Genotypic shift of porcine circovirus type 2 from PCV-2a to PCV-2b in Spain from 1985 to 2008

Veterinary Journal

Volumn 187, Issue 3, 2011, Pages 363-368

  Cortey, M ^a   Pileri, E ^a   Sibila, M ^a   Pujols, J ^a   Balasch, M ^b   Plana, J ^b   Segales J ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b Fort Dodge Veterinaria   (Spain)

Author keywords

Genetic shift; Pigs; Porcine circovirus type 2; Post weaning multisystemic wasting syndrome; Spain

Indexed keywords

ARTICLE; CIRCOVIRUS; CONTROLLED STUDY; EPIZOOTIOLOGY; GENETIC ANALYSIS; GENOTYPIC SHIFT; LONGITUDINAL STUDY; MOLECULAR PHYLOGENY; NONHUMAN; NUCLEOTIDE SEQUENCE; PIG FARMING; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PORCINE CIRCOVIRUS TYPE 2; PORCINE CIRCOVIRUS TYPE 2A; PORCINE CIRCOVIRUS TYPE 2B; POSTWEANING MULTISYSTEMIC WASTING SYNDROME; RETROSPECTIVE STUDY; SEQUENCE ANALYSIS; SPAIN;

ANIMALS; CIRCOVIRUS; DISEASE OUTBREAKS; FEMALE; GENOTYPE; LONGITUDINAL STUDIES; MALE; PHYLOGENY; POLYMERASE CHAIN REACTION; PORCINE POSTWEANING MULTISYSTEMIC WASTING SYNDROME; RETROSPECTIVE STUDIES; SPAIN; SWINE;

PORCINE CIRCOVIRUS 2; SUIDAE;

EID: 78650745388     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2009.12.023     Document Type: Article

References (50)

