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Volumn 15, Issue 12, 2010, Pages 8702-8708

Platycoside N: A new oleanane-type triterpenoid saponin from the roots of platycodon grandiflorum

Author keywords

Platycodon grandiflorum; Platycoside N; Triterpenoid saponin

Indexed keywords

SAPONIN;

EID: 78650646983     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15128702     Document Type: Article
Times cited : (27)

References (26)
  • 1
    • 13744249740 scopus 로고    scopus 로고
    • Suppressive effects of Platycodon grandiflorum on the progress of carbon tetrachloride-induced hepatic fibrosis
    • Lee, K.J.; Kim, J.Y.; Jung, K.S.; Choi, C.Y.; Chung, Y.C.; Kim, D.H.; Jeong, H.G. Suppressive effects of Platycodon grandiflorum on the progress of carbon tetrachloride-induced hepatic fibrosis. Arch. Pharm. Res. 2004, 27, 1238-1244.
    • (2004) Arch. Pharm. Res. , vol.27 , pp. 1238-1244
    • Lee, K.J.1    Kim, J.Y.2    Jung, K.S.3    Choi, C.Y.4    Chung, Y.C.5    Kim, D.H.6    Jeong, H.G.7
  • 2
    • 67349162661 scopus 로고    scopus 로고
    • Inhibitory effect of platycodi radix on ovalbumin-induced airway inflammation in a murine model of asthma
    • Choi, J.H.; Hwang,Y.P.; Lee, H.S.; Jeong, H.G. Inhibitory effect of Platycodi Radix on ovalbumin-induced airway inflammation in a murine model of asthma. Food Chem. Toxicol. 2009, 47, 1272-1279.
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 1272-1279
    • Choi, J.H.1    Hwang, Y.P.2    Lee, H.S.3    Jeong, H.G.4
  • 3
    • 78049439172 scopus 로고    scopus 로고
    • Saponins from the roots of Platycodon grandiflorum stimulate osteoblast differentiation via p38 MAPK- and ERK-dependent RUNX2 activation
    • Jeong, H.M.; Han, E.H.; Jin, Y.H.; Hwang, Y.P.; Kim, H.G.; Park, B.H.; Kim, J.Y.; Chung, Y.C.; Lee, K.Y.; Jeong, H.G. Saponins from the roots of Platycodon grandiflorum stimulate osteoblast differentiation via p38 MAPK- and ERK-dependent RUNX2 activation. Food Chem. Toxicol. 2010, 48, 3362-3368.
    • (2010) Food Chem. Toxicol. , vol.48 , pp. 3362-3368
    • Jeong, H.M.1    Han, E.H.2    Jin, Y.H.3    Hwang, Y.P.4    Kim, H.G.5    Park, B.H.6    Kim, J.Y.7    Chung, Y.C.8    Lee, K.Y.9    Jeong, H.G.10
  • 4
    • 0015663795 scopus 로고
    • Pharmacological studies on Platycodon grandiflorum A. DC. IV. A comparison of experimental pharmacological effects of crude platycodin with clinical indications of platycodi radix
    • Lee, E.B. Pharmacological studies on Platycodon grandiflorum A. DC. IV. A comparison of experimental pharmacological effects of crude platycodin with clinical indications of platycodi radix. Yakugaku Zasshi 1973, 93, 1188-1194.
    • (1973) Yakugaku Zasshi , vol.93 , pp. 1188-1194
    • Lee, E.B.1
  • 5
    • 0029349124 scopus 로고
    • Effects of Platycodon grandiflorum feeding on serum and liver lipid concentrations in rats with diet-induced hyperlipidemia
    • Kim, K.S.; Ezaki, O.; Ikemoto, S.; Itakura, H. Effects of Platycodon grandiflorum feeding on serum and liver lipid concentrations in rats with diet-induced hyperlipidemia. J. Nutr. Sci. Vitaminol. 1995, 41, 485-491.
    • (1995) J. Nutr. Sci. Vitaminol. , vol.41 , pp. 485-491
    • Kim, K.S.1    Ezaki, O.2    Ikemoto, S.3    Itakura, H.4
  • 6
    • 0036515075 scopus 로고    scopus 로고
    • Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamsters
    • Shin, C.Y.; Lee, W.J.; Lee, E.B.; Choi, E.Y.; Ko, K.H. Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamsters. Planta Med. 2002, 68, 221-225.
