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Volumn 28, Issue 5 SUPPL. 61, 2010, Pages

Underestimation of the efficacy, effectiveness, tolerability, and safety of weekly low-dose methotrexate in information presented to physicians and patients

Author keywords

Effectiveness; Efficacy; Low dose; Methotrexate; Weekly low dose

Indexed keywords

ACETYLSALICYLIC ACID; ANTIMALARIAL AGENT; AURANOFIN; AZATHIOPRINE; BIOLOGICAL PRODUCT; CORTICOSTEROID; CYCLOSPORIN; DISEASE MODIFYING ANTIRHEUMATIC DRUG; ETANERCEPT; FOLIC ACID; GLUCOCORTICOID; GOLD; HYDROXYCHLOROQUINE; IBUPROFEN; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; LEFLUNOMIDE; METHOTREXATE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PENICILLAMINE; PLACEBO; PREDNISONE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SALAZOSULFAPYRIDINE; SALICYLIC ACID DERIVATIVE; TUMOR NECROSIS FACTOR INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; ABATACEPT; ADALIMUMAB; ANAKINRA; CERTOLIZUMAB PEGOL; GOLIMUMAB; RITUXIMAB; SALICYLIC ACID; TOCILIZUMAB;

EID: 78650574250     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (27)

References (114)
  • 2
    • 67549096874 scopus 로고    scopus 로고
    • Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: Integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative
    • VISSER K, KATCHAMART W, LOZA E et al.: Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative. Ann Rheum Dis 2009;68:1086-93.
    • (2009) Ann. Rheum. Dis. , vol.68 , pp. 1086-1093
    • Visser, K.1    Katchamart, W.2    Loza, E.3
  • 3
    • 2442590862 scopus 로고    scopus 로고
    • New drugs for rheumatoid arthritis
    • OLSEN NJ, STEIN CM: New drugs for rheumatoid arthritis. N Engl J Med 2004;350:2167-79.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2167-2179
    • Olsen, N.J.1    Stein, C.M.2
  • 5
    • 0027077654 scopus 로고
    • Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second line drugs and prednisone
    • PINCUS T, MARCUM SB, CALLAHAN LF: Long-term drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second-line drugs and prednisone. J Rheumatol 1992;19:1885-94. (Pubitemid 23018519)
    • (1992) Journal of Rheumatology , vol.19 , Issue.12 , pp. 1885-1894
    • Pincus, T.1    Marcum, S.B.2    Callahan, L.F.3
  • 6
    • 33846090262 scopus 로고    scopus 로고
    • Retention rates of TNF blockers in daily practice in 770 rheumatic patients
    • DUCLOS M, GOSSEC L, RUYSSEN-WITRAND A et al.: Retention rates of TNF blockers in daily practice in 770 rheumatic patients. J Rheumatol 2006;33:2433-9.
    • (2006) J. Rheumatol. , vol.33 , pp. 2433-2439
    • Duclos, M.1    Gossec, L.2    Ruyssen-Witrand, A.3
  • 7
    • 13244295795 scopus 로고    scopus 로고
    • Long term safety of methotrexate in routine clinical care: Discontinuation is unusual and rarely the result of laboratory abnormalities
    • YAZICI Y, SOKKA T, KAUTIAINEN H, SWEARINGEN C, KULMAN I, PINCUS T: Long term safety of methotrexate in routine clinical care: discontinuation is unusual and rarely the result of laboratory abnormalities. Ann Rheum Dis 2005;64:207-11.
    • (2005) Ann. Rheum. Dis. , vol.64 , pp. 207-211
    • Yazici, Y.1    Sokka, T.2    Kautiainen, H.3    Swearingen, C.4    Kulman, I.5    Pincus, T.6
  • 8
    • 0021212076 scopus 로고
    • Severe functional declines, work disability, and increased mortality in seventy-five rheumatoid arthritis patients studied over nine years
    • PINCUS T, CALLAHAN LF, SALE WG, BROOKS AL, PAYNE LE, VAUGHN WK: Severe functional declines, work disability, and increased mortality in seventy-five rheumatoid arthritis patients studied over nine years. Arthritis Rheum 1984;27:864-72.
    • (1984) Arthritis Rheum. , vol.27 , pp. 864-872
    • Pincus, T.1    Callahan, L.F.2    Sale, W.G.3    Brooks, A.L.4    Payne, L.E.5    Vaughn, W.K.6
  • 9
    • 0021385327 scopus 로고
    • The natural history of rheumatoid arthritis: A fifteen year followup study. The prognostic significance of features noted in the first year
    • RASKER JJ, COSH JA: The natural history of rheumatoid arthritis: a fifteen year followup study. The prognostic significance of features noted in the first year. Clin Rheumatol 1984;3:11-20.
    • (1984) Clin. Rheumatol. , vol.3 , pp. 11-20
    • Rasker, J.J.1    Cosh, J.A.2
  • 11
    • 34147213100 scopus 로고    scopus 로고
    • Stable occurrence of knee and hip total joint replacement in Central Finland between 1986 and 2003: An indication of improved long-term outcomes of rheumatoid arthritis
    • SOKKA T, KAUTIAINEN H, HANNONEN P: Stable occurrence of knee and hip total joint replacement in Central Finland between 1986 and 2003: an indication of improved long-term outcomes of rheumatoid arthritis. Ann Rheum Dis 2007;66:341-4.
    • (2007) Ann. Rheum. Dis. , vol.66 , pp. 341-344
    • Sokka, T.1    Kautiainen, H.2    Hannonen, P.3
  • 12
    • 0018950994 scopus 로고
    • Work disability in rheumatoid arthritis: Effects of disease, social, and work factors
    • YELIN E, MEENAN R, NEVITT M, EPSTEIN W: Work disability in rheumatoid arthritis: effects of disease, social, and work factors. Ann Intern Med 1980;93:551-6.
    • (1980) Ann. Intern. Med. , vol.93 , pp. 551-556
    • Yelin, E.1    Meenan, R.2    Nevitt, M.3    Epstein, W.4
  • 14
    • 0032996188 scopus 로고    scopus 로고
    • Lower disease activity and disability in Swedish patients with rheumatoid arthritis in 1995 compared with 1978
    • BERGSTROM U, BOOK C, LINDROTH Y, MARSAL L, SAXNE T, JACOBSSON L: Lower disease activity and disability in Swedish patients with rheumatoid arthritis in 1995 compared with 1978. Scand J Rheumatol 1999;28:160-5.