1. Allan G.M., McNeilly F., Meehan B.M., Kennedy S., Mackie D.P., Ellis J.A., Clark E.G., Espuna E., Saubi N., Riera P., Bøtner A., Charreyre C.E. Isolation and characterisation of circoviruses from pigs with wasting syndromes in Spain, Denmark and Northern Ireland. Veterinary Microbiology 1999, 66:115-123.
2. Allan G., Krakowa S., Ellis J. PCV2: ticking the time bomb. Pig Progress 2002, 18:13-15.
3. Allan G.M., McNeilly F., McMenamy M., McNair I., Krakowka S.G., Timmusk S., Walls D., Donnelly M., Minahin D., Ellis J., Wallgren P., Fossum C. Temporal distribution of porcine circovirus 2 genogroups recovered from postweaning multisystemic wasting syndrome affected and nonaffected farms in Ireland and Northern Ireland. Journal of Veterinary Diagnostic Investigation 2007, 19:668-673.
4. Anderson M.J. PCO: a FORTRAN computer program for principal coordinate analysis 2003, Department of Statistics, University of Auckland, New Zealand.
5. Armstrong, D., Bishop, S., 2004. Does genetics or litter effect influence mortality in PMWS. In: Proceedings of the International Pig Veterinary Society Congress, Copenhagen, Denmark, p. 809.
6. Chae C. A review of porcine circovirus 2-associated syndromes and diseases. The Veterinary Journal 2005, 169:326-336.
7. Cheung A.K., Lager K.M., Kohutyuk O.I., Vincent A.L., Henry S.C., Baker R.B., Rowland R.R., Dunham A.G. Detection of two porcine circovirus type 2 genotypic groups in United States swine herds. Archives of Virology 2007, 152:1035-1044.
8. de Boisseson C., Beven V., Bigarre L., Thiery R., Rose N., Eveno E., Madec F., Jestin A. Molecular characterization of porcine circovirus type 2 isolates from post-weaning multisystemic wasting syndrome-affected and non-affected pigs. Journal of General Virology 2004, 85:293-304.
9. Dupont K., Nielsen E.O., Baekbo P., Larsen L.E. Genomic analysis of PCV2 isolates from Danish archives and a current PMWS case-control study supports a shift in genotypes with time. Veterinary Microbiology 2008, 128:56-64.
10. Felsenstein J. PHYLIP - phylogeny inference package (version 3.2). Cladistics 1989, 5:164-166.
11. Finlaison D., Kirkland P., Luong R., Ross A. Survey of porcine circovirus 2 and postweaning multisystemic wasting syndrome in New South Wales piggeries. Australian Veterinary Journal 2007, 85:304-331.
12. Fort M., Sibila M., Allepuz A., Mateu E., Roerink F., Segalés J. Porcine circovirus type 2 (PCV2) vaccination of conventional pigs prevents viremia against PCV2 isolates of different genotypes and geographic origins. Vaccine 2008, 26:1063-1071.
13. Gagnon C.A., Tremblay D., Tijssen P., Venne M.H., Houde A., Elahi S.M. The emergence of porcine circovirus 2b genotype (PCV2b) in swine in Canada. Canadian Veterinary Journal 2007, 48:811-819.
14. Grau-Roma L., Crisci E., Sibila M., Lopez-Soria S., Nofrarias M., Cortey M., Fraile L., Olvera A., Segalés J. A proposal on porcine circovirus type 2 (PCV2) genotype definition and their relation with postweaning multisystemic wasting syndrome (PMWS) occurrence. Veterinary Microbiology 2008, 128:23-35.
15. Grierson S.S., King D.P., Wellenberg G.J., Banks M. Genome sequence analysis of 10 Dutch porcine circovirus type 2 (PCV2) isolates from a PMWS case-control study. Research in Veterinary Science 2004, 77:265-268.
16. Hall T.A. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symposium Series 1999, 41:95-98.
17. Hamel A.L., Lin L.L., Nayar G.P. Nucleotide sequence of porcine circovirus associated with postweaning multisystemic wasting syndrome in pigs. Journal of Virology 1998, 72:5262-5267.
18. Harding J., Clark E. Recognizing and diagnosing postweaning multisystemic wasting syndrome (PMWS). Journal of Swine Health and Production 1998, 5:201-203.
19. Horlen K.P., Schneider P., Anderson J. A cluster of farms experiencing severe porcine circovirus associated disease: clinical features and association with the PCV2b genotype. Journal of Swine Health and Production 2007, 15:270-278.
20. Lager K.M., Gauger P.C., Vincent A.L., Opriessnig T., Kehrli M.E., Cheung A.K. Mortality in pigs given porcine circovirus type 2 subgroup 1 and 2 viruses derived from DNA clones. Veterinary Record 2007, 161:428-429.
21. Larochelle R., Magar R., D'Allaire S. Genetic characterization and phylogenetic analysis of porcine circovirus type 2 (PCV2) strains from cases presenting various clinical conditions. Virus Research 2002, 90:101-112.
22. Larochelle R., Magar R., D'Allaire S. Comparative serologic and virologic study of commercial swine herds with and without postweaning multisystemic wasting syndrome. Canadian Journal of Veterinary Research 2003, 67:114-120.
23. Lefebvre D.J., Costers S., Van Doorsselaere J., Misinzo G., Delputte P.L., Nauwynck H.J. Antigenic differences among porcine circovirus type 2 strains, as demonstrated by the use of monoclonal antibodies. Journal of General Virology 2008, 89:177-187.
24. Liu J., Chen I., Du Q., Chua H., Kwang J. The ORF3 protein of porcine circovirus type 2 is involved in viral pathogenesis in vivo. Journal of Virology 2006, 80:5065-5073.
25. Mahé D., Blanchard P., Truong C., Arnauld C., Le Cann P., Cariolet R., Madec F., Albina E., Jestin A. Differential recognition of ORF2 protein from type 1 and type 2 porcine circoviruses and identification of immunorelevant epitopes. Journal of General Virology 2000, 81:1815-1824.
26. Mankertz A., Mankertz J., Wolf K., Buhk H.J. Identification of a protein essential for replication of porcine circovirus. Journal of General Virology 1998, 79:381-384.