    • (2002) Planta Med. , vol.68 , pp. 221-225
    • Shin, C.Y.1    Lee, W.J.2    Lee, E.B.3    Choi, E.Y.4    Ko, K.H.5
  • 7
    • 0034743436 scopus 로고    scopus 로고
    • Inhibition of prostaglandin E2 production by platycodin D isolated from the root of platycodon grandiflorum
    • Kim, Y.P.; Lee, E.B.; Kim, S.Y.; Li. D.; Ban, H.S.; Lim, S.S.; Shin, K.H.; Ohuchi, K. Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum. Planta Med. 2001, 67, 362-364.
    • (2001) Planta Med. , vol.67 , pp. 362-364
    • Kim, Y.P.1    Lee, E.B.2    Kim, S.Y.3    Li., D.4    Ban, H.S.5    Lim, S.S.6    Shin, K.H.7    Ohuchi, K.8
  • 8
    • 0033735626 scopus 로고    scopus 로고
    • Platycodi radix affects lipid metabolism in mice with high fat diet-induced obesity
    • Han, L.K.; Xu, B.J.; Kimura, Y.; Zheng, Y.N.; Okuda, H. Platycodi radix affects lipid metabolism in mice with high fat diet-induced obesity. J. Nutr. 2000, 130, 2760-2764.
    • (2000) J. Nutr. , vol.130 , pp. 2760-2764
    • Han, L.K.1    Xu, B.J.2    Kimura, Y.3    Zheng, Y.N.4    Okuda, H.5
  • 9
    • 0036322011 scopus 로고    scopus 로고
    • Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice
    • Han, L.K.; Zheng, Y.N.; Xu, B.J.; Okuda, H.; Kimura, Y. Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice. J. Nutr. 2002, 132, 2241-2245.
    • (2002) J. Nutr. , vol.132 , pp. 2241-2245
    • Han, L.K.1    Zheng, Y.N.2    Xu, B.J.3    Okuda, H.4    Kimura, Y.5
  • 10
    • 21844471043 scopus 로고    scopus 로고
    • In vitro inhibitory effect of triterpenoidal saponins from Platycodi Radix on pancreatic lipase
    • Xu, B.J.; Han, L.K.; Zheng, Y.N.; Lee, J.H.; Sung, C.K. In vitro inhibitory effect of triterpenoidal saponins from Platycodi Radix on pancreatic lipase. Arch. Pharm. Res. 2005, 28, 180-185.
    • (2005) Arch. Pharm. Res. , vol.28 , pp. 180-185
    • Xu, B.J.1    Han, L.K.2    Zheng, Y.N.3    Lee, J.H.4    Sung, C.K.5
  • 11
    • 16644384077 scopus 로고    scopus 로고
    • Determination of the kinetic properties of platycodin D for the inhibition of pancreatic lipase using a 1,2-diglyceride-based colorimetric assay
    • Zhao, H.L.; Kim, Y.S. Determination of the kinetic properties of platycodin D for the inhibition of pancreatic lipase using a 1,2-diglyceride-based colorimetric assay. Arch. Pharm. Res. 2004, 27, 968-972.
    • (2004) Arch. Pharm. Res. , vol.27 , pp. 968-972
    • Zhao, H.L.1    Kim, Y.S.2
  • 14
    • 59249089850 scopus 로고    scopus 로고
    • Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells
    • Shin, D.Y.; Kim, G.Y.; Li, W.; Choi, B.T.; Kim, N.D.; Kang, H.S.; Choi, Y.H. Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells. Biomed. Pharmacother. 2009, 63, 86-94.
    • (2009) Biomed. Pharmacother. , vol.63 , pp. 86-94
    • Shin, D.Y.1    Kim, G.Y.2    Li, W.3    Choi, B.T.4    Kim, N.D.5    Kang, H.S.6    Choi, Y.H.7
  • 15
    • 34247876145 scopus 로고    scopus 로고
    • Cytotoxic triterpenoid saponins from the roots of Platycodon grandiflorum
    • Zhang, L.; Liu, Z.H.; Tian, J.K. Cytotoxic triterpenoid saponins from the roots of Platycodon grandiflorum. Molecules 2007, 12, 832-841.
    • (2007) Molecules , vol.12 , pp. 832-841
    • Zhang, L.1    Liu, Z.H.2    Tian, J.K.3
  • 16
    • 77953884088 scopus 로고    scopus 로고
    • Platycodin D inhibits adipogenesis of 3T3- L1 cells by modulating kruppel-like factor 2 and peroxisome proliferator-activated receptor gamma
