Aseptic meningitis caused by Leptospira spp diagnosed by polymerase chain reaction

Memorias do Instituto Oswaldo Cruz

Volumn 105, Issue 8, 2010, Pages 988-992

  Romero, Eliete Caló ^a   Blanco, Roberta Morozetti ^a   Yasuda, Paulo Hideki ^b  

^a INSTITUTO ADOLFO LUTZ   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Aseptic meningitis; CSF; Diagnosis; Leptospira spp; Leptospirosis; PCR

Indexed keywords

LEPTOSPIRA;

EID: 78650805820     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762010000800007     Document Type: Article

References (46)

1. Amato Neto V, de Avila CA, Kawarabayashi M 1982. Leptospira meningitis: cases reported in the city of São Paulo, during an epidemic outbreak of meningococcal disease. Rev Inst Med Trop Sao Paulo 24: 322-325.
2. Arnoni MV, Berezin EN, Sáfadi MA, Almeida FJ, Lopes CR 2007. Streptococcus pyogenes meningitis in children: report of two cases and literature review. Braz J Infect Dis 11: 375-377.
3. Avery RA, Frank G, Eppes SC 2005. Diagnostic utility of Borrelia burgdorferi cerebrospinal fluid polymerase chain reaction in children with Lyme meningitis. Pediatr Infect Dis J 24: 705-708.
4. Bäckman A, Lantz P, Rädström P, Olcén P 1999. Evaluation of an extended diagnostic PCR assay for detection and verification of the common causes of bacterial meningitis in CSF and other biological samples. Mol Cell Probes 13: 49-60.
5. Beeson PB, Hankey DD 1950. "Benign aseptic meningitis" as a manifestation of leptospiral infection. Trans Assoc Am Physicians 63: 130-135.
6. Beeson PB, Hankey DD 1952. Leptospiral meningitis. AMA Arch Intern Med 89: 575-583.
7. Bigham RS Jr 1953. Benign aseptic meningitis due to Leptospira grippotyphosa; second report of clinical infection in the United States. AMA Arch Intern Med 92: 587-590.
8. Corrêa MO, Hyakutake S, Natale V, Tiriba A da C, Martirani I, Galvão PA, Albano A, de Filippi J, Farhat CK, Neto VA 1971. Human leptospirosis due to Leptospira andamana. Rev Inst Med Trop Sao Paulo 13: 137-143.
9. de Almeida SM, Nogueira MB, Raboni SM, Vidal LR 2007. Laboratorial diagnosis of lymphocytic meningitis. Braz J Infect Dis 11: 489-495.
10. de Souza AL, Sztajnbok J, Marques SR, Seguro AC 2006. Leptospirosis- induced meningitis and acute renal failure in a 19-month-old male child. J Med Microbiol 55: 795-797.
11. du Plessis M, Smith AM, Klugman KP 1998. Rapid detection of penicillin- resistant Streptococcus pneumoniae in cerebrospinal fluid by a seminested-PCR strategy. J Clin Microbiol 36: 453-457.
12. Faine S, Adler B, Bolin C, Perolat P 1999. Leptospira and leptospirosis, 2nd ed., MediSci, Melbourne, 272 pp.
13. Faucher JF, Hoen B, Estavoyer JM 2004. The management of leptospirosis. Expert Opin Pharmacother 5: 819-827.
14. Feigin RD, Anderson DC 1975. Human leptospirosis. CRC Crit Rev Clin Lab Sci 5: 413-467.
15. Gollop JH, Pang L, Sasaki DM 1990. Leptospirosis: a possible cause of "aseptic meningitis". Hawaii Med J 49: 162-165.
16. Karande S, Patil S, Kulkarni M, Joshi A, Bharadwaj R 2005. Acute aseptic meningitis as the only presenting feature of leptospirosis. Pediatr Infect Dis J 24: 390-391.
17. Khatami A, Pollard AJ 2010. The epidemiology of meningococcal disease and the impact of vaccines. Expert Rev Vaccines 9: 285-298.
18. Kim KS 2010. Acute bacterial meningitis in infants and children. Lancet Infect Dis 10: 32-42.
19. King SD, Urquhart AE 1975. Laboratory investigations on four cases of leptospiral meningitis in Jamaica. West Indian Med J 24: 196-201.
20. Kitaoka M, Hyakutare S, Mori M 1976. Identification of Leptospira andamana isolated from the spinal fluid of a fatal case of leptospirosis in São Paulo, 1963. J Hyg Epidemiol Microbiol Immunol 20: 437-442.
21. Lammie GA, Hewlett RH, Schoeman JF, Donald PR 2009. Tuberculous cerebrovascular disease: a review. J Infect 59: 156-166.
22. Levett PN 2001. Leptospirosis. Clin Microbiol Rev 14: 296-326.
23. Lin AL, Safdieh JE 2010. The evaluation and management of bacterial meningitis: current practice and emerging developments. Neurologist 16: 143-151.
