Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse model

Virology

Volumn 410, Issue 1, 2011, Pages 216-227

  Jupille, Henri J ^a   Oko, Lauren ^a   Stoermer, Kristina A ^a   Heise, Mark T ^b,c   Mahalingam, Suresh ^d   Gunn, Bronwyn M ^b,c   Morrison, Thomas E ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d UNIVERSITY OF CANBERRA   (Australia)

Author keywords

Alphavirus; Inflammation; Pathogenesis; Rheumatic disease; Virulence

Indexed keywords

NONSTRUCTURAL PROTEIN 1; PROTEIN PE2; UNCLASSIFIED DRUG; VIRUS PROTEIN;

3' UNTRANSLATED REGION; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANKLE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHIMERA; CONTROLLED STUDY; DISEASE MODEL; GENE DELETION; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MUSCULOSKELETAL SYSTEM INFLAMMATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; ROSS RIVER ALPHA VIRUS; SERUM; VIRUS ATTENUATION; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

ALPHAVIRUS INFECTIONS; ANIMALS; BASE SEQUENCE; CRICETINAE; GENE EXPRESSION REGULATION, VIRAL; INFLAMMATION; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; MUSCULOSKELETAL DISEASES; MUTATION; REASSORTANT VIRUSES; RNA, VIRAL; ROSS RIVER VIRUS; VIRAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

ALPHAVIRUS; MUS; ROSS RIVER VIRUS;

EID: 78650754744     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2010.11.012     Document Type: Article

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