Clinical effectiveness of leucoreduced, pooled donor platelet concentrates, stored in plasma or additive solution with and without pathogen reduction

British Journal of Haematology

Volumn 150, Issue 2, 2010, Pages 209-217

  Kerkhoffs, Jean Louis H ^a,b   Van Putten, Wim L J ^c   Novotny, Viera M J ^d   Te Boekhorst, Peter A W ^c   Schipperus, Martin R ^b   Zwaginga, Jaap Jan ^e   Van Pampus, Lizzy C M ^d   De Greef, Georgine E ^c   Luten, Marleen ^c   Huijgens, Peter C ^f   Brand, Anneke ^a,e   Van Rhenen, Dick J ^a  

^a Sanquin Blood Bank   (Netherlands)

^b HAGA HOSPITAL   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^f VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

amotosalen UVA pathogen reduction; buffy coat; efficacy; platelet

Indexed keywords

AMOTOSALEN; THROMBOCYTE CONCENTRATE;

ADULT; ARTICLE; BLEEDING; BLOOD BANK; BLOOD DONOR; BLOOD STORAGE; BLOOD TRANSFUSION REACTION; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ERYTHROCYTE TRANSFUSION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE PRESERVATION; THROMBOCYTE TRANSFUSION; ULTRAVIOLET A RADIATION;

ADULT; AGED; BACTERIAL INFECTIONS; BLOOD PLATELETS; BLOOD PRESERVATION; FEMALE; HEMORRHAGE; HUMANS; LEUKOCYTE REDUCTION PROCEDURES; MALE; MIDDLE AGED; PLASMA; PLATELET TRANSFUSION; PSORALENS; THROMBOCYTOPENIA; TREATMENT OUTCOME; ULTRAVIOLET RAYS; VIRUS DISEASES;

EID: 77954322802     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08227.x     Document Type: Article

References (36)