24. Lorino G, Lilli D, Rivanera D, Guarino P, Angeletti S, Gherardi G, Filadoro F 1999. Polymerase chain reaction, with sequencing, as a diagnostic tool in culture-negative bacterial meningitis. Clin Microbiol Infect 5: 92-96.
25. Margall Coscojuela N, Majó Moreno M, Latorre Otín C, Fontanals Amyerich D, Domínguez García A, Prats Pastor G 2002. Use of universal PCR on cerebrospinal fluid to diagnose bacterial meningitis in culture-negative patients. Eur J Clin Microbiol Infect Dis 21: 67-69.
26. Marí JM, Ruiz MP, Anza DV 2010. Laboratory diagnosis of lymphocytic meningitis. Enferm Infecc Microbiol Clin 28 (Suppl. 1): 56-61.
27. Mathew T, Satishchandra P, Mahadevan A, Nagarathna S, Yasha TC, Chandramukhi A, Subbakrishna DK, Shankar SK 2006. Neuroleptospirosis - revisited: experience from a tertiary care neurological centre from south India. Indian J Med Res 124: 155-162.
28. Mérien F, Amouriaux P, Perolat P, Baranton G, Saint Girons I 1992. Polymerase chain reaction for detection of Leptospira spp in clinical samples. J Clin Microbiol 30: 2219-2224.
29. Merwick A, Kelly S, Galvin R 2008. Meningitis due to leptospiria hardjo-identifying a treatable cause of aseptic lymphocytic meningitis. Ir Med J 101: 91.
30. Mourvillier B, Wolff M 2006. Infectious meningitis and meningoencephalitis in the adult. Rev Prat 56: 1927-1932.
31. MS - Ministério da Saúde 2007. [homepage on the Internet]. [accessed 24 April 2010] Available from: portal.saude.gov.br/portal/arquivos/ pdf/leptos_casos.pdf.
32. Nelsen S, Sealy DP, Schneider EF 1993. The aseptic meningitis syndrome. Am Fam Physician 48: 809-815.
33. Ni H, Knight AI, Cartwright K, Palmer WH, McFadden J 1992. Polymerase chain reaction for diagnosis of meningococcal meningitis. Lancet 340: 1432-1434.
34. Romero EC, Bernardo CC, Yasuda PH 2003. Human leptospirosis: a twenty-nine-year serological study in São Paulo, Brazil. Rev Inst Med Trop Sao Paulo 45: 245-248.
35. Romero EC, Billerbeck AE, Lando VS, Camargo ED, Souza CC, Yasuda PH 1998. Detection of Leptospira DNA in patients with aseptic meningitis by PCR. J Clin Microbiol 36: 1453-1455.
36. Romero EC, Blanco RM, Galloway RL 2009. Application of pulsedfield gel electrophoresis for the discrimination of leptospiral isolates in Brazil. Lett Appl Microbiol 48: 623-627.
37. Romero EC, Yasuda PH 2006. Molecular characterization of Leptospira sp. strains isolated from human subjects in São Paulo, Brazil using a polymerase chain reaction-based assay: a public health tool. Mem Inst Oswaldo Cruz 101: 373-378.
38. Sackett DL, Haynes RB, Guyatt GH, Tugwell P 1991. Clinical epidemiology: a basic science for clinical medicine, 2nd ed., Little Brown and Company, Boston, 441 pp.
39. Sakata EE, Yasuda PH, Romero EC, Silva MV, Lomar AV 1992. The serovars of Leptospira interrogans isolated from cases of human leptospirosis in São Paulo, Brazil. Rev Inst Med Trop Sao Paulo 34: 217-221.
40. Saravolatz LD, Manzor O, VanderVelde N, Pawlak J, Belian B 2003. Broad-range bacterial polymerase chain reaction for early detection of bacterial meningitis. Clin Infect Dis 36: 40-45.
41. Schlech WF 3rd 1992. The epidemiology of bacterial meningitis. Antibiot Chemother 45: 5-17.
42. Silva HR, Tanajura GM, Tavares-Neto J, Gomes MM de L, Linhares AA da C, Vasconcelos PF, Ko AI 2002. Aseptic meningitis syndrome due to enterovirus and Leptospira sp. in children of Salvador, Bahia. Rev Soc Bras Med Trop 35: 159-165.
43. Sperber SJ, Schleupner CJ 1989. Leptospirosis: a forgotten cause of aseptic meningitis and multisystem febrile illness. South Med J 82: 1285-1288.
44. Torre D, Giola M, Martegani R, Zeroli C, Fiori GP, Ferrario G, Bonetta G 1994. Aseptic meningitis caused by Leptospira australis. Eur J Clin Microbiol Infect Dis 13: 496-497.
45. WHO - World Health Organization 1999. Leptospirosis worldwide, 1999. Wkly Epidemiol Rec 74: 237-242.
46. Zambrano Y, Chiarello A, Soca A, Villalobos I, Marrero M, Soler M, Laferte J, Alvarez M 2006. Use of polymerase chain reaction for the diagnosis of central nervous system infections. Invest Clin 47: 337-447.