Peripheral blood memory B cells are resistant to apoptosis in chronic hepatitis C patients

Virus Research

Volumn 155, Issue 1, 2011, Pages 349-351

  Mizuochi, Toshiaki ^a   Ito, Masahiko ^a   Takai, Kenji ^b   Yamaguchi, Kazunari ^a  

^a Department of Research on Blood and Biological Products ^*  (Japan)

^b SRL INC   (Japan)

Author keywords

Apoptosis; HCV; Memory B cell

Indexed keywords

CD27 ANTIGEN;

ADULT; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEPATITIS C; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; INFECTION SENSITIVITY; MALE; MEMORY CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL;

AGED; ANTIGENS, CD27; APOPTOSIS; B-LYMPHOCYTES; FEMALE; HEPATITIS C, CHRONIC; HUMANS; IMMUNOLOGIC MEMORY; MALE; MIDDLE AGED;

HEPATITIS C VIRUS;

EID: 78650566274     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2010.09.017     Document Type: Article

References (9)

1. Agematsu K., Hokibara S., Nagumo H., Komiyama A. CD27: a memory B-cell marker. Immunol. Today 2000, 21(5):204-206.