Effects of epidermal turnover on the dynamics of percutaneous drug absorption

Mathematical Biosciences

Volumn 229, Issue 1, 2011, Pages 16-21

  Simon, Laurent ^a   Kim, Kwang S ^a   Kanneganti, Kumud ^a  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Effective time constant; Epidermal turnover; Percutaneous absorption

Indexed keywords

EFFECTIVE TIME; EPIDERMAL TURNOVER; FUNDAMENTAL EQUATIONS; LIPOPHILICITY; PENETRATION RATES; PERCUTANEOUS ABSORPTION; PERCUTANEOUS DRUG ABSORPTION; PHYSICOCHEMICAL PROPERTY; RESIDUE THEOREM; SKIN LAYER; STRATUM CORNEUM; SYSTEMIC CIRCULATION; TIME CONSTANTS;

DRUG DELIVERY; EQUILIBRIUM CONSTANTS; LAPLACE TRANSFORMS; RATE CONSTANTS;

ABSORPTION;

ABSORPTION; DRUG; EQUILIBRIUM; LAPLACE TRANSFORM; PHYSICOCHEMICAL PROPERTY;

ARTICLE; DRUG ABSORPTION; DRUG TRANSPORT; EPIDERMIS; EPIDERMIS CELL; LIPOPHILICITY; MATHEMATICAL MODEL; MOLECULAR WEIGHT; PHYSICAL CHEMISTRY; SKIN ABSORPTION; SKIN EXFOLIATION; SKIN SURFACE; STEADY STATE; STRATUM CORNEUM; SYSTEMIC CIRCULATION;

ADMINISTRATION, CUTANEOUS; ALGORITHMS; ANIMALS; COMPUTER SIMULATION; DIFFUSION; EPIDERMIS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; MODELS, BIOLOGICAL; MOLECULAR WEIGHT; PHARMACEUTICAL PREPARATIONS; SKIN ABSORPTION;

EID: 78650741619     PISSN: 00255564     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mbs.2010.10.004     Document Type: Article

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