    • (1999) Scand. J. Rheumatol. , vol.28 , pp. 160-165
    • Bergstrom, U.1    Book, C.2    Lindroth, Y.3    Marsal, L.4    Saxne, T.5    Jacobsson, L.6
  • 15
    • 0032848738 scopus 로고    scopus 로고
    • Conventional monotherapy compared to a "sawtooth" treatment strategy in the radiographic procession of rheumatoid arthritis over the first eight years
    • SOKKA TM, KAARELA K, MOTTONEN TT, HANNONEN PJ: Conventional monotherapy compared to a "sawtooth" treatment strategy in the radiographic procession of rheumatoid arthritis over the first eight years. Clin Exp Rheumatol 1999;17:527-32.
    • (1999) Clin. Exp. Rheumatol. , vol.17 , pp. 527-532
    • Sokka, T.M.1    Kaarela, K.2    Mottonen, T.T.3    Hannonen, P.J.4
  • 16
    • 0142243119 scopus 로고    scopus 로고
    • Reduction in longterm functional disability in rheumatoid arthritis from 1977 to 1998: A longitudinal study of 3035 patients
    • KRISHNAN E, FRIES JF: Reduction in longterm functional disability in rheumatoid arthritis from 1977 to 1998: a longitudinal study of 3035 patients. Am J Med 2003;115:371-6.
    • (2003) Am. J. Med. , vol.115 , pp. 371-376
    • Krishnan, E.1    Fries, J.F.2
  • 17
    • 2642548887 scopus 로고    scopus 로고
    • Radiographic progression is getting milder in patients with early rheumatoid arthritis. Results of 3 cohorts over 5 years
    • SOKKA T, KAUTIAINEN H, HÄKKINEN K, HANNONEN P: Radiographic progression is getting milder in patients with early rheumatoid arthritis. Results of 3 cohorts over 5 years. J Rheumatol 2004;31:1073-82.
    • (2004) J. Rheumatol. , vol.31 , pp. 1073-1082
    • Sokka, T.1    Kautiainen, H.2    Häkkinen, K.3    Hannonen, P.4
  • 18
    • 17244380041 scopus 로고    scopus 로고
    • Patients seen for standard rheumatoid arthritis care have significantly better articular, radiographic, laboratory, and functional status in 2000 than in 1985
    • PINCUS T, SOKKA T, KAUTIAINEN H: Patients seen for standard rheumatoid arthritis care have significantly better articular, radiographic, laboratory, and functional status in 2000 than in 1985. Arthritis Rheum 2005;52:1009-19.
    • (2005) Arthritis Rheum. , vol.52 , pp. 1009-1019
    • Pincus, T.1    Sokka, T.2    Kautiainen, H.3
  • 19
    • 0034083138 scopus 로고    scopus 로고
    • Response to methotrexate treatment is associated with reduced mortality in patients with severe rheumatoid arthritis
    • KRAUSE D, SCHLEUSSER B, HERBORN G, RAU R: Response to methotrexate treatment is associated with reduced mortality in patients with severe rheumatoid arthritis. Arthritis Rheum 2000;43:14-21.
    • (2000) Arthritis Rheum. , vol.43 , pp. 14-21
    • Krause, D.1    Schleusser, B.2    Herborn, G.3    Rau, R.4
  • 20
    • 0037029418 scopus 로고    scopus 로고
    • Methotrexate and mortality in patients with rheumatoid arthritis: A prospective study
    • CHOI HK, HERNÁN MA, SEEGER JD, ROBINS JM, WOLFE F: Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study. Lancet 2002;359:1173-7.
    • (2002) Lancet , vol.359 , pp. 1173-1177
    • Choi, H.K.1    Hernán, M.A.2    Seeger, J.D.3    Robins, J.M.4    Wolfe, F.5
  • 21
    • 0024673211 scopus 로고
    • Remodeling the pyramid - A concept whose time has come
    • WILSKE KR, HEALEY LA: Remodeling the pyramid - a concept whose time has come. J Rheumatol 1989;16:565-7.
    • (1989) J. Rheumatol. , vol.16 , pp. 565-567
    • Wilske, K.R.1    Healey, L.A.2
  • 22
    • 0025648429 scopus 로고
    • Remodeling the pyramid or remodeling the paradigms concerning rheumatoid arthritis - Lessons from Hodgkin's disease and coronary artery disease
    • PINCUS T, CALLAHAN LF: Remodeling the pyramid or remodeling the paradigms concerning rheumatoid arthritis - lessons from Hodgkin's disease and coronary artery disease. J Rheumatol 1990;17:1582-5.
    • (1990) J. Rheumatol. , vol.17 , pp. 1582-1585
    • Pincus, T.1    Callahan, L.F.2
  • 23
    • 0025308298 scopus 로고
    • Reevaluating the therapeutic approach to rheumatoid arthritis: The "sawtooth" strategy
    • FRIES JF: Reevaluating the therapeutic approach to rheumatoid arthritis: the "sawtooth" strategy. J Rheumatol 1990;17(Suppl. 22):12-5.
    • (1990) J. Rheumatol. , vol.17 , Issue.22 SUPPL. , pp. 12-15
    • Fries, J.F.1
  • 24
    • 0026587874 scopus 로고
    • The case for early intervention in rheumatoid arthritis
    • PINCUS T: The case for early intervention in rheumatoid arthritis. J Autoimmun 1992;5(Suppl. A): 209-26.
    • (1992) J. Autoimmun , vol.5 , Issue.SUPPL. A , pp. 209-226
    • Pincus, T.1
  • 25
    • 0028586878 scopus 로고
    • Rheumatoid arthritis: A medical emergency?
    • PINCUS T: Rheumatoid arthritis: A medical emergency? Scand J Rheumatol 1994;23(Suppl. 100):21-30.
    • (1994) Scand. J. Rheumatol. , vol.23 , Issue.100 SUPPL. , pp. 21-30
    • Pincus, T.1
  • 26
    • 0028866438 scopus 로고
    • Early rheumatoid arthritis: Time to aim for remission?
    • EMERY P, SALMON M: Early rheumatoid arthritis: time to aim for remission? Ann Rheum Dis 1995;54:944-7.
    • (1995) Ann. Rheum. Dis. , vol.54 , pp. 944-947
    • Emery, P.1    Salmon, M.2
  • 27
    • 0029993687 scopus 로고    scopus 로고
    • Rheumatoid arthritis: Treat now, not later! (editorial)
    • WEINBLATTME: Rheumatoid arthritis: Treat now, not later! (editorial). Ann Intern Med 1996;124:773-4.
    • (1996) Ann. Intern. Med. , vol.124 , pp. 773-774
    • Weinblattme1
  • 28
    • 0032701832 scopus 로고    scopus 로고
    • Targeted therapies in rheumatoid arthritis: The need for action
    • EMERY P, PANAYI G, STURROCK R, WILLIAMS B: Targeted therapies in rheumatoid arthritis: The need for action. Rheumatology 1999;38:911-2.
