Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Dillon, Patrick F ^a   Root Bernstein, Robert ^a   Edward Robinson, N ^a   Abraham, William M ^b   Berney, Catherine ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ADRENALIN; ASCORBIC ACID; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CARBACHOL; DEHYDROASCORBIC ACID; ISOPRENALINE; SALBUTAMOL; BETA ADRENERGIC RECEPTOR; HISTAMINE;

AIRWAY OBSTRUCTION; AIRWAY RESISTANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BINDING AFFINITY; BRONCHOSPASM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; DRUG RECEPTOR BINDING; GUINEA PIG; HORSE; IN VITRO STUDY; IN VIVO STUDY; MUSCLE RELAXATION; NONHUMAN; SHEEP; SWINE; TACHYPHYLAXIS; TRACHEA MUSCLE; ULTRAVIOLET SPECTROSCOPY; ANIMAL; CHEMISTRY; METABOLISM; METHODOLOGY; ULTRAVIOLET SPECTROPHOTOMETRY;

CAVIA; EQUIDAE; OVIS ARIES; SUIDAE;

ADRENERGIC BETA-AGONISTS; ALBUTEROL; ANIMALS; ASCORBIC ACID; BRONCHOCONSTRICTION; CARBACHOL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPINEPHRINE; GUINEA PIGS; HISTAMINE; HORSES; RECEPTORS, ADRENERGIC, BETA; SHEEP; SPECTROPHOTOMETRY, ULTRAVIOLET; SWINE;

EID: 78650790075     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015130     Document Type: Article

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