Transmission of classical swine fever virus depends on the clinical course of infection which is associated with high and low levels of virus excretion

Veterinary Microbiology

Volumn 147, Issue 3-4, 2011, Pages 262-273

  Weesendorp, Eefke ^a,b   Backer, Jantien ^a   Stegeman, Arjan ^b   Loeffen, Willie ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Classical swine fever; Courses of infection; CSFV contaminated environment; One to one experiments; Transmission parameters

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CLASSICAL SWINE FEVER; DISEASE COURSE; INOCULATION; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; VIRUS EXCRETION; VIRUS INFECTION; VIRUS TRANSMISSION;

ANIMALS; CLASSICAL SWINE FEVER; CLASSICAL SWINE FEVER VIRUS; ENVIRONMENT; FECES; OROPHARYNX; SWINE; VIRUS SHEDDING;

CLASSICAL SWINE FEVER VIRUS; SUIDAE;

EID: 78650580814     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetmic.2010.06.032     Document Type: Article

References (34)

1. Bouma A., De Smit A.J., De Kluijver E.P., Terpstra C., Moormann R.J. Efficacy and stability of a subunit vaccine based on glycoprotein E2 of classical swine fever virus. Vet. Microbiol. 1999, 66:101-114.
2. Colijn E.O., Bloemraad M., Wensvoort G. An improved ELISA for the detection of serum antibodies directed against classical swine fever virus. Vet. Microbiol. 1997, 59:15-25.
3. De Jong M.C., Kimman T.G. Experimental quantification of vaccine-induced reduction in virus transmission. Vaccine 1994, 12:761-766.
4. Dewulf J., Laevens H., Koenen F., Mintiens K., De Kruif A. Airborne transmission of classical swine fever virus under experimental conditions. Vet. Rec. 2000, 147:735-738.
5. Dewulf J., Laevens H., Koenen F., Mintiens K., De Kruif A. An experimental infection to investigate the indirect transmission of classical swine fever virus by excretions of infected pigs. J. Vet. Med. B Infect. Dis. Vet. Public Health 2002, 49:452-456.
6. Diekmann O., Heesterbeek J.A.P. Mathematical Epidemiology of Infectious diseases: model building, analysis and interpretation 2000, John Wiley and Sons Chichester.
7. Dortmans J.C., Loeffen W.L., Weerdmeester K., Van der Poel W.H., De Bruin M.G. Efficacy of intradermally administrated E2 subunit vaccines in reducing horizontal transmission of classical swine fever virus. Vaccine 2008, 26:1235-1242.
8. Durand B., Davila S., Cariolet R., Mesplede A., Le Potier M.F. Comparison of viraemia- and clinical-based estimates of within- and between -pen transmission of classical swine fever virus from three transmission experiments. Vet. Microbiol. 2009, 135:196-204.
9. Eble P.L., Bouma A., Weerdmeester K., Stegeman J.A., Dekker A. Serological and mucosal immune responses after vaccination and infection with FMDV in pigs. Vaccine 2007, 25:1043-1054.
10. Finney D.J. Statistical Methods in Biological Assay 1978, Charles Griffin & Company LTD London.
11. Floegel-Niesmann G., Bunzenthal C., Fischer S., Moennig V. Virulence of recent and former classical swine fever virus isolates evaluated by their clinical and pathological signs. J. Vet. Med. B Infect. Dis. Vet. Public Health 2003, 50:214-220.
12. Greiser-Wilke I., Fritzemeier J., Koenen F., Vanderhallen H., Rutili D., De Mia G.M., Romero L., Rosell R., Sanchez-Vizcaino J.M., San Gabriel A. Molecular epidemiology of a large classical swine fever epidemic in the European Union in 1997-1998. Vet. Microbiol. 2000, 77:17-27.
13. Harkness J.W. Classical swine fever and its diagnosis: a current view. Vet. Rec. 1985, 116:288-293.
14. Kaden V., Lange E., Polster U., Klopfleisch R., Teifke J.P. Studies on the virulence of two field isolates of the classical Swine Fever virus genotype 2.3 Rostock in wild boars of different age groups. J. Vet. Med. B Infect. Dis. Vet. Public Health 2004, 51:202-208.
15. Keeling M.J., Rohani P. Modeling Infectious Diseases in Humans and Animals 2008, Princeton University Press Princeton.