    • (1999) Rheumatology , vol.38 , pp. 911-912
    • Emery, P.1    Panayi, G.2    Sturrock, R.3    Williams, B.4
  • 29
    • 4944234742 scopus 로고    scopus 로고
    • Relative versus absolute goals of therapies for RA: ACR 20 or ACR 50 responses versus target values for "near remission" of DAS or single measures
    • PINCUS T, SOKKA T, KAVANAUGH A: Relative versus absolute goals of therapies for RA: ACR 20 or ACR 50 responses versus target values for "near remission" of DAS or single measures. Clin Exp Rheumatol 2004;22(Suppl. 35): S50-S56.
    • (2004) Clin. Exp. Rheumatol. , vol.22 , Issue.35 SUPPL.
    • Pincus, T.1    Sokka, T.2    Kavanaugh, A.3
  • 30
    • 77950307115 scopus 로고    scopus 로고
    • Treating rheumatoid arthritis to target: Recommendations of an international task force
    • SMOLEN JS, ALETAHA D, BULSMA JW et al.: Treating rheumatoid arthritis to target: recommendations of an international task force. Ann Rheum Dis 2010;69:631-7.
    • (2010) Ann. Rheum. Dis. , vol.69 , pp. 631-637
    • Smolen, J.S.1    Aletaha, D.2    Bulsma, J.W.3
  • 32
    • 0026538805 scopus 로고
    • Trends in the incidence and severity of rheumatoid arthritis
    • SILMAN AJ: Trends in the incidence and severity of rheumatoid arthritis. J Rheumatol 1992;19(Suppl. 32):71-3.
    • (1992) J. Rheumatol. , vol.19 , Issue.32 SUPPL. , pp. 71-73
    • Silman, A.J.1
  • 33
    • 33645080670 scopus 로고    scopus 로고
    • Has rheumatoid arthritis become a milder disease?
    • UHLIG T, KVIEN TK: Has rheumatoid arthritis become a milder disease? Drug Discovery Today 2005;2:331-6.
    • (2005) Drug Discovery Today , vol.2 , pp. 331-336
    • Uhlig, T.1    Kvien, T.K.2
  • 34
    • 0025084541 scopus 로고
    • The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis: Results of two metaanalyses
    • FELSON DT, ANDERSON JJ, MEENAN RF: The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis: results of two metaanalyses. Arthritis Rheum 1990;33:1449-61.
    • (1990) Arthritis Rheum. , vol.33 , pp. 1449-1461
    • Felson, D.T.1    Anderson, J.J.2    Meenan, R.F.3
  • 35
    • 52949096940 scopus 로고    scopus 로고
    • Ascendancy of weekly low-dose methotrexate in usual care of rheumatoid arthritis from 1980 to 2004 at two sites in Finland and the United States
    • SOKKA T, PINCUS T: Ascendancy of weekly low-dose methotrexate in usual care of rheumatoid arthritis from 1980 to 2004 at two sites in Finland and the United States. Rheumatology (Oxford) 2008;47:1543-7.
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 1543-1547
    • Sokka, T.1    Pincus, T.2
  • 36
    • 0026579862 scopus 로고
    • Comparison of auranofin, methotrexate, and the combination of both in the treatment of rheumatoid arthritis: A controlled clinical trial
    • WILLIAMS HJ, WARD JR, READING JC et al.: Comparison of auranofin, methotrexate, and the combination of both in the treatment of rheumatoid arthritis: a controlled clinical trial. Arthritis Rheum 1992;35:259-69.
    • (1992) Arthritis Rheum. , vol.35 , pp. 259-269
    • Williams, H.J.1    Ward, J.R.2    Reading, J.C.3
  • 37
    • 38749141455 scopus 로고    scopus 로고
    • Systematic review: Comparative effectiveness and harms of disease-modifying medications for rheumatoid arthritis
    • DONAHUE KE, GARTLEHNER G, JONAS DE et al.: Systematic review: comparative effectiveness and harms of disease-modifying medications for rheumatoid arthritis. Ann Intern Med 2008;148:124-34.
    • (2008) Ann. Intern. Med. , vol.148 , pp. 124-134
    • Donahue, K.E.1    Gartlehner, G.2    Jonas, D.E.3
  • 38
    • 33144490691 scopus 로고    scopus 로고
    • Grading strength of recommendations and quality of evidence in clinical guidelines: Report from an American College of Chest Physicians task force
    • DOI 10.1378/chest.129.1.174
    • GUYATT G, GUTTERMAN D, BAUMANN MH et al.: Grading strength of recommendations and quality of evidence in clinical guidelines: report from an american college of chest physicians task force. Chest 2006;129:174-81. (Pubitemid 43265259)
    • (2006) Chest , vol.129 , Issue.1 , pp. 174-181
    • Guyatt, G.1    Gutterman, D.2    Baumann, M.H.3    Addrizzo-Harris, D.4    Hylek, E.M.5    Phillips, B.6    Raskob, G.7    Lewis, S.Z.8    Schunemann, H.9
  • 39
    • 44849143594 scopus 로고    scopus 로고
    • Are excellent systematic reviews of clinical trials useful for patient care?
    • PINCUS T, YAZICI Y, SOKKA T: Are excellent systematic reviews of clinical trials useful for patient care? Nat Clin Pract Rheumatol 2008;4:294-5.
    • (2008) Nat. Clin. Pract. Rheumatol. , vol.4 , pp. 294-295
    • Pincus, T.1    Yazici, Y.2    Sokka, T.3
  • 40
    • 5444228476 scopus 로고    scopus 로고
    • Clinical trials in rheumatic diseases: Designs and limitations
    • PINCUS T, SOKKA T: Clinical trials in rheumatic diseases: designs and limitations. Rheum Dis Clin N Am 2004;30:701-4.
    • (2004) Rheum. Dis. Clin. N. Am. , vol.30 , pp. 701-704
    • Pincus, T.1    Sokka, T.2
  • 41
    • 0018076475 scopus 로고
    • The importance of beta, the type II error and sample size in the design and interpretation of the randomized control trial: Survey of 71 "negative" trials
    • FREIMAN JA, CHALMERS TC, SMITH H, JR, KUEBLER RR: The importance of beta, the type II error and sample size in the design and interpretation of the randomized control trial: survey of 71 "negative" trials. N Engl J Med 1978;299:690-4.
    • (1978) N. Engl. J. Med. , vol.299 , pp. 690-694
    • Freiman, J.A.1    Chalmers, T.C.2    Smith Jr., H.3    Kuebler, R.R.4
  • 42
    • 0003265554 scopus 로고
    • The randomized clinical trial as an obstacle to clinical research
    • VARCO RL, DELANEY JP Eds.:, Philadelphia, Saunders. W. B.