    • Lee, H.; Kang, R.; Kim, Y.S.; Chung, S.I.; Yoon, Y. Platycodin D inhibits adipogenesis of 3T3- L1 cells by modulating kruppel-like factor 2 and peroxisome proliferator-activated receptor gamma. Phytother. Res. 2009, 24, S161-S167
    • (2009) Phytother. Res. , vol.24
    • Lee, H.1    Kang, R.2    Kim, Y.S.3    Chung, S.I.4    Yoon, Y.5
  • 17
    • 33847294294 scopus 로고    scopus 로고
    • Antihyperglycemic effects of Platycodon grandiflorum (Jacq.) A. DC. extract on streptozotocin-induced diabetic mice
    • Zheng, J.; He, J.; Ji, B.; Li, Y.; Zhang, X. Antihyperglycemic effects of Platycodon grandiflorum (Jacq.) A. DC. extract on streptozotocin-induced diabetic mice. Plant Foods Hum. Nutr. 2007, 62, 7-11.
    • (2007) Plant Foods Hum. Nutr. , vol.62 , pp. 7-11
    • Zheng, J.1    He, J.2    Ji, B.3    Li, Y.4    Zhang, X.5
  • 18
    • 58149391410 scopus 로고    scopus 로고
    • Platyconic acid A, a genuine triterpenoid saponin from the roots of Platycodon grandiflorum
    • Choi, Y.H.; Yoo, D.S.; Choi, C.W.; Cha, M.R.; Kim, Y.S.; Lee, H.S.; Lee, K.R.; Ryu, S.Y. Platyconic acid A, a genuine triterpenoid saponin from the roots of Platycodon grandiflorum. Molecules 2008, 13, 2871-2879.
    • (2008) Molecules , vol.13 , pp. 2871-2879
    • Choi, Y.H.1    Yoo, D.S.2    Choi, C.W.3    Cha, M.R.4    Kim, Y.S.5    Lee, H.S.6    Lee, K.R.7    Ryu, S.Y.8
  • 21
    • 21344449760 scopus 로고    scopus 로고
    • Isolation of a new saponin and cytotoxic effect of saponins from the root of Platycodon grandiflorum on human tumor cell lines
    • Kim, Y.S.; Kim, J.S.; Choi, S.U.; Kim, J.S.; Lee, H.S.; Roh, S.H.; Jeong, Y.C.; Kim, Y.K.; Ryu, S.Y. Isolation of a new saponin and cytotoxic effect of saponins from the root of Platycodon grandiflorum on human tumor cell lines. Planta Med. 2005, 71, 566-568.
    • (2005) Planta Med. , vol.71 , pp. 566-568
    • Kim, Y.S.1    Kim, J.S.2    Choi, S.U.3    Kim, J.S.4    Lee, H.S.5    Roh, S.H.6    Jeong, Y.C.7    Kim, Y.K.8    Ryu, S.Y.9
  • 22
    • 33748460082 scopus 로고    scopus 로고
    • New A-ring lactone triterpenoid saponins from the roots of platycodon grandiflorum
    • Fu, W.W.; Shimizu, N.; Takeda, T.; Dou, D.Q.; Chen, B.; Pei, Y.H.; Chen, Y.J. New A-ring lactone triterpenoid saponins from the roots of Platycodon grandiflorum. Chem. Pharm. Bull. 2006, 54, 1285-1287.
    • (2006) Chem. Pharm. Bull. , vol.54 , pp. 1285-1287
    • Fu, W.W.1    Shimizu, N.2    Takeda, T.3    Dou, D.Q.4    Chen, B.5    Pei, Y.H.6    Chen, Y.J.7
  • 25
    • 34247251926 scopus 로고    scopus 로고
    • A new triterpenoid saponin from the roots of platycodon grandiflorum
    • Li, W.; Xiang, L.; Zhang, J.; Zheng, Y.N.; Han, L.K.; Saito, M. A New Triterpenoid Saponin from the Roots of Platycodon grandiflorum. Chin. Chem. Lett. 2007, 18, 306-308.
    • (2007) Chin. Chem. Lett. , vol.18 , pp. 306-308
    • Li, W.1    Xiang, L.2    Zhang, J.3    Zheng, Y.N.4    Han, L.K.5    Saito, M.6
  • 26
    • 13444302476 scopus 로고    scopus 로고
    • New triterpenoid saponins from the roots of Platycodon grandiflorum
    • DOI 10.1016/j.tet.2004.12.032, PII S0040402004020678
    • He, Z.; Qiao, C.; Han, Q.; Wang, Y.; Ye, W.; Xu, H. New triterpenoid saponins from the roots of Platycodon grandiflorum. Tetrahedron 2005, 61, 2211-2215. (Pubitemid 40203216)
    • (2005) Tetrahedron , vol.61 , Issue.8 , pp. 2211-2215
    • He, Z.1    Qiao, C.2    Han, Q.3    Wang, Y.4    Ye, W.5    Xu, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.