Screening of platelets for bacterial contamination at the Welsh Blood Service

Transfusion Medicine

Volumn 21, Issue 1, 2011, Pages 25-32

  Pearce, S ^a   Rowe, G P ^a   Field, S P ^a  

^a Welsh Blood Service   (United Kingdom)

Author keywords

Apheresis; Bacterial contamination; Bacterial screening; Platelets; Pooled buffy coat derived

Indexed keywords

APHERESIS; ARTICLE; BACTERIUM CONTAMINATION; BLOOD BANK; BLOOD SAMPLING; COLONY FORMING UNIT; COMPUTER SYSTEM; CONFIDENCE INTERVAL; CONTROLLED STUDY; HUMAN; SCREENING; SENSITIVITY ANALYSIS; THROMBOCYTE; THROMBOCYTE LIFESPAN;

AUTOMATION; BACTERIOLOGICAL TECHNIQUES; BLOOD BANKS; BLOOD BUFFY COAT; BLOOD COMPONENT REMOVAL; BLOOD PLATELETS; BLOOD TRANSFUSION; DISEASE NOTIFICATION; DISEASE TRANSMISSION, INFECTIOUS; GREAT BRITAIN; HUMANS;

EID: 78650800995     PISSN: 09587578     EISSN: 13653148     Source Type: Journal    
DOI: 10.1111/j.1365-3148.2010.01037.x     Document Type: Article

References (26)

1. Benjamin, R.J. & Wagner, S.J. (2007) The residual risk of sepsis: modelling the effect of concentration on bacterial detection in two-bottle culture systems and an estimation of false negative culture rates. Transfusion, 47, 1381-1389.
2. Blajchman, M.A., Beckers, E.A.M., Dickmeiss, E., Lin, L., Moore, G. & Muylle, L. (2005) Bacterial detection of platelets: current problems and possible resolutions. Transfusion Medicine Reviews, 19, 259-272.
3. Blajchman, M.A., Sarwal, S. & Loeb, M.A. (2001) Second example of a transfusion-associated septic reaction associated with Clostridium perfringens [Letters to the editor]. Transfusion, 41, 227.
4. Brecher, M.E. & Hay, S.N. (2007) Investigation of an isolate of Staphylococcus lugdunensis implicated in a platelet fatality: a possible advantage of the use of an anaerobic bottle. Transfusion, 47, 1390-1394.
5. Brecher, M.E., Holland, P.V., Pineda, A.A., Tegtmeier, G.E. & Yomtovian, R. (2000) Growth of bacteria in inoculated platelets: implications for bacteria detection and the extension of platelet storage. Transfusion, 40, 1308-1312.
6. Council of Europe. (2008) Guide to the Preparation Use and Quality Assurance of Blood Components (14th edn). Council of Europe Publishing, Strasbourg. ISBN 978-92-871-6330-1.
7. Dumont, L.J., Kleinman, S., Murphy, J.R., Lippincott, R., Schuyler, R., Houghton, J. & Metzel, P. (2010) Screening of single-donor apheresis platelets for bacterial contamination: the PASSPORT study results. Transfusion, 50, 589-599.
8. Eder, A.F., Kennedy, J.M., Dy, B.A. et al. (2009) Limiting and detecting bacterial contamination of apheresis platelets: inlet-line diversion and increased culture volume improve component safety. Transfusion, 49, 1554-1563
9. Fournier-Wirth, C., Deschaseaux, M., Defer, C. et al. (2006) Evaluation of the enhanced bacterial detection system for screening of contaminated platelets. Transfusion, 46, 220-224.
10. Jacobs, M.R., Bajaksouzian, S., Windau, A., Palavecino, E.L. & Yomtovian, R. (2005) Evaluation of the Scansystem method for detection of bacterially contaminated platelets. Transfusion, 45, 265-269.
11. Jakab, E., Zbinden, R., Gubler, J., Ruef, C., von Graeventiz, A. & Krause, M. (1997) Severe infections caused by Propionibacterium acnes: an underestimated pathogen in late postoperative infections. Yale Journal of Biology and Medicine, 69, 477-482.
12. Kerhoff, J.L.H., van Putten, W.L.J., Novotny, V.M.J. et al. (2010) Clinical effectiveness of leucoreduced pooled donor platelet concentrates, stored in plasma or additive solution with and without pathogen reduction. British Journal of Haematology, 150, 209-217.
13. Kuehnert, M.J., Roth, V.R., Haley, R. et al. (2001) Transfusion-transmitted bacterial infection in the United States, 1998 through 2000. Transfusion, 41, 1493-1499.
14. McDonald, C.P., Hartley, S., Orchard, K., Hughes, G., Brett, M.M., Hewitt, P.E. & Barabara, J.A. (1998) Fatal Clostridium perfringens sepsis from a pooled platelet transfusion. Transfusion Medicine, 8, 19-22.
15. McDonald, C.P., Roy, A., Lowe, P., Robbins, S., Hartley, S. & Barbara, J.A.J. (2001) Evaluation of the BacT/ALERT automated blood culture system for detecting bacteria and measuring their growth kinetics in leucodepleted and non-leucodepleted platelet concentrates. Vox Sanguinis, 81, 154-160.
16. McDonald, C.P., Roy, A., Mahajan, P., Smith, R., Charlett, A. & Barabara, J.A.J. (2004) Relative values of the interventions of diversion and improved donor-arm disinfection to reduce the bacterial risk from blood transfusion. Vox Sanguinis, 86, 178-182.
17. Murphy, W.G., Foley, M., Doherty, C., Tierney, A., Kinsella, A., Salami, A., Cadden, E. & Coakley, P. (2008) Screening platelet concentrates for bacterial contamination: low numbers of bacteria and slow growth in contaminated units mandate an alternative approach to product safety. Vox Sanguinis, 95, 13-19.
18. Perez, P., Salmi, L.R., Follea, G., Schmit, J., de Barbeyrac, B., Sudre, P. & Salamon, R. (2001) Determinants of transfusion-associated bacterial contamination: results of the French BACTHEM Case-Control Study. Transfusion, 41, 862-872.
19. Reimer, L.G., Wilson, M.L. & Weinstein, M.P. (1997) Update on detection of bacteraemia and fungemia. Clinical Microbiology Reviews, 10, 444-465.
20. Schmidt, M., Karakassopoulos, A., Burkhart, J. et al. (2007) Comparison of three bacterial detection methods under routine conditions. Vox Sanguinis, 92, 15-21.
21. Störmer, M., Cassens, U., Kleesiek, K. & Dreier, J. (2007) Detection of bacteria in platelet concentrates prepared from spiked single donations using cultural and molecular genetic methods. Transfusion Medicine, 17, 61-70.
22. Störmer, M., Kleesiek, K. & Dreier, J. (2008) Propionibacterium acnes lacks the capability to proliferate in platelet concentrates. Vox Sanguinis, 94, 193-201.
23. Stramer, S. (2007) Current risks of transfusion-transmitted agents. Archives of Pathology & Laboratory Medicine, 131, 702-707.
24. Taylor, C. (Ed), Cohen, H., Mold, D. et al., on behalf of the Serious Hazards of Transfusion (SHOT) Steering Group. The 2008 Annual SHOT Report (2009).
25. Wagner, S.J. & Eder, A.F. (2007) A model to predict the improvement of automated blood culture bacterial detection by doubling platelet sample volume. Transfusion, 47, 430-433.
26. Wood, E. (2010) Blood safety: bacterial screening of blood products. ISBT Science Series, 5, 46-51.