    • FREIREICH EJ: The randomized clinical trial as an obstacle to clinical research. In: VARCO RL, DELANEY JP (Eds.): Controversy in Surgery. Philadelphia, Saunders. W. B., 1983, pp. 5-12.
    • (1983) Controversy in Surgery , pp. 5-12
    • Freireich, E.J.1
  • 43
    • 0020561780 scopus 로고
    • An additional basic science for clinical medicine: II. The limitations of randomized trials
    • FEINSTEIN AR: An additional basic science for clinical medicine: II. The limitations of randomized trials. Ann Intern Med 1983;99:544-50.
    • (1983) Ann. Intern. Med. , vol.99 , pp. 544-550
    • Feinstein, A.R.1
  • 44
    • 0029023726 scopus 로고
    • Can overall results of clinical trials be applied to all patients?
    • ROTHWELL PM: Can overall results of clinical trials be applied to all patients? Lancet 1995;345:1616-9.
    • (1995) Lancet , vol.345 , pp. 1616-1619
    • Rothwell, P.M.1
  • 45
    • 0031472453 scopus 로고    scopus 로고
    • Problems in the "evidence" of "evidence-based medicine"
    • FEINSTEIN AR, HORWITZ RI: Problems in the "evidence" of "evidence-based medicine". Am J Med 1997;103:529-35.
    • (1997) Am. J. Med. , vol.103 , pp. 529-535
    • Feinstein, A.R.1    Horwitz, R.I.2
  • 46
    • 0035021115 scopus 로고    scopus 로고
    • The double-blind, randomized, placebo-controlled trial: Gold standard or golden calf?
    • KAPTCHUK TJ: The double-blind, randomized, placebo-controlled trial: gold standard or golden calf? J Clin Epidemiol 2001;54:541-9.
    • (2001) J. Clin. Epidemiol. , vol.54 , pp. 541-549
    • Kaptchuk, T.J.1
  • 47
    • 23844472994 scopus 로고    scopus 로고
    • Evidence from clinical trials: Can we do better?
    • SIDEROWF AD: Evidence from clinical trials: can we do better? NeuroRx 2004;1:363-71.
    • (2004) NeuroRx , vol.1 , pp. 363-371
    • Siderowf, A.D.1
  • 48
    • 33744462066 scopus 로고    scopus 로고
    • The limitations of 'evidence-based' public health
    • KEMM J: The limitations of 'evidence-based' public health. J Eval Clin Pract 2006;12:319-24.
    • (2006) J. Eval Clin. Pract. , vol.12 , pp. 319-324
    • Kemm, J.1
  • 49
    • 35148898782 scopus 로고    scopus 로고
    • Clinical trials versus registries in coronary revascularization: Which are more relevant?
    • MACK MJ: Clinical trials versus registries in coronary revascularization: which are more relevant? Curr Opin Cardiol 2007;22:524-8.
    • (2007) Curr. Opin. Cardiol. , vol.22 , pp. 524-528
    • Mack, M.J.1
  • 50
    • 34547172234 scopus 로고    scopus 로고
    • Limitations of the randomized controlled trial in evaluating population-based health interventions
    • SANSON-FISHER RW, BONEVSKI B, GREEN LW, D'ESTE C: Limitations of the randomized controlled trial in evaluating population-based health interventions. Am J Prev Med 2007;33:155-61.
    • (2007) Am. J. Prev. Med. , vol.33 , pp. 155-161
    • Sanson-Fisher, R.W.1    Bonevski, B.2    Green, L.W.3    D'Este, C.4
  • 51
    • 2442649987 scopus 로고    scopus 로고
    • When are observational studies as credible as randomised trials?
    • VANDENBROUCKE J: When are observational studies as credible as randomised trials? Lancet 2004;363:1728-31.
    • (2004) Lancet , vol.363 , pp. 1728-1731
    • Vandenbroucke, J.1
  • 52
    • 0024208901 scopus 로고
    • Rheumatoid arthritis: Disappointing long-term outcomes despite successful short-term clinical trials
    • PINCUS T: Rheumatoid arthritis: disappointing long-term outcomes despite successful short-term clinical trials. J Clin Epidemiol 1988;41:1037-41.
    • (1988) J. Clin. Epidemiol. , vol.41 , pp. 1037-1041
    • Pincus, T.1
  • 53
    • 85044498299 scopus 로고
    • Response to letter: Gold therapy for rheumatoid arthritis: Challenges to traditional paradigms
    • PINCUS T, WOLFE F: Response to letter: Gold therapy for rheumatoid arthritis: Challenges to traditional paradigms. Ann Intern Med 1992;117:169-70.
    • (1992) Ann. Intern. Med. , vol.117 , pp. 169-170
    • Pincus, T.1    Wolfe, F.2
  • 54
    • 0027786835 scopus 로고
    • Limitations of randomized controlled clinical trials to recognize possible advantages of combination therapies in rheumatic diseases
    • PINCUS T: Limitations of randomized controlled clinical trials to recognize possible advantages of combination therapies in rheumatic diseases. Semin Arthritis Rheum 1993;23(Suppl. 1):2-10.
    • (1993) Semin. Arthritis Rheum. , vol.23 , Issue.1 SUPPL. , pp. 2-10
    • Pincus, T.1
  • 55
    • 0029162483 scopus 로고
    • What is the best source of useful data on the treatment of rheumatoid arthritis: Clinical trials, clinical observations, or clinical protocols?
    • PINCUS T, STEIN M: What is the best source of useful data on the treatment of rheumatoid arthritis: Clinical trials, clinical observations, or clinical protocols? J Rheumatol 1995;22:1611-7.
    • (1995) J. Rheumatol. , vol.22 , pp. 1611-1617
    • Pincus, T.1    Stein, M.2
  • 56
    • 0002525514 scopus 로고    scopus 로고
    • Analyzing long-term outcomes of clinical care without randomized controlled clinical trials: The consecutive patient questionnaire database
    • PINCUS T: Analyzing long-term outcomes of clinical care without randomized controlled clinical trials: The consecutive patient questionnaire database. Advances 1997;13:3-32.
    • (1997) Advances , vol.13 , pp. 3-32
    • Pincus, T.1
  • 57
    • 0030874291 scopus 로고    scopus 로고
    • Why randomized controlled clinical trials do not depict accurately long-term outcomes in rheumatoid arthritis: Some explanations and suggestions for future studies
    • PINCUS T, STEIN CM: Why randomized controlled clinical trials do not depict accurately long-term outcomes in rheumatoid arthritis: Some explanations and suggestions for future studies. Clin Exp Rheumatol 1997;15(Suppl. 17): S27-S38.
    • (1997) Clin. Exp. Rheumatol. , vol.15 , Issue.17 SUPPL.
