Differential efficiency of simvastatin and lipoic acid treatments on Bothrops jararaca envenomation-induced acute kidney injury in mice

Toxicon

Volumn 57, Issue 1, 2011, Pages 148-156

  Barone, Juliana Marton ^a   Alponti, Rafaela Fadoni ^a   Frezzatti, Rodrigo ^a   Zambotti Villela, Leonardo ^a   Silveira, Paulo Flávio ^a  

^a INSTITUTO BUTANTAN   (Brazil)

Author keywords

Acute kidney injury; Comparative toxinology; Lipoic acid; Peptidases; Redox status; Snake envenomation; Statins

Indexed keywords

AMINOPEPTIDASE; CREATININE; SIMVASTATIN; SNAKE VENOM; THIOCTIC ACID; UREA;

ACUTE KIDNEY FAILURE; ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ENVENOMATION; ENZYME ACTIVITY; HEMATOCRIT; HYPEROSMOLALITY; HYPERURICEMIA; KIDNEY CORTEX; KIDNEY FUNCTION; KIDNEY MEDULLA; MALE; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; UREA BLOOD LEVEL;

ACUTE KIDNEY INJURY; AMINOPEPTIDASES; ANIMALS; ANTICHOLESTEREMIC AGENTS; ANTIOXIDANTS; BOTHROPS; CROTALID VENOMS; DISEASE MODELS, ANIMAL; KIDNEY; KIDNEY FUNCTION TESTS; MALE; MICE; OXIDATIVE STRESS; SIMVASTATIN; SNAKE BITES; THIOCTIC ACID; TREATMENT OUTCOME;

BOTHROPS; BOTHROPS JARARACA; MUS;

EID: 78650678653     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2010.11.006     Document Type: Article

References (48)