27. Mankertz A., Domingo M., Folch J.M., LeCann P., Jestin A., Segalés J., Chmielewicz B., Plana-Duran J., Soike D. Characterisation of PCV2 isolates from Spain, Germany and France. Virus Research 2000, 66:65-77.
28. Martins Gomes de Castro A.M., Cortez A., Heinemann M.B., Brandao P.E., Richtzenhain L.J. Genetic diversity of Brazilian strains of porcine circovirus type 2 (PCV2) revealed by analysis of the of cap gene (ORF-2). Archives of Virology 2007, 152:1435-1445.
29. McNeilly F., McNair I., Mackie D.P., Meehan B.M., Kennedy S., Moffett D., Ellis J., Krakowka S., Allan G.M. Production, characterisation and applications of monoclonal antibodies to porcine circovirus 2. Archives of Virology 2001, 146:909-922.
30. Meehan B.M., McNeilly F., McNair I., Walker I., Ellis J.A., Krakowka S., Allan G.M. Isolation and characterization of porcine circovirus 2 from cases of sow abortion and porcine dermatitis and nephropathy syndrome. Archives of Virology 2001, 146:835-842.
31. Nawagitgul P., Morozov I., Bolin S.R., Harms P.A., Sorden S.D., Paul P.S. Open reading frame 2 of porcine circovirus type 2 encodes a major capsid protein. Journal of General Virology 2000, 81:2281-2287.
32. Olvera A., Cortey M., Segalés J. Molecular evolution of porcine circovirus type 2 genomes: phylogeny and clonality. Virology 2007, 357:175-185.
33. Opriessnig T., Patterson A.R., Elsener J., Meng X.J., Halbur P.G. Influence of maternal antibodies on efficacy of porcine circovirus type 2 (PCV2) vaccination to protect pigs from experimental infection with PCV2. Clinical and Vaccine Immunology 2008, 15:397-401.
34. Opriessnig T., Ramamoorthy S., Madson D.M., Patterson A.R., Pal N., Carman S., Meng X.J., Halbur P.G. Differences in virulence among porcine circovirus type 2 isolates are unrelated to cluster type 2a or 2b and prior infection provides heterologous protection. Journal of General Virology 2008, 89:2482-2491.
35. Pogranichniy R.M., Yoon K.J., Harms P.A., Sorden S.D., Daniels M. Case-control study on the association of porcine circovirus type 2 and other swine viral pathogens with postweaning multisystemic wasting syndrome. Journal of Veterinary Diagnostic Investigation 2002, 14:449-456.
36. Quintana J., Balasch M., Segales J., Calsamiglia M., Rodriguez-Arrioja G.M., Plana-Duran J., Domingo M. Experimental inoculation of porcine circoviruses type 1 (PCV1) and type 2 (PCV2) in rabbits and mice. Veterinary Research 2002, 33:229-237.
37. Segalés J., Sitjar M., Domingo M., Dee S., Del Pozo M., Noval R., Sacristan C., De las Heras A., Ferro A., Latimer K.S. First report of post-weaning multisystemic wasting syndrome in pigs in Spain. Veterinary Record 1997, 141:600-601.
38. Segalés J., Calsamiglia M., Domingo M. Post-weaning multisystemic wasting syndrome (PMWS) and porcine circovirus type 2 infection in Spain. Pig Journal 2003, 51:98-107.
39. Segalés J., Allan G.M., Domingo M. Porcine circovirus diseases. Animal Health Research Reviews 2005, 6:119-142.
40. Segalés J., Olvera J., Grau-Roma L., Charreyre C., Nauwynck H., Larsen L., Dupont K., McCullough K., Ellis J., Krakowka S., Mankertz A., Fredholm M., Fossum C., Timmusk S., Stockhofe-Zurwieden N., Beattie V., Armstrong D., Grassland B., Baekbo P., Allan G. PCV2 genotype definition and nomenclature. Veterinary Record 2008, 162:867-868.
41. Shang S.B., Jin Y.L., Jiang X.T., Zhou J.Y., Zhang X., Xing G., He J.L., Yan Y. Fine mapping of antigenic epitopes on capsid proteins of porcine circovirus, and antigenic phenotype of porcine circovirus type 2. Molecular Immunology 2009, 46:327-334.
42. Tamura K., Nei M. Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. Molecular Biology and Evolution 1993, 10:512-526.
43. Tamura K., Dudley J., Nei M., Kumar S. MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Molecular Biology and Evolution 2007, 24:1596-1599.
44. Timmusk, S., Wallgren, P., Belak, K., Berg, M., Fossum, C., 2005. Genetic analysis of PCV2 capsid protein sequences reveals two main groups of Swedish isolates. In: Proceedings of European Society for Veterinary Virology (ESVV). Conference on Animal Circoviruses and Associated Diseases, p. 82.
45. Timmusk S., Wallgren P., Brunborg I.M., Hasslung F., Allan G., Meehan B., McMenamy M., McNeilly F., Fuxler L., Belák K., Põdersoo D., Saar T., Berg M., Fossum C. Phylogenetic analysis of porcine circovirus type 2 (PCV2) pre- and post-epizootic postweaning multisystemic wasting syndrome (PMWS). Virus Genes 2008, 36:509-520.
46. Tomás A., Fernandes L.T., Valero O., Segalés J. A meta-analysis on experimental infections with porcine circovirus type 2 (PCV2). Veterinary Microbiology 2008, 132:260-273.
47. Vigre H., Baekbo P., Jorsal S.E., Bille-Hansen V., Hassing A.G., Enoe C., Botner A. Spatial and temporal patterns of pig herds diagnosed with postweaning multisystemic wasting syndrome (PMWS) during the first two years of its occurrence in Denmark. Veterinary Microbiology 2005, 110:17-26.
48. Wen L., Guo X., Yang H. Genotyping of porcine circovirus type 2 from a variety of clinical conditions in China. Veterinary Microbiology 2005, 110:141-146.
49. Wiederkehr D.D., Sydler T., Buergi E., Haessig M., Zimmermann D., Pospischil A., Brugnera E., Sidler X. A new emerging genotype subgroup within PCV2b dominates the PMWS epizooty in Switzerland. Veterinary Microbiology 2009, 136:27-35.
50. Woodbine K.A., Medley G.F., Slevin J., Kilbride A.L., Novell E.J., Turner M.J., Keeling M.J., Green L.E. Spatiotemporal patterns and risks of herd breakdowns in pigs with postweaning multisystemic wasting syndrome. Veterinary Record 2007, 160:751-762.