Investigation of the Neural Target Level of Hyperthyroidism in Premature Ejaculation in a Rat Model of Pharmacologically Induced Ejaculation

Journal of Sexual Medicine

Volumn 8, Issue 1, 2011, Pages 90-96

  Cahangirov, Asif ^a   Cihan, Ahmet ^a   Murat, Nergis ^a   Demir, Omer ^a   Aslan, Guven ^a   Gidener, Sedef ^a   Esen, Ahmet Adil ^a  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

Ejaculation; Ejaculatory physiology; Hyperthyroidism; Neural pathway; Thyroid

Indexed keywords

CHLORAMPHETAMINE; LEVOTHYROXINE; THYROTROPIN; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER PRESSURE; CATHETERIZATION; CONTROLLED STUDY; EJACULATION; ELECTROMYOGRAPHY; HYPERTHYROIDISM; MALE; NONHUMAN; PREMATURE EJACULATION; PRIORITY JOURNAL; RAT; SEMINAL VESICLE; SPINE SURGERY; THYROTROPIN BLOOD LEVEL;

EID: 78650761212     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2010.02042.x     Document Type: Article

References (22)

1. Waldinger MD. Premature ejaculation: State of the art. Urol Clin North Am 2007;34:591-9.
2. Corona G, Petrone L, Mannucci E, Jannini EA, Mansani R, Magini A, Giommi R, Forti G, Maggi M. Psycho-biological correlates of rapid ejaculation in patients attending an andrologic unit for sexual dysfunctions. Eur Urol 2004;46:615-22.
3. Carani C, Isidori AM, Granata A, Carosa E, Maggi M, Lenzi A, Jannini EA. Multicenter study on the prevalence of sexual symptoms in male hypo- and hyperthyroid patients. J Clin Endocrinol Metab 2005;90:6472-9.
4. Cihan A, Demir O, Demir T, Aslan G, Comlekci A, Esen A. The relationship between premature ejaculation and hyperthyroidism. J Urol 2009;181:1273-80.
5. Cihan A, Murat N, Demir O, Aslan G, Demir T, Gidener S, Esen AA. An experimental approach to interrelation between hyperthyroidism and premature ejaculation. J Urol 2009;181:907-12.
6. Coolen LM, Allard J, Truitt WA, Mc Kenna KE. Central regulation of ejaculation. Physiol Behav 2004;83:203-15.
7. Rowland D, McMahon CG, Abdo C, Chen J, Jannini E, Waldinger MD, Ahn TY. Disorders of orgasm and ejaculation in men. J Sex Med 2010;7:1668-86.
8. Truit WA, Coolen LM. Identification of a potential ejaculation generator in the spinal cord. Science 2002;297:1561-9.
9. Xu C, Giuliano F, Yaici ED, Conrath M, Trassard O, Benoit G, Vergé D. Identification of the lumbar spinal interneurons controlling both prostate and bulbospongiosus muscle simultaneous with two strains of recombinants pseudorabies virus in male rat. Neuroscience 2006;138:561-73.
10. Xu C, Yaici ED, Conrath M, Blanchard P, Leclerc P, Benoît G, Vergé D, Giuliano F. Galanin and neurokinin-1 immunoreactive spinal neurons controlling the prostate and the bulbospongiosus muscle identified by transsynaptic labeling in the rat. Neuroscience 2005;134:1325-41.
11. Carageorgiou H, Pantos C, Zarros A, Mourouzis I, Varonos D, Cokkinos D, Tsakiris S. Changes in antioxidant status, protein concentration, acetylcholinesterase, (Na+, K+)-, and Mg2+ -ATPase activities in the brain of hyper- and hypothyroid adult rats. Metab Brain Dis 2005;20:129-39.
12. Chen HJ. Age and sex difference in serum and pituitary thyrotropin concentrations in the rat: Influence by pituitary adenoma. Exp Gerontol 1984;19:1-6.
13. Clément P, Kia HK, Droupy S, Bernabe J, Alexandre L, Denys P, Giuliano F. Role of peripheral innervation in p-chloroamphetamine-induced ejaculation in anesthetized rats. J Androl 2006;27:381-9.
14. Yonezawa A, Watanabe C, Ando R, Furuta S, Sakurada S, Yoshimura H, Iwanaga T, Kimura Y. Characterization of p-chloroamphetamine-induced penile erection and ejaculation in anesthetized rats. Life Sci 2000;67:3031-9.
15. Humphries CR, Paxinos G, O'Brien M. Mechanisms of PCA-induced hypothermia, ejaculation, salivation and irritability in rats. Pharmacol Biochem Behav 1981;15:197-200.
16. Allard J, Truitt WA, McKenna KE, Coolen LM. Spinal cord control of ejaculation. World J Urol 2005;23:119-26.
17. Xin ZC, Chung WS, Choi YD, Seong DH, Choi YJ, Choi HK. Penile sensitivity in patients with primary premature ejaculation. J Urol 1996;156:979-81.
18. Waldinger MD. The neurobiological approach to premature ejaculation. J Urol 2002;168:2359-67.
19. Alkemade A. Central and peripheral effects of thyroid hormone signalling in the control of energy metabolism. J Neuroendocrinol 2010;22:56-63.
20. la Fleur SE, Kalsbeek A, Wortel J, Buijs RM. Polysynaptic neural pathways between the hypothalamus, including the suprachiasmatic nucleus, and the liver. Brain Res 2000;871:50-6.
21. Kreier F, Fliers E, Voshol PJ, Van Eden CG, Havekes LM, Kalsbeek A, Van Heijningen CL, Sluiter AA, Mettenleiter TC, Romijn JA, Sauerwein HP, Buijs RM. Selective parasympathetic innervation of subcutaneous and intra-abdominal fat-Functional implications. J Clin Invest 2002;110:1243-50.
22. Carosa E, Di Sante S, Rossi S, Castri A, D'Adamo F, Gravina GL, Ronchi P, Kostrouch Z, Dolci S, Lenzi A, Jannini EA. Ontogenetic profile of the expression of thyroid hormone receptors in rat and human corpora cavernosa of the penis. J Sex Med 2010;7:1381-90.