1. Apelseth, T.O., Bruserud, O., Wentzel-Larsen, T., Bakken, A.M., Bjorsvik, S. Hervig, T. (2007) In vitro evaluation of metabolic changes and residual platelet responsiveness in photochemical treated and gamma-irradiated single-donor platelet concentrates during long-term storage. Transfusion, 47, 653 665.
2. Blajchman, M.A., Beckers, E.A., Dickmeiss, E., Lin, L., Moore, G. Muylle, L. (2005) Bacterial detection of platelets: current problems and possible resolutions. Transfusion Medicine Reviews, 19, 259 272.
3. Council of Europe expert committee in blood transfusion study group on pathogen inactivation of labile blood products 2001) pathogen inactivation of labile blood products. Transfusion Medicine, 11, 149 175.
4. Davis, K.B., Slichter, S.J. Corash, L. (1999) Corrected count increment and percent platelet recovery as measures of posttransfusion platelet response: problems and a solution. Transfusion, 39, 586 592.
5. Dodd, R.Y., Notari, E.P. Stramer, S.L. (2002) Current prevalence and incidence of infectious disease markers and estimated window-period risk in the American Red Cross blood donor population. Transfusion, 42, 975 979.
6. Goodnough, L.T., Brecher, M.E., Kanter, M.H. AuBuchon, J.P. (1999) Transfusion medicine: blood transfusion. New England Journal of Medicine, 340, 438 447.
7. Grass, J.A., Wafa, T., Reames, A., Wages, D., Corash, L., Ferrara, J.L. Lin, L. (1999) Prevention of Transfusion-Associated Graft-versus-Host Disease by photochemical treatment. Blood, 93, 3140 3147.
8. Janetzko, K., Lin, L., Eichler, H., Mayaudon, V., Flament, J. Kluter, H. (2004) Implementation of the INTERCEPT Blood System for platelets into routine blood bank manufacturing procedures: evaluation of aphaeresis platelets. Vox Sanguinis, 86, 239 245.
9. Janetzko, K., Cazenave, J.P., Klüter, H., Kientz, D., Michel, M., Beris, P., Lioure, B., Hastka, J., Marblie, S., Mayaudon, V., Lin, L., Lin, J.S., Conlan, M.G. Flament, J. (2005) Therapeutic efficacy and safety of photochemically treated aphaeresis platelets processed with an optimized integrated set. Transfusion, 45, 1443 1452.
10. Jansen, G.A., van Vliet, H.H., Vermeij, H., Beckers, E.A., Leebeek, F.W., Sonneveld, P. van Rhenen, D.J. (2004) Functional characteristics of photochemically treated platelets. Transfusion, 44, 313 319.
11. Kerkhoffs, J.L., Eikenboom, J.C., Schipperus, M.S., van Wordragen-Vlaswinkel, R.J., Brand, R., Harvey, M.S., de Vries, R.R., Barge, R., van Rhenen, D.J. Brand, A. (2006) A multicenter randomized Study of the efficacy of transfusions with platelet stored in platelet additive solution II versus plasma. Blood, 108, 3210 3215.
12. Keuren, J.F., Cauwenberghs, S., Heeremans, J., de Kort, W., Heemskerk, J.W. Curvers, J. (2006) Platelet ADP response deteriorates in synthetic storage media. Transfusion, 46, 204 212.
13. Kuehnert, M., Roth, V. Haley, N. (2001) Transfusion-transmitted bacterial infection in the United States, 1998 - 2000. Transfusion, 41, 1493 1499.
14. Lee, C.K., Ho, P.L., Lee, K.Y., Cheng, W.W., Chan, N.K., Tsoi, W.C. Lin, C.K. (2003) Estimation of bacterial risk in extending the shelf life of PLT concentrates from 5 to 7 days. Transfusion, 43, 1047 1052.
15. Lin, L. (2001) Inactivation of cytomegalovirus in platelet concentrates using Helinx technology. Seminars in haematology, 38, 27 33. (Pubitemid 33096556)
16. Lin, L., Dikeman, R., Molini, B., Lukehart, S.A., Lane, R., Dupuis, K., Metzel, P. Corash, L. (2004) Photochemical treatment of platelet concentrates with amotosalen and long-wavelength ultraviolet light inactivates a broad spectrum of pathogenic bacteria. Transfusion, 44, 1496 1504.
17. Lin, L., Hanson, C.V., Alter, H.J., Jauvin, V., Bernard, K.A., Murthy, K.K., Metzel, P. Corash, L. (2005) Inactivation of viruses in platelet concentrates by photochemical treatment with amotosalen and long-wavelenght ultraviolet light. Transfusion, 45, 580 590.
18. Lozano, M., Galan, A., Mazzara, R., Corash, L. Escolar, G. (2007) Leukoreduced buffy-coat derived platelet concentrates photochemically treated with amotosalen HCl and ultraviolet A light stored up 7 days: assessment of hemostatic function under flow conditions. Transfusion, 47, 666 671.
19. McCullough, J., Vesole, D.H., Benjamin, R.J., Slichter, S.J., Pineda, A., Snyder, E., Stadtmauer, E.A., Lopez-Plaza, I., Coutre, S., Strauss, R.G., Goodnough, L.T., Fridey, J.L., Raife, T., Cable, R., Murphy, S., Howard, F. IV., Davis, K., Lin, J.S., Metzel, P., Corash, L., Koutsoukos, A., Lin, L., Buchholz, D.H. Conlan, M.G. (2004) Therapeutic efficacy and safety of platelets treated with a photochemical process for pathogen inactivation: the SPRINT Trial. Blood, 104, 1534 1541.
20. van der Meer, P.F., Kerkhoffs, J.L., Curvers, J., Scharenberg, J., de Korte, D., Brand, A. de Wildt-Eggen, J. (2009) In vitro comparison of platelet storage in plasma and in four platelet additive solutions, and the effect of pathogen reduction: a proposal for an in vitro rating system. Vox Sanguinis,.