16. Klinkenberg, D., Bouma, A. Floegel-Niesmann, G., De Jong, M.C., 2003. E2 subunit marker vaccines reduce transmission of classical swine fever virus sufficiently to halt epidemics. Mathematical epidemiology the control of classical swine fever virus, Ph.D. thesis, University of Utrecht, The Netherlands, pp. 37-60.
17. Lindenbach B.D., Rice C.M. Flaviviridae: the virus and their replication. Fields Virology 2001, 991-1042. Lippincott Williams & Wilkins, Philadelphia. D.M. Knipe, P.M. Howley (Eds.).
18. Meuwissen M.P., Horst S.H., Huirne R.B., Dijkhuizen A.A. A model to estimate the financial consequences of classical swine fever outbreaks: principles and outcomes. Prev. Vet. Med. 1999, 42:249-270.
19. Mittelholzer C., Moser C., Tratschin J.D., Hofmann M.A. Analysis of classical swine fever virus replication kinetics allows differentiation of highly virulent from avirulent strains. Vet. Microbiol. 2000, 74:293-308.
20. Moennig V. Introduction to classical swine fever: virus, disease and control policy. Vet. Microbiol. 2000, 73:93-102.
21. Ribbens S., Dewulf J., Koenen F., Laevens H., Mintiens K., De Kruif A. An experimental infection (II) to investigate the importance of indirect classical swine fever virus transmission by excretions and secretions of infected weaner pigs. J. Vet. Med. B Infect. Dis. Vet. Public Health 2004, 51:438-442.
22. Stewart W.C., Downing D.R., Carbrey E.A., Kresse J.I., Snyder M.L. Thermal inactivation of hog cholera virus in ham. Am. J. Vet. Res. 1979, 40:739-741.
23. Terpstra C., De Smit A.J. The 1997/1998 epizootic of swine fever in the Netherlands: control strategies under a non-vaccination regimen. Vet. Microbiol. 2000, 77:3-15.
24. Uttenthal A., Le Potier M.F., Romero L., De Mia G.M., Floegel-Niesmann G. Classical swine fever (CSF) marker vaccine. Trial I. Challenge studies in weaner pigs. Vet. Microbiol. 2001, 83:85-106.
25. Uttenthal A., Storgaard T., Oleksiewicz M.B., De Stricker K. Experimental infection with the Paderborn isolate of classical swine fever virus in 10-week-old pigs: determination of viral replication kinetics by quantitative RT-PCR, virus isolation and antigen ELISA. Vet. Microbiol. 2003, 92:197-212.
26. Van Oirschot J.T. Description of the virus infection. Classical Swine Fever and Related Viral Infections 1988, 1-25. Martinus Nijhoff Publishing, Dordrecht. B. Liess (Ed.).
27. Van Rijn P.A., Wellenberg G.J., Hakze-van der Honing R., Jacobs L., Moonen P.L., Feitsma H. Detection of economically important viruses in boar semen by quantitative RealTime PCR technology. J. Virol. Methods 2004, 120:151-160.
28. Vandeputte J., Chappuis G. Classical swine fever: the European experience and a guide for infected areas. Rev. Sci. Technol. 1999, 18:638-647.
29. Velthuis A.G., Bouma A., Katsma W.E., Nodelijk G., De Jong M.C. Design and analysis of small-scale transmission experiments with animals. Epidemiol. Infect. 2007, 135:202-217.
30. Weesendorp E., Backer J., Stegeman A., Loeffen W. Effect of strain and inoculation dose of classical swine fever virus on within-pen transmission. Vet. Res. 2009, 40:59.
31. Weesendorp E., Landman W.J., Stegeman A., Loeffen W.L. Detection and quantification of classical swine fever virus in air samples originating from infected pigs and experimentally produced aerosols. Vet. Microbiol. 2008, 127:50-62.
32. Weesendorp E., Stegeman A., Loeffen W. Survival of classical swine fever virus at various temperatures in faeces and urine derived from experimentally infected pigs. Vet. Microbiol. 2008, 132:249-259.
33. Weesendorp E., Stegeman A., Loeffen W. Dynamics of virus excretion via different routes in pigs experimentally infected with classical swine fever virus strains of high, moderate or low virulence. Vet. Microbiol. 2009, 133:9-22.
34. Wensvoort G., Terpstra C., Boonstra J., Bloemraad M., Van Zaane D. Production of monoclonal antibodies against swine fever virus and their use in laboratory diagnosis. Vet. Microbiol. 1986, 12:101-108.