    • Pincus, T.1    Stein, C.M.2
  • 58
    • 33645296475 scopus 로고    scopus 로고
    • Analgesic-antipyretic agents; pharmacotherapy of gout
    • BRUNTON LL. LAZO JS, PARKER KL, Eds.:, New York, McGraw-Hill
    • BURKE A, SMYTH E, FITZGERALD GA: Analgesic-antipyretic agents; pharmacotherapy of gout. In BRUNTON LL. LAZO JS, PARKER KL, (Eds.): Goodman & Gilman's The Pharmacological Basis of Therapeutics. New York, McGraw-Hill, 2006: pp. 671-716.
    • (2006) Goodman & Gilman's the Pharmacological Basis of Therapeutics , pp. 671-716
    • Burke, A.1    Smyth, E.2    Fitzgerald, G.A.3
  • 60
    • 0027462083 scopus 로고
    • The 'side effects' of rheumatoid arthritis: Joint destruction, disability and early mortality
    • PINCUS T, CALLAHAN LF: The 'side effects' of rheumatoid arthritis: Joint destruction, disability and early mortality. Br J Rheumatol 1993;32: (Suppl. 1):28-37.
    • (1993) Br. J. Rheumatol. , vol.32 , Issue.1 SUPPL. , pp. 28-37
    • Pincus, T.1    Callahan, L.F.2
  • 61
    • 33244497852 scopus 로고    scopus 로고
    • Methotrexate and hepatic toxicity in rheumatoid arthritis and psoriatic arthritis
    • TILLING L, TOWNSEND S, DAVID J: Methotrexate and hepatic toxicity in rheumatoid arthritis and psoriatic arthritis. Clin Drug Investig 2006;26:55-62.
    • (2006) Clin. Drug Investig. , vol.26 , pp. 55-62
    • Tilling, L.1    Townsend, S.2    David, J.3
  • 62
    • 60249102216 scopus 로고    scopus 로고
    • Rheumatoid arthritis, alcohol, leflunomide and methotrexate. Can changes to the BSR guidelines for leflunomide and methotrexate on alcohol consumption be justified?
    • RAJAKULENDRAN S, GADSBY K, DEIGHTON C: Rheumatoid arthritis, alcohol, leflunomide and methotrexate. Can changes to the BSR guidelines for leflunomide and methotrexate on alcohol consumption be justified? Musculoskeletal Care 2008;6:233-45.
    • (2008) Musculoskeletal Care , vol.6 , pp. 233-245
    • Rajakulendran, S.1    Gadsby, K.2    Deighton, C.3
  • 63
    • 33847008303 scopus 로고    scopus 로고
    • Genetics of alcoholic liver disease and nonalcoholic fatty liver disease
    • WILFRED DE ALVVIS NM, DAY CP: Genetics of alcoholic liver disease and nonalcoholic fatty liver disease. Semin Liver Dis 2007;27:044-54.
    • (2007) Semin. Liver Dis. , vol.27 , pp. 044-054
    • Wilfred De Alvvis, N.M.1    Day, C.P.2
  • 64
    • 45349090538 scopus 로고    scopus 로고
    • American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis
    • SAAG KG, TENG GG, PATKAR NM et al.: American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis. Arthritis Rheum 2008;59:762-84.
    • (2008) Arthritis Rheum. , vol.59 , pp. 762-784
    • Saag, K.G.1    Teng, G.G.2    Patkar, N.M.3
  • 65
    • 0033596065 scopus 로고    scopus 로고
    • Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate
    • STRAND V, COHEN S, SCHIFF M et al.: Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Arch Intern Med 1999;159:2542-50.
    • (1999) Arch. Intern. Med. , vol.159 , pp. 2542-2550
    • Strand, V.1    Cohen, S.2    Schiff, M.3
  • 66
    • 9244247260 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxychloroquine, or a combination of all three medications
    • O'DELL JR, HAIRE CE, ERIKSON N et al.: Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxychloroquine, or a combination of all three medications. N Engl J Med 1996;334:1287-91.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1287-1291
    • O'Dell, J.R.1    Haire, C.E.2    Erikson, N.3
  • 67
    • 0034735827 scopus 로고    scopus 로고
    • A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis
    • BATHON JM, MARTIN RW, FLEISCHMANN RM et al.: A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis. N Engl J Med 2000;343:1586-93.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1586-1593
    • Bathon, J.M.1    Martin, R.W.2    Fleischmann, R.M.3
  • 68
    • 0029022389 scopus 로고
    • Combination therapy with cyclosporine and methotrexate in severe rheumatoid arthritis
    • TUGWELL P, PINCUS T, YOCUM D et al.: Combination therapy with cyclosporine and methotrexate in severe rheumatoid arthritis. N Engl J Med 1995;333:137-41.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 137-141
    • Tugwell, P.1    Pincus, T.2    Yocum, D.3
  • 69
    • 0033524159 scopus 로고    scopus 로고
    • Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: A randomized phase III trial
    • MAINI R, ST CLAIR EW, BREEDVELD F et al.: Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: A randomized phase III trial. Lancet 1999;354:1932-9.
    • (1999) Lancet , vol.354 , pp. 1932-1939
    • Maini, R.1    St. Clair, E.W.2    Breedveld, F.3
  • 70
    • 0036190776 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: Results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial
    • COHEN S, HURD E, CUSH J et al.: Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2002;46:614-24.
    • (2002) Arthritis Rheum. , vol.46 , pp. 614-624
    • Cohen, S.1    Hurd, E.2    Cush, J.3
  • 71
    • 0030751946 scopus 로고    scopus 로고
    • Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis
    • BOERS M, VERHOEVEN AC, MARKUSSE HM et al.: Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis. Lancet 1997;350:309-18.
    • (1997) Lancet , vol.350 , pp. 309-318
    • Boers, M.1    Verhoeven, A.C.2    Markusse, H.M.3
  • 72
    • 0033535754 scopus 로고    scopus 로고
    • Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: A randomised trial. FIN-RACo trial group
    • MÖTTÖNEN T, HANNONEN P, LEIRISALOREPO M et al.: Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: A randomised trial. FIN-RACo trial group. Lancet 1999;353:1568-73.
    • (1999) Lancet , vol.353 , pp. 1568-1573
    • Möttönen, T.1    Hannonen, P.2    Leirisalorepo, M.3
  • 73
    • 0025265635 scopus 로고
    • Low-dose cyclosporin versus placebo in patients with rheumatoid arthritis
    • TUGWELL P, BOMBARDIER C, GENT M et al.: Low-dose cyclosporin versus placebo in patients with rheumatoid arthritis. Lancet 1990;335:1051-5.
