Adjuvant metformin worsens psychosis in schizophrenia: A case report

Primary Care Companion to the Journal of Clinical Psychiatry

Volumn 12, Issue 2, 2010, Pages

  Venkatasubramanian, Ganesan ^a   Arasappa, Rashmi ^a   Rao, Naren P ^a   Behere, Rishikesh V ^a   Gangadhar, Bangalore N ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

METFORMIN; RISPERIDONE; TRIHEXYPHENIDYL;

ACNE; ADD ON THERAPY; ADJUVANT THERAPY; ADULT; CASE REPORT; DISEASE EXACERBATION; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG WITHDRAWAL; ECHOGRAPHY; EXERCISE; FEMALE; FOLLOW UP; HIRSUTISM; HUMAN; LETTER; MENSTRUATION DISORDER; OVARY POLYCYSTIC DISEASE; PROLACTIN BLOOD LEVEL; PSYCHOSIS; SCHIZOPHRENIA; SIDE EFFECT; THOUGHT BROADCAST; WEIGHT GAIN;

EID: 78650567492     PISSN: 15235998     EISSN: 1555211X     Source Type: Journal    
DOI: 10.4088/PCC.09l00801yel     Document Type: Letter

References (5)

1. Wu RR, Zhao JP, Jin H, et al. Lifestyle intervention and metformin for treatment of antipsychotic-induced weight gain: a randomized controlled trial. JAMA. 2008;299(2):185-193. doi:10.1001/jama.2007.56-b PubMed
2. Fruehwald-Schultes B, Oltmanns KM, Toschek B, et al. Short-term treatment with metformin decreases serum leptin concentration without affecting body weight and body fat content in normal-weight healthy men. Metabolism. 2002;51(4):531-536. doi:10.1053/meta.2002.31332 PubMed
3. Gunnell D, Holly JM. Hypothesis: do insulin-like growth factors underlie associations of birth complications, fetal and pre-adult growth with schizophrenia? Schizophr Res. 2004;71(1):191-193. doi:10.1016/S0920-9964(03)00224-X PubMed
4. Venkatasubramanian G, Chittiprol S, Neelakantachar N, et al. Insulin and insulin-like growth factor-1 abnormalities in antipsychotic-naive schizophrenia. Am J Psychiatry. 2007;164(10):1557-1560. doi:10.1176/appi.ajp.2007.07020233 PubMed
5. Venkatasubramanian G. Antipsychotic-induced weight gain in patients with schizophrenia. JAMA. 2008;299(16):1899-1900. doi:10.1001/jama.299.16.1899-a PubMed