21. Murphy, S., Snyder, E., Cable, R., Slichter, S.J., Strauss, R.G., McCullough, J., Lin, J.S., Corash, L. Conlan, M.G. (2006) Platelet dose consistency and its effect on the number of platelet transfusions for support of thrombocytopenia: an analysis of the SPRINT trial of platelets photochemically treated with amotosalen HCl and ultraviolet A light. Transfusion, 46, 24 33.
22. Osselaer, J.C., Messe, N., Hervig, T., Bueno, J., Castro, E., Espinosa, A., Accorsi, P., Junge, K., Jacquet, M., Flament, J. Corash, L. (2008a) A prospective observational cohort safety study of 5106 platelet transfusions with components prepared with photochemical pathogen inactivation treatment. Transfusion, 48, 1061 1071.
23. Osselaer, J.C., Cazenave, J.P., Lambermont, M., Garraud, O., Hidajat, M., Barbolla, L., Tardivel, R., Defoin, L., Waller, C., Mendel, I., Raidot, J.P., Kandel, G., De Meuter, R., Fabrigli, P., Dehenau, D., Arroyo, J.L., Padrón, F., Gouezec, H., Corral, M., Jacquet, M., Sundin, D., Lin, L. Corash, L. (2008b) An active haemovigilance programme characterizing the safety profile of 7437 platelet transfusions prepared with amotosalen photochemical treatment. Vox Sanguinis, 94, 315 323.
24. Osselaer, J.C., Doyen, C., Defoin, L., Debry, C., Goffaux, M., Messe, N., Van Hooydonk, M., Bosly, A., Lin, J.S., Lin, L. Corash, L. (2009) Universal adoption of pathogen inactivation of platelet components: impact on platelet and red blood cell component use. Transfusion, 49, 1412 1422.
25. Picker, S.M., Speer, R. Gathof, B.S. (2004) Functional characteristics of buff-coat PLTs photochemically treated with amotosalen-HCl for pathogen inactivation. Transfusion, 44, 320 329.
26. Pineda, A., McCullough, J., Benjamin, R.J., Cable, R., Strauss, R.G., Burgstaler, E., Porter, S., Lin, L., Metzel, P. Conlan, M.G. (2006) Pathogen inactivation of platelets with a photochemical treatment with amotosalen HCl and ultraviolet light: process used in the SPRINT trial. Transfusion, 46, 562 571.
27. van Rhenen, D., Gulliksson, H., Cazenave, J.P., Pamphilon, D., Ljungman, P., Klüter, H., Vermeij, H., Kappers-Klunne, M., de Greef, G., Laforet, M., Lioure, B., Davis, K., Marblie, S., Mayaudon, V., Flament, J., Conlan, M., Lin, L., Metzel, P., Buchholz, D. Corash, L. (2003) Transfusion of pooled buffy coat platelet components prepared with photochemical pathogen inactivation treatment: the euro SPRITE trial. Blood, 101, 2426 2433.
28. Schrezenmeier, H., Walther-Wenke, G., Müller, T.H., Weinauer, F., Younis, A., Holland-Letz, T., Geis, G., Asmus, J., Bauerfeind, U., Burkhart, J., Deitenbeck, R., Förstemann, E., Gebauer, W., Höchsmann, B., Karakassopoulos, A., Liebscher, U.M., Sänger, W., Schmidt, M., Schunter, F., Sireis, W. Seifried, E. (2007) Bacterial contamination of platelet concentrates: results of a prospective multicenter study comparing pooled whole blood-derived platelets and apheresis platelets. Transfusion, 47, 644 652.
29. Simonsen, A.C., Johansson, P.I., Conlan, M.G., Jacquet, M., Lin, J.S., Junge, K., Lin, L., Sørensen, H., Borregaard, N. Flament, J. (2006) Transfusion of 7-day old amotosalen photochemically treated buffy-coat platelets to patients with thrombocytopenia: a pilot study. Transfusion, 46, 424 433.
30. Slichter, S.J. (2007) Platelet transfusion therapy. Hematology/Oncology Clinics of North America, 21, 697 729.
31. Slichter, S.J., Raife, T.J., Davis, K., Rheinschmidt, M., Buchholz, D.H., Corash, L. Conlan, M.G. (2006) Platelets photochemically treated with amotosalen HCl and ultraviolet A light correct prolonged bleeding times in patients with thrombocytopenia. Transfusion, 46, 731 740.
32. Slichter, S.J., Kaufman, R.M., Assmann, S.F., McCullough, J., Triulzi, D.J., Strauss, R.G., Gernsheimer, T.B., Ness, P.M., Brecher, M.E., Josephson, C.D., Konkle, B.A., Woodson, R.D., Ortel, T.L., Hillyer, C.D., Skerret, D.L., McCrae, K.R., Sloan, S.R., Uhl, L., George, J.N., Aquino, V.M., Manno, C.S., McFarland, J.G., Hess, J.R., Leissinger, C. Granger, S. (2010) Dose of Prophylactic Platelet Transfusions and Prevention of Hemorrhage. New England Journal of Medicine, 362, 600 613.
33. 111Indium-radiolabeled platelets treated with pathogen inactivation with amotosalen HCl (S-59) and ultraviolet light. Transfusion, 44, 1732 1740.
34. Snyder, E., McCullough, J., Slichter, S.J., Strauss, R.G., Lopez-Plaza, I., Lin, J.S., Corash, L. Conlan, M.G. (2005) Clinical safety of platelets photochemical treated with amotosalen HCl and ultraviolet A light for pathogen inactivation: the SPRINT trial. Transfusion, 45, 1864 1875.
35. Stroncek, D.F. Rebulla, P. (2007) Platelet transfusions. Lancet, 370, 427 438.
36. Van Rhenen, D.J., Vermeij, J., Mayaudon, V., Hind, C., Lin, L. Corash, L. (2000) Functional characteristics of S-59 photochemically treated platelet concentrates derived from buffy coats. Vox Sanguinis, 79, 206 214.