    • (1990) Lancet , vol.335 , pp. 1051-1055
    • Tugwell, P.1    Bombardier, C.2    Gent, M.3
  • 75
    • 0031851205 scopus 로고    scopus 로고
    • Progression of joint damage in early active severe rheumatoid arthritis during 18 months of treatment: Comparison of lowdose cyclosporin and parenteral gold
    • ZEIDLER HK, KVIEN TK, HANNONEN P et al.: Progression of joint damage in early active severe rheumatoid arthritis during 18 months of treatment: Comparison of lowdose cyclosporin and parenteral gold. Br J Rheumatol 1998;37:874-82.
    • (1998) Br. J. Rheumatol. , vol.37 , pp. 874-882
    • Zeidler, H.K.1    Kvien, T.K.2    Hannonen, P.3
  • 76
    • 6744240506 scopus 로고    scopus 로고
    • Microemulsion formulation of cyclosporin (Sandimmun Neoral) vs Sandimmun: Comparative safety, tolerability and efficacy in severe active rheumatoid arthritis
    • YOCUM D, ALLARD S, COHEN SB et al.: Microemulsion formulation of cyclosporin (Sandimmun Neoral) vs Sandimmun: comparative safety, tolerability and efficacy in severe active rheumatoid arthritis. Rheum 2000;39:156-64.
    • (2000) Rheum. , vol.39 , pp. 156-164
    • Yocum, D.1    Allard, S.2    Cohen, S.B.3
  • 77
    • 0033509841 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and efficacy of combination treatment with methotrexate and leflunomide in patients with active rheumatoid arthritis
    • WEINBLATT ME, KREMER JM, COBLYN JS et al.: Pharmacokinetics, safety, and efficacy of combination treatment with methotrexate and leflunomide in patients with active rheumatoid arthritis. Arthritis Rheum 1999;42:1322-8.
    • (1999) Arthritis Rheum. , vol.42 , pp. 1322-1328
    • Weinblatt, M.E.1    Kremer, J.M.2    Coblyn, J.S.3
  • 78
    • 0033053835 scopus 로고    scopus 로고
    • Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: A double-blind, randomised, multicentre trial
    • SMOLEN JS, KALDEN JR, SCOTT DL et al.: Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: A double-blind, randomised, multicentre trial. Lancet 1999;353:259-66.
    • (1999) Lancet , vol.353 , pp. 259-266
    • Smolen, J.S.1    Kalden, J.R.2    Scott, D.L.3
  • 79
    • 0033495154 scopus 로고    scopus 로고
    • Function and health-related quality of life: Results from a randomized controlled trial of leflunomide versus methotrexate or placebo in patients with active rheumatoid arthritis
    • STRAND V, TUGWELL P, BOMBARDIER C et al.: Function and health-related quality of life: Results from a randomized controlled trial of leflunomide versus methotrexate or placebo in patients with active rheumatoid arthritis. Arthritis Rheum 1999;42:1870-8.
    • (1999) Arthritis Rheum. , vol.42 , pp. 1870-1878
    • Strand, V.1    Tugwell, P.2    Bombardier, C.3
  • 80
    • 0027670271 scopus 로고
    • Effects of oral administration of type II collagen on rheumatoid arthritis
    • TRENTHAM DE, DYNESIUS-TRENTHAM RA, ORAV EJ et al.: Effects of oral administration of type II collagen on rheumatoid arthritis. Science 1993;261:1727-30.
    • (1993) Science , vol.261 , pp. 1727-1730
    • Trentham, D.E.1    Dynesius-Trentham, R.A.2    Orav, E.J.3
  • 81
    • 0033746843 scopus 로고    scopus 로고
    • Immunoadsorption for the treatment of rheumatoid arthritis: Final results of a randomized trial
    • FURST D, FELSON D, THOREN G, GENDREAU RM: Immunoadsorption for the treatment of rheumatoid arthritis: final results of a randomized trial. Therapeutic Apheresis 2000;4:363-73.
    • (2000) Therapeutic Apheresis , vol.4 , pp. 363-373
    • Furst, D.1    Felson, D.2    Thoren, G.3    Gendreau, R.M.4
  • 82
    • 0027298402 scopus 로고
    • Early clinical studies of IL-2 fusion toxin in patients with severe rheumatoid arthritis and recent onset insulin-dependent diabetes mellitus
    • WOODWORTH TG: Early clinical studies of IL-2 fusion toxin in patients with severe rheumatoid arthritis and recent onset insulin-dependent diabetes mellitus. Clin Exp Rheumatol 1993;11(Suppl. 8): S177-S180.
    • (1993) Clin. Exp. Rheumatol. , vol.11 , Issue.8 SUPPL.
    • Woodworth, T.G.1
  • 83
    • 0031760745 scopus 로고    scopus 로고
    • A randomized, blinded, placebo-controlled, dose escalation study of the tolerability and efficacy of filgrastim for haemopoietic stem cell mobilisation in patients with severe active rheumatoid arthritis
    • SNOWDEN JA, BIGGS JC, MILLIKEN ST et al.: A randomized, blinded, placebo-controlled, dose escalation study of the tolerability and efficacy of filgrastim for haemopoietic stem cell mobilisation in patients with severe active rheumatoid arthritis. Bone Marrow Transplant 1998;22:1035-41.
    • (1998) Bone Marrow Transplant. , vol.22 , pp. 1035-1041
    • Snowden, J.A.1    Biggs, J.C.2    Milliken, S.T.3
  • 84
    • 0031660364 scopus 로고    scopus 로고
    • Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis
    • MAINI RN, BREEDVELD FC, KALDEN JR et al.: Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum 1998;41:1552-63.
    • (1998) Arthritis Rheum. , vol.41 , pp. 1552-1563
    • Maini, R.N.1    Breedveld, F.C.2    Kalden, J.R.3
  • 85
    • 17444394445 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist
    • BRESNIHAN B. ALVARO-GRACIA JM, COBBY M et al.: Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis Rheum 1998;41:2196-204.
    • (1998) Arthritis Rheum. , vol.41 , pp. 2196-2204
    • Bresnihan, B.1    Alvaro-Gracia, J.M.2    Cobby, M.3
  • 86
    • 0033611472 scopus 로고    scopus 로고
    • A trial of etanercept, a recombinant tumor necrosis factor receptor: Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate
    • WEINBLATT ME, KREMER JM, BANKHURST AD et al.: A trial of etanercept, a recombinant tumor necrosis factor receptor: Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 1999;340:253-9.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 253-259
    • Weinblatt, M.E.1    Kremer, J.M.2    Bankhurst, A.D.3
  • 87
    • 0038724287 scopus 로고    scopus 로고
    • Most patients receiving routine care for rheumatoid arthritis in 2001 did not meet inclusion criteria for most recent clinical trials or American college of rheumatology criteria for remission
    • SOKKA T, PINCUS T: Most patients receiving routine care for rheumatoid arthritis in 2001 did not meet inclusion criteria for most recent clinical trials or American College of Rheumatology criteria for remission. J Rheumatol 2003;30:1138-46.
