Intranasal immunization with plasmid DNA encoding spike protein of SARS-coronavirus/polyethylenimine nanoparticles elicits antigen-specific humoral and cellular immune responses

BMC Immunology

Volumn 11, Issue , 2010, Pages

  Shim, Byoung Shik ^a,b   Park, Sung Moo ^a,b   Quan, Ji Shan ^a,c   Jere, Dhananjay ^a   Chu, Hyuk ^d   Song, Man K ^b   Kim, Dong W ^b   Jang, Yong Suk ^e   Yang, Moon Sik ^e   Han, Seung H ^a,b   Park, Yong Ho ^a   Cho, Chong Su ^a   Yun, Cheol Heui ^a  

^a Seoul National University   (South Korea)

^b International Vaccine Institute   (South Korea)

^c YANBIAN UNIVERSITY   (China)

^d Korea Centers for Disease Control and Prevention   (South Korea)

^e Chonbuk National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; PLASMID DNA; POLYETHYLENEIMINE; SECRETORY IMMUNOGLOBULIN; SEVERE ACUTE RESPIRATORY SYNDROME VACCINE; TUMOR NECROSIS FACTOR ALPHA; VIRUS SPIKE PROTEIN; DNA; EPITOPE; MEMBRANE ANTIGEN; MEMBRANE PROTEIN; NANOPARTICLE; SPIKE GLYCOPROTEIN, CORONAVIRUS; VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CERVICAL LYMPH NODE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DNA IMMUNIZATION; FEMALE; HUMORAL IMMUNITY; IN VITRO STUDY; LUNG LAVAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SARS CORONAVIRUS; ANIMAL; ANTIBODY PRODUCTION; B LYMPHOCYTE; BAGG ALBINO MOUSE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DRUG EFFECT; IMMUNITY; IMMUNIZATION; IMMUNOLOGY; INTRANASAL DRUG ADMINISTRATION; METHODOLOGY; PLASMID; T LYMPHOCYTE; VIROLOGY;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, VIRAL; ANTIBODY FORMATION; ANTIGENS, SURFACE; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; DENDRITIC CELLS; DNA; EPITOPES; IMMUNITY; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNIZATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; NANOPARTICLES; PLASMIDS; POLYETHYLENEIMINE; T-LYMPHOCYTES; VIRAL ENVELOPE PROTEINS;

EID: 78650672166     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-11-65     Document Type: Article

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