A novel method for stereospecific fluorination at the 2′-arabino- position of pyrimidine nucleoside: Synthesis of [18F]-FMAU

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 53, Issue 13, 2010, Pages 782-786

  Turkman, Nashaat ^a   Gelovani, Juri G ^a   Alauddin, Mian M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Fluorine 18; PET; pyrimidine nucleoside; stereospecific fluorination

Indexed keywords

AROMATIC COMPOUNDS; BIOMOLECULES; FLUORINE; HALOGENATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

2-DEOXY-2; ARABINOS; DIRECT FLUORINATION; FLUORINE-18; NOVEL METHODS; NUCLEOSIDE ANALOGS; PYRIMIDINE NUCLEOSIDES; STEREOSPECIFIC; STEREOSPECIFIC FLUORINATION; TETRAHYDROPYRANYL;

FLUORINATION;

2' METHYLSULFONYL 3',5' O TETRAHYDROPYRANYL N 3 BOC 5 METHYL 1 BETA DEXTRO RIBOFURANOSILURACIL F 18; 5 ETHYL 2' FLUOROURACIL ARABINOSIDE F 18; CLEVUDINE; CLEVUDINE F 18; DRUG METABOLITE; FIALURIDINE F 18; FLUORINE 18; PYRIMIDINE NUCLEOSIDE; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; ISOTOPE LABELING; RADIOCHEMISTRY; RADIOISOTOPE DECAY; STEREOSPECIFICITY; SUBSTITUTION REACTION; THIN LAYER CHROMATOGRAPHY;

EID: 78650641634     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1797     Document Type: Article

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