    • (2003) J. Rheumatol. , vol.30 , pp. 1138-1146
    • Sokka, T.1    Pincus, T.2
  • 88
    • 0037331259 scopus 로고    scopus 로고
    • Eligibility of patients in routine care for major clinical trials of anti-tumor necrosis factor alpha agents in rheumatoid arthritis
    • SOKKA T, PINCUS T: Eligibility of patients in routine care for major clinical trials of anti-tumor necrosis factor alpha agents in rheumatoid arthritis. Arthritis Rheum 2003;48:313-8.
    • (2003) Arthritis Rheum. , vol.48 , pp. 313-318
    • Sokka, T.1    Pincus, T.2
  • 89
    • 0036274944 scopus 로고    scopus 로고
    • Etanercept versus methotrexate in patients with early rheumatoid arthritis: Twoyear radiographic and clinical outcomes
    • GENOVESE MC, BATHON JM, MARTIN RW et al.: Etanercept versus methotrexate in patients with early rheumatoid arthritis: twoyear radiographic and clinical outcomes. Arthritis Rheum 2002;46:1443-50.
    • (2002) Arthritis Rheum. , vol.46 , pp. 1443-1450
    • Genovese, M.C.1    Bathon, J.M.2    Martin, R.W.3
  • 90
    • 0034735842 scopus 로고    scopus 로고
    • Infliximab and methotrexate in the treatment of rheumatoid arthritis
    • LIPSKY PE, VAN DER HEIJDE D M F M, ST CLAIR EW et al.: Infliximab and methotrexate in the treatment of rheumatoid arthritis. N Engl J Med 2000;343:1594-602.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1594-1602
    • Lipsky, P.E.1    Van Der Heijde, D.M.F.M.2    St. Clair, E.W.3
  • 91
    • 0348111226 scopus 로고    scopus 로고
    • Eligibility of rheumatoid arthritis patients seen in clinical practice for rheumatoid arthritis clinical trials: Comment on the article by Sokka and Pincus
    • YAZICI Y, ERKAN D: Eligibility of rheumatoid arthritis patients seen in clinical practice for rheumatoid arthritis clinical trials: comment on the article by Sokka and Pincus. Arthritis Rheum 2003;48:3611.
    • (2003) Arthritis Rheum. , vol.48 , pp. 3611
    • Yazici, Y.1    Erkan, D.2
  • 92
    • 24944462912 scopus 로고    scopus 로고
    • Inclusion criteria as widely used for rheumatoid arthritis clinical trials: Patient eligibility in a Turkish cohort
    • GOGUS F, YAZICI Y, YAZICI H: Inclusion criteria as widely used for rheumatoid arthritis clinical trials: patient eligibility in a Turkish cohort. Clin Exp Rheumatol 2005;23:681-4.
    • (2005) Clin. Exp. Rheumatol. , vol.23 , pp. 681-684
    • Gogus, F.1    Yazici, Y.2    Yazici, H.3
  • 93
    • 0028024657 scopus 로고
    • The clinical and research significance of the erythrocyte sedimentation rate
    • WOLFE F, MICHAUD K: The clinical and research significance of the erythrocyte sedimentation rate. J Rheumatol 1994;21:1227-37.
    • (1994) J. Rheumatol. , vol.21 , pp. 1227-1237
    • Wolfe, F.1    Michaud, K.2
  • 94
    • 67650466968 scopus 로고    scopus 로고
    • Erythrocyte sedimentation rate, C-reactive protein, or rheumatoid factor are normal at presentation in 35%-45% of patients with rheumatoid arthritis seen between 1980 and 2004: Analyses from Finland and the United States
    • SOKKA T, PINCUS T: Erythrocyte sedimentation rate, C-reactive protein, or rheumatoid factor are normal at presentation in 35%-45% of patients with rheumatoid arthritis seen between 1980 and 2004: analyses from Finland and the United States. J Rheumatol 2009;36:1387-90.
    • (2009) J. Rheumatol. , vol.36 , pp. 1387-1390
    • Sokka, T.1    Pincus, T.2
  • 95
    • 0034770160 scopus 로고    scopus 로고
    • "Stepping-up" from methotrexate: A systematic review of randomised placebo controlled trials in patients with rheumatoid arthritis with an incomplete response to methotrexate
    • HOCHBERG MC, TRACY JK, FLORES RH: "Stepping-up" from methotrexate: a systematic review of randomised placebo controlled trials in patients with rheumatoid arthritis with an incomplete response to methotrexate. Ann Rheum Dis 2001;60: III51-III54.
    • (2001) Ann. Rheum. Dis. , vol.60
    • Hochberg, M.C.1    Tracy, J.K.2    Flores, R.H.3
  • 96
    • 0037976830 scopus 로고    scopus 로고
    • Add-on or step-up trials for new drug development in rheumatoid arthritis: A new standard?
    • BOERS M: Add-on or step-up trials for new drug development in rheumatoid arthritis: a new standard? Arthritis Rheum 2003;48:1481-3.
    • (2003) Arthritis Rheum. , vol.48 , pp. 1481-1483
    • Boers, M.1
  • 97
    • 0141427772 scopus 로고    scopus 로고
    • Definition of discontinuation of anti-tumour necrosis factor therapy in rheumatoid arthritis: A preliminary proposal
    • BRAUN J, SIEPER J, VAN DER HD: Definition of discontinuation of anti-tumour necrosis factor therapy in rheumatoid arthritis: a preliminary proposal. Ann Rheum Dis 2003;62:1023-4.
    • (2003) Ann. Rheum. Dis. , vol.62 , pp. 1023-1024
    • Braun, J.1    Sieper, J.2    Van Der, H.D.3
  • 98
    • 70449730889 scopus 로고    scopus 로고
    • Efficacy of prednisone 1-4 mg/day in patients with rheumatoid arthritis: A randomised, double-blind, placebo controlled withdrawal clinical trial
    • PINCUS T, SWEARINGEN CJ, LUTA G, SOKKA T: Efficacy of prednisone 1-4 mg/day in patients with rheumatoid arthritis: a randomised, double-blind, placebo controlled withdrawal clinical trial. Ann Rheum Dis 2009;68:1715-20.
    • (2009) Ann. Rheum. Dis. , vol.68 , pp. 1715-1720
    • Pincus, T.1    Swearingen, C.J.2    Luta, G.3    Sokka, T.4
  • 99
    • 10744223002 scopus 로고    scopus 로고
    • Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: Double-blind randomised controlled trial
    • KLARESKOG L, VAN DER HEIJDE D, DE JAGER JP et al.: Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial. Lancet 2004;363:675-81.