1. Agarwal R. Effects of statins on renal function. Mayo Clin. Proc. 2007, 82:1381-1390.
2. Ajith T.A., Jose N., Janardhanan K.K. Amelioration of cisplatin induced nephrotoxicity in mice by ethyl acetate extract of a polypore fungus, Phellinus rimosus. J. Exp. Clin. Cancer Res. 2002, 21:213-217.
3. Alegre V.S., Barone J.M., Yamasaki S.C., Zambotti-Villela L., Silveira P.F. Lipoic acid effects on renal function, aminopeptidase activities and oxidative stress in Crotalus durissus terrificus envenomation in mice. Toxicon 2010, 56:402-410.
4. Amaral C.F., Rezende N.A., da Silva O.A., Ribeiro M.M., Magalhães R.A., dos Reis R.J., Carneiro J.G., Castro J.R. Insuficiência renal aguda secundária a acidentes botrópico e crotálico. Análise de 63 casos. Rev. Inst. Med. Trop. São Paulo 1986, 28:220-227.
5. Amudha G., Josephine A., Varalakshmi P. Role of lipoic acid in reducing the oxidative stress induced by cyclosporine A. Clin. Chim. Acta 2006, 372:134-139.
6. Amudha G., Josephine A., Mythili Y., Sundarapandiyan R., Varalakshmi P. Therapeutic efficacy of dl-alpha-lipoic acid on cyclosporine A induced renal alterations. Eur. J. Pharmacol. 2007, 571:209-214.
7. Amudha G., Josephine A., Sudhahar V., Varalakshmi P. Protective effect of lipoic acid on oxidative and peroxidative damage in cyclosporine A-induced renal toxicity. Int. Immunopharmacol. 2007, 7:1442-1449.
8. Azevedo-Marques M.M., Hering S.E., Cupo P., et al. Acidente crotálico. Animais peçonhentos no Brasil - Clínica e terapêutica dos acidentes 2003, 91-98. Savier, São Paulo. J.L.C. Cardoso (Ed.).
9. Biewenga G.P., Haenen G.R., Bast A. The pharmacology of the antioxidant lipoic acid. Gen. Pharmacol. 1997, 29:315-331.
10. Biggs H.G., Cooper J.M. Modified folin methods for the measurement of urinary creatine and creatinine. Clin. Chem. 1961, 7:655-664.
11. Bilska A., Krvczvk A., Wlodck L. The different aspects of the biological role of glutathione. Postepy Hig. Med. Dosw. 2007, 61:438-453.
12. Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing principles of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
13. Manual de diagnóstico e tratamento de acidentes por animais peçonhentos 2001, Brasil, Ministério da Saúde, FUNASA (Fundação Nacional de Saúde), pp. 26-29.
14. Burdmann E.A. 1989. Insuficiência renal aguda por veneno de Bothrops jararaca: modelo experimental. Dissertação (doutorado) - Faculdade de Medicina de Universidade de São Paulo, São Paulo.
15. Castro I., Burdmann E.A., Seguro A.C., Yu L. Bothrops venom induces direct renal tubular injury: role for lipid peroxidation and prevention by antivenom. Toxicon 2004, 43:833-839.
16. Celik I., Cihangiroglu M., Ilhan N., Akpolat N., Akbulut H. Protective effects of different antioxidants and amrinone on vancomycin-induced nephrotoxicity. Basic Clin. Pharmacol. Toxicol. 2005, 97:325-332.
17. Cerdá J., Lameire N., Eggers P., Pannu N., Uchino S., Wang H., Bagga A., Levin A. Epidemiology of acute kidney injury. Clin. J. Am. Soc. Nephrol. 2008, 3:881-886.
18. Davenport A., Bouman C., Kirpalani A., Skippen P., Tolwani A., Mehta R.L., Palevsky P.M. Delivery of renal replacement therapy in acute kidney injury: what are the key issues?. Clin. J. Am. Soc. Nephrol. 2008, 3:869-875.
19. Ferreira S.R., Rocha A.M., Saraiva J.F. Statins in chronic renal disease. Arq. Bras. Cardiol. 2005, 85(Suppl. 5):45-49.
20. Ferreira J., Bastos M.F., Pelizon A.C., Peres C.M., Cavalcante D.P., Sartori A. Assessment of the neutralizing potency of ovine antivenom in a swiss mice model of Bothrops jararaca envenoming. J. Venom. Anim. Toxins Incl. Trop. Dis. 2005, 11:336-349.
21. Filipiak K.J., Zawadzka-Bysko M. Statins in patients with renal failure - the current therapeutic status. Przegl. Lek. 2005, 62(Suppl. 2):51-54.
22. França F.O.S. Causes of deaths in snake bites in Brazil. J. Venom. Anim. Toxins Incl. Trop. Dis. 2003, 9. "Conferences" On-line version. 1678-9199, 10.1590/S1678-91992003000200013.
23. França F.O.S., Málaque C.M.S. Acidente botrópico. Animais peçonhentos no Brasil - Clínica e terapêutica dos acidentes 2003, Savier, São Paulo. J.L.C. Cardoso (Ed.).
24. Gomes R.T., Camargo R.P., Viotti A.P., Tavares A.P., Revelo M.P., Freitas T.V. Comparison of the biodistribution of free or liposome-entrapped Crotalus durissus terrificus (South American rattlesnake) venom in mice. Comp. Biochem. Physiol. C, Toxicol. Pharmacol. 2002, 131:295-301.
