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Volumn 22, Issue 1, 2010, Pages 129-134

Pleiotropy in the presence of allelic heterogeneity: Alternative genetic models for the influence of APOE on serum LDL, CSF amyloid-β42, and Dementia

Author keywords

Alzheimer's disease; amyloid; association; CSF; LDL

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; APOLIPOPROTEIN E; LOW DENSITY LIPOPROTEIN;

EID: 78650645589     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-100864     Document Type: Article
Times cited : (19)

References (29)
  • 3
    • 33644857332 scopus 로고    scopus 로고
    • Does apolipoprotein e genotype influence the risk of ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage? Systematic review and meta-analyses of 31 studies among 5961 cases and 17,965 controls
    • Sudlow C, Martinez Gonzalez NA, Kim J, Clark C (2006) Does apolipoprotein E genotype influence the risk of ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage? Systematic review and meta-analyses of 31 studies among 5961 cases and 17,965 controls. Stroke 37, 364-370.
    • (2006) Stroke , vol.37 , pp. 364-370
    • Sudlow, C.1    Martinez Gonzalez, N.A.2    Kim, J.3    Clark, C.4
  • 9
    • 2942557310 scopus 로고    scopus 로고
    • APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of Abeta
    • Prince JA, Zetterberg H, Andreasen N, Marcusson J, Blennow K (2004) APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of AbetaNeurology 62, 21162118.
    • (2004) Neurology , vol.62 , pp. 21162118
    • Prince, J.A.1    Zetterberg, H.2    Andreasen, N.3    Marcusson, J.4    Blennow, K.5
  • 10
    • 1842474811 scopus 로고    scopus 로고
    • Quantitative genetic variation: A post-modern view
    • Farrall M. Quantitative genetic variation: a post-modern view (2004)HumMol Genet 1;13 Spec No 1:R1-R7.
    • (2004) HumMol Genet 1 , vol.13 , Issue.1
    • Farrall, M.1
  • 12
    • 0035147075 scopus 로고    scopus 로고
    • Robust and accurate single nu-cleotide polymorphism genotyping by dynamic allele-specific hybridization (DASH): Design criteria and assay validation
    • Prince JA, Feuk L, Howell WM, Jobs M, Emahazion T, Blennow K, Brookes AJ (2001) Robust and accurate single nu-cleotide polymorphism genotyping by dynamic allele-specific hybridization (DASH): design criteria and assay validation. GenomeRes 11, 152-162.
    • (2001) GenomeRes , vol.11 , pp. 152-162
    • Prince, J.A.1    Feuk, L.2    Howell, W.M.3    Jobs, M.4    Emahazion, T.5    Blennow, K.6    Brookes, A.J.7
  • 14
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18, 499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 15
    • 0000429149 scopus 로고
    • Modelling multivariate binary data with alternating logistic regressions
    • Carey V, Zeger SL, Diggle P (1993) Modelling multivariate binary data with alternating logistic regressions. Biometrika, 80, 517-526.
    • (1993) Biometrika , vol.80 , pp. 517-526
    • Carey, V.1    Zeger, S.L.2    Diggle, P.3
  • 16
    • 0025165779 scopus 로고
    • An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels
    • Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F (1990) An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86, 1343-1346.
    • (1990) J Clin Invest , vol.86 , pp. 1343-1346
    • Rigat, B.1    Hubert, C.2    Alhenc-Gelas, F.3    Cambien, F.4    Corvol, P.5    Soubrier, F.6
  • 20
    • 65249158083 scopus 로고    scopus 로고
    • Understanding the association of apolipoprotein E4 with Alzheimer disease: Clues from its structure
    • Zhong N, Weisgraber KH (2009) Understanding the association of apolipoprotein E4 with Alzheimer disease: clues from its structure. J Biol Chem 284, 6027-6031.
    • (2009) J Biol Chem , vol.284 , pp. 6027-6031
    • Zhong, N.1    Weisgraber, K.H.2
  • 21
    • 0025953604 scopus 로고
    • Identification of the disulfide-linked homodimer of apolipoprotein E3 in plasma. Impact on receptor binding activity
    • Weisgraber KH, Shinto LH (1991) Identification of the disulfide-linked homodimer of apolipoprotein E3 in plasma. Impact on receptor binding activity. J Biol Chem 266, 1202912034.
    • (1991) J Biol Chem , vol.266 , pp. 1202912034
    • Weisgraber, K.H.1    Shinto, L.H.2
  • 26
    • 0037465449 scopus 로고    scopus 로고
    • CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study
    • Strozyk D, Blennow K, White LR, Launer LJ (2003) CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study. Neurology 60, 652-656.
    • (2003) Neurology , vol.60 , pp. 652-656
    • Strozyk, D.1    Blennow, K.2    White, L.R.3    Launer, L.J.4
  • 27
    • 62449262536 scopus 로고    scopus 로고
    • Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain
    • Tapiola T, Alafuzoff I, Herukka SK, Parkkinen L, Hartikainen P, Soininen H, Pirttila T (2009) Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain. Arch Neurol 66, 382-389.
    • (2009) Arch Neurol , vol.66 , pp. 382-389
    • Tapiola, T.1    Alafuzoff, I.2    Herukka, S.K.3    Parkkinen, L.4    Hartikainen, P.5    Soininen, H.6    Pirttila, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.