Household Contacts of Infectious Cases in Kampala, Uganda. Am J Epidemiol 2003, 158(9):887-898. 10.1093/aje/kwg227, 2869090, 14585767.
16. Mudido PM, Guwatudde D, Nakakeeto MK, Bukenya GB, Nsamba D, Johnson JL, Mugerwa RD, Ellner JJ, Whalen CC. The effect of bacille Calmette-Guerin vaccination at birth on tuberculin skin test reactivity in Ugandan children. Int J Tuberc Lung Dis 1999, 3(10):891-895.
17. Whalen CC, Chiunda A, Zalwango S, Nshuti L, Jones-Lopez E, Okwera A, Hirsch C, Peters P, Boom WH, Mugerwa RD. Immune correlates of acute Mycobacterium tuberculosis infection in household contacts in Kampala, Uganda. Am J Trop Med Hyg 2006, 75(1):55-61. 2869089, 16837709.
18. Muhumuza J, Asiimwe BB, Kayes S, Mugyenyi P, Whalen C, Mugerwa RD, Boom H, Eisenach KD, Joloba ML. Introduction of an in-house PCR for routine identification of M. tuberculosis in a low-income country. The International Journal of Tuberculosis and Lung Disease 2006, 10:1262-1267.
19. Supply P, Allix C, Lesjean S, Cardoso-Oelemann M, Rusch-Gerdes S, Willery E, Savine E, de Haas P, van Deutekom H, Roring S, et al. Proposal for Standardization of Optimized Mycobacterial Interspersed Repetitive Unit-Variable-Number Tandem Repeat Typing of Mycobacterium tuberculosis. J Clin Microbiol 2006, 44(12):4498-4510. 10.1128/JCM.01392-06, 1698431, 17005759.
20. Multilocus Variable Number Tandem Repeat Genotyping of Mycobacterium tuberculosis, Technical Guide. , http://www.miru-vntrplus.org/MIRU/index.faces
21. De Cock KM, Soro B, Coulibaly IM, Lucas SB. Tuberculosis and HIV infection in sub-Saharan Africa. JAMA 1992, 268(12):1581-1587. 10.1001/jama.268.12.1581, 1518113.
22. Kox LF, Rhienthong D, Miranda AM, Udomsantisuk N, Ellis K, van Leeuwen J, van Heusden S, Kuijper S, Kolk AH. A more reliable PCR for detection of Mycobacterium tuberculosis in clinical samples. J Clin Microbiol 1994, 32(3):672-678. 263105, 8195377.