    • (2004) Lancet , vol.363 , pp. 675-681
    • Klareskog, L.1    Van Der Heijde, D.2    De Jager, J.P.3
  • 100
    • 0037231533 scopus 로고    scopus 로고
    • Adalimumab, a fully human anti-tumor necrosis factor a monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: The ARMADA trial
    • WEINBLATT ME, KEYSTONE EC, FURST DE et al.: Adalimumab, a fully human anti-tumor necrosis factor a monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial. Arthritis Rheum 2003;48:35-45.
    • (2003) Arthritis Rheum. , vol.48 , pp. 35-45
    • Weinblatt, M.E.1    Keystone, E.C.2    Furst, D.E.3
  • 101
    • 33745291091 scopus 로고    scopus 로고
    • Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: A randomized trial
    • KREMER JM, GENANT HK, MORELAND LW et al.: Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: a randomized trial. Ann Intern Med 2006;144:865-76.
    • (2006) Ann. Intern. Med. , vol.144 , pp. 865-876
    • Kremer, J.M.1    Genant, H.K.2    Moreland, L.W.3
  • 102
    • 33646483031 scopus 로고    scopus 로고
    • The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: Results of a phase IIB randomized, doubleblind, placebo-controlled, dose-ranging trial
    • EMERY P, FLEISCHMANN R, FILIPOWICZ-SOSNOWSKA A etal: The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, doubleblind, placebo-controlled, dose-ranging trial. Arthritis Rheum 2006;54:1390-400.
    • (2006) Arthritis Rheum. , vol.54 , pp. 1390-1400
    • Emery, P.1    Fleischmann, R.2    Filipowicz-Sosnowska, A.3    Etal4
  • 103
    • 55849112632 scopus 로고    scopus 로고
    • Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: Findings of a fifty-two-week, phase III, multicenter, randomized, doubleblind, placebo-controlled, parallel-group study
    • KEYSTONE E, VAN DER HEIJDE D, MASON D, JR. et al.: Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: findings of a fifty-two-week, phase III, multicenter, randomized, doubleblind, placebo-controlled, parallel-group study. Arthritis Rheum 2008;58:3319-29.
    • (2008) Arthritis Rheum. , vol.58 , pp. 3319-3329
    • Keystone, E.1    Van Der Heijde, D.2    Mason Jr., D.3
  • 104
    • 42449157502 scopus 로고    scopus 로고
    • Golimumab in patients with active rheumatoid arthritis despite treatment with methotrexate: A randomized, double-blind, placebo-controlled, dose-ranging study
    • KAY J, MATTESON EL, DASGUPTA B et al.: Golimumab in patients with active rheumatoid arthritis despite treatment with methotrexate: a randomized, double-blind, placebo-controlled, dose-ranging study. Arthritis Rheum 2008;58:964-75.
    • (2008) Arthritis Rheum. , vol.58 , pp. 964-975
    • Kay, J.1    Matteson, E.L.2    Dasgupta, B.3
  • 105
    • 33749363027 scopus 로고    scopus 로고
    • Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate
    • MAINI RN, TAYLOR PC, SZECHINSKI J et al.: Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate. Arthritis Rheum 2006;54:2817-29.
    • (2006) Arthritis Rheum. , vol.54 , pp. 2817-2829
    • Maini, R.N.1    Taylor, P.C.2    Szechinski, J.3
  • 108
    • 48949117149 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha inhibitors, methotrexate or both? An inquiry into the formal evidence for when they are to be used in rheumatoid arthritis
    • YAZICI Y, YAZICI H: Tumor necrosis factor alpha inhibitors, methotrexate or both? An inquiry into the formal evidence for when they are to be used in rheumatoid arthritis. Clin Exp Rheumatol 2008;26:449-52.
    • (2008) Clin. Exp. Rheumatol. , vol.26 , pp. 449-452
    • Yazici, Y.1    Yazici, H.2
  • 109
    • 70949107545 scopus 로고    scopus 로고
    • Radiographic measures to assess patients with rheumatoid arthritis: Advantages and limitations
    • YAZICI Y, SOKKA T, PINCUS T: Radiographic measures to assess patients with rheumatoid arthritis: advantages and limitations. Rheum Dis Clin North Am 2009;35:723-9.
    • (2009) Rheum. Dis. Clin. North Am. , vol.35 , pp. 723-729
    • Yazici, Y.1    Sokka, T.2    Pincus, T.3
  • 110
    • 0036905477 scopus 로고    scopus 로고
    • Evidence from clinical trials and long-term observational studies that disease-modifying anti-rheumatic drugs slow radiographic progression in rheumatoid arthritis: Updating a 1983 review
    • PINCUS T, FERRACCIOLI G, SOKKA T et al.: Evidence from clinical trials and long-term observational studies that disease-modifying anti-rheumatic drugs slow radiographic progression in rheumatoid arthritis: updating a 1983 review. Rheumatology 2002;41:1346-56.
    • (2002) Rheumatology , vol.41 , pp. 1346-1356
    • Pincus, T.1    Ferraccioli, G.2    Sokka, T.3
  • 111
    • 1542283763 scopus 로고    scopus 로고
    • Radiographic progression depicted by probability plots: Presenting data with optimal use of individual values
    • LANDEWÉ R, VAN DER HEUDE D: Radiographic progression depicted by probability plots: presenting data with optimal use of individual values. Arthritis Rheum 2004;50:699-706.
    • (2004) Arthritis Rheum. , vol.50 , pp. 699-706
    • Landewé, R.1    Van Der Heude, D.2
  • 112
    • 55349118821 scopus 로고    scopus 로고
    • Mortality in rheumatoid arthritis: 2008 update
    • SOKKA T, ABELSON B, PINCUS T: Mortality in rheumatoid arthritis: 2008 update. Clin Exp Rheumatol 2008;26(Suppl. 51): S35-S61.
    • (2008) Clin. Exp. Rheumatol. , vol.26 , Issue.51 SUPPL.
    • Sokka, T.1    Abelson, B.2    Pincus, T.3
  • 113
    • 8444239359 scopus 로고    scopus 로고
    • Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: A randomized, controlled trial
    • ST. CLAIR EW, VAN DER HEIJDE DM, SMOLEN JS et al.: Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial. Arthritis Rheum 2004;50:3432-43.
    • (2004) Arthritis Rheum. , vol.50 , pp. 3432-3443
    • St. Clair, E.W.1    Van Der Heijde, D.M.2    Smolen, J.S.3
  • 114
    • 31044442965 scopus 로고    scopus 로고
    • The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment
    • BREEDVELD FC, WEISMAN MH, KAVANAUGH AF et al.: The PREMIER study: a multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment. Arthritis Rheum 2006;54:26-37.
    • (2006) Arthritis Rheum. , vol.54 , pp. 26-37
    • Breedveld, F.C.1    Weisman, M.H.2    Kavanaugh, A.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.