25. Gonçalves D.A., Silva E.V., Graça F.A., Lira E.C., Zanon N.M., Mendes G.E., Burdmann E.A., Migliorini R.H., Kettelhut I.C., Navegantes L.C. In vivo effects of Bothrops jararaca venom on metabolic profile and on muscle protein metabolism in rats. Am. J. Trop. Med. Hyg. 2008, 79:771-778.
26. Harper C.R., Jacobson T.A. The broad spectrum of statin myopathy: from myalgia to rhabdomyolysis. Curr. Opin. Lipidol. 2007, 18:401-408.
27. Harris K.P., Lefkowith J.B., Klahr S., Schreiner G.F. Essential fatty acid deficiency ameliorates acute renal dysfunction in the rat after the administration of the aminonucleoside of puromycin. J. Clin. Invest. 1990, 86:1115-1123.
28. Kasturiratne A., Wickremasinghe A.R., de Silva N., Gunawardena N.K., Pathmeswaran A., Premaratna R., Savioli L., Lalloo D.G., de Silva H.J. The global burden of snakebite: a literature analysis and modelling based on regional estimates of envenoming and deaths. PLoS Med. 2008, 5:e218.
29. Laing G.D., Moura-da-Silva A.M. Jararhagin and its multiple effects on hemostasis. Toxicon 2005, 45:987-996.
30. Marinho C.E., Olivo R.A., Zambotti-Villela L., Ribeiro-de-Andrade T.N., Fernandes C.M., Silveira P.F. Renal and macrophage aminopeptidase activities in cyclosporin-treated mice. Int. Immunopharmacol 2006, 6:415-425.
31. Mehta R.L., Kellum J.A., Shah S.V., Molitoris B.A., Ronco C., Warnock D.G., Levin A. Acute kidney injury network. Report of an initiative to improve outcomes in acute kidney injury. Crit. Care 2007, 11:R31. Available from:. http://ccforum.com/content/11/2/R31.
32. Monteiro H.S.A., da Silva I.M.S.C., Martins A.M.C., Fonteles M.C. Actions of Crotalus durissus terrificus venom and crotoxin on the isolated rat kidney. Braz. J. Med. Biol. Res. 2001, 34:1347-1352.
33. Murugavel P., Pari L. Attenuation of chloroquine-induced renal damage by alpha-lipoic acid: possible antioxidant mechanism. Ren. Fail. 2004, 26:517-524.
34. Owczarek J., Jasinska M., Orszulak-Michalak D. Drug-induced myopathies. An overview of the possible mechanisms. Pharmacol. Rep. 2005, 57:23-34.
35. Prencipe L., Fossati P., Vanzetti G. Enzymatic determination of uric acid in serum with the trinder reaction. Quad. Sclavo Diagn. 1978, 7:655-664.
36. Rezende N.A., Amaral C.F.S., Bambirra E.A., Lachatt J.J., Coimbra T.M. Functional and histopathological renal changes induced in rats by Bothrops jararaca venom. Braz. J. Med. Biol. Res. 1989, 22:407-416.
37. Ribeiro L.A., Albuquerque M.J., de Campos V.A., Katz G., Takaoka N.Y., Lebrao M.L., Jorge M.T. Deaths caused by venomous snakes in the State of Sao Paulo: evaluation of 43 cases from 1988 to 1993. Rev. Assoc. Med. Bras. 1998, 44:312-318.
38. Santoro M.L., Sano-Martins I.S., Fan H.W., Cardoso J.L., Theakston R.D., Warrell D.A. Haematological evaluation of patients bitten by the jararaca, Bothrops jararaca, in Brazil. Toxicon 2008, 51:1440-1448. Butantan Institute Antivenom Study Group.
39. Saravia P., Rojas E., Arce V., Guevara C., López J.C., Chaves E., Rojas G., Gutiérrez J.M. Geographic and ontogenic variability in the venom of the neotropical rattlesnake Crotalus durissus: pathophysiological and therapeutic implications. Rev. Biol. Trop. 2002, 50:337-346.
40. Schmidt G.A., Hoehns J.D., Purcell J.L., Friedman R.L., Elhawi Y. Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin, amiodarone, and atazavanir. J. Am. Board Fam. Med. 2007, 20:411-416.
41. Schrier R.W., Wang W., Poole B., Mitra A. Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. J. Clin. Invest. 2004, 114:5-14.
42. Singh D., Kaur R., Chander V., Chopra K. Antioxidants in the prevention of renal disease. J. Med. Food 2006, 9:443-450.
43. Steinmetz O.M., Panzer U., Stahl R.A.K., Wenzel U.O. Statin therapy in patients with chronic kidney disease: to use or not to use. Eur. J. Clin. Invest. 2006, 36:519-527.
44. Takaoka M., Ohkita M., Kobayashi Y., Yuba M., Matsumura Y. Protective effect of alpha-lipoic acid against ischaemic acute renal failure in rats. Clin. Exp. Pharmacol. Physiol. 2002, 29:189-194.
45. Talke H., Schubert G.E. Enzymatic urea determination in the blood and serum in the Warburg optical test. Klin. Wochenschr. 1965, 43:174-175.
46. Vlahović P., Stefanović V. Kidney ectopeptidases. Structure, functions and clinical significance. Pathol. Biol. 1998, 46:779-786.
47. Yamasaki S.C., Villarroel J.S., Barone J.M., Zambotti-Villela L., Silveira P.F. Aminopeptidase activities, oxidative stress and renal function in Crotalus durissus terrificus envenomation in mice. Toxicon 2008, 52:445-454.
48. Yeter E., Keles T., Durmaz T., Bozkurt E. Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report. J. Med. Case Rep. 2007, 1:130.