A novel, biodegradable and reversible polyelectrolyte platform for topical-colonic delivery of pentosan polysulphate

International Journal of Pharmaceutics

Volumn 404, Issue 1-2, 2011, Pages 124-132

  Shah, Hardik K ^a   Conkie, Jim A ^b   Tait, Robert C ^b   Johnson, James R ^a   Wilson, Clive G ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b GLASGOW ROYAL INFIRMARY   (United Kingdom)

Author keywords

Bacterial enzymes; Chitosan; Colonic delivery; Pentosan polysulphate; Poly acrylic acid; Polyelectrolyte complex

Indexed keywords

BACTERIAL ENZYME; BETA GLUCURONIDASE; CHITOSAN; GLUCOSIDASE; PENTOSAN POLYSULFATE; POLYACRYLIC ACID; POLYELECTROLYTE; SALICYLIC ACID;

ARTICLE; CECUM; COLON; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; HYDROGEL; INFRARED SPECTROSCOPY; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTEIN CONTENT; RAT;

ACRYLIC RESINS; ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTICOAGULANTS; BACTERIA; BLOOD COAGULATION; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; COLON; DIGESTION; DRUG CARRIERS; DRUG COMPOUNDING; GASTROINTESTINAL AGENTS; GLUCOSIDASES; GLUCURONIDASE; HYDROGELS; HYDROGEN-ION CONCENTRATION; KINETICS; MALE; PARTIAL THROMBOPLASTIN TIME; PENTOSAN SULFURIC POLYESTER; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TECHNOLOGY, PHARMACEUTICAL;

EID: 78650679913     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.11.012     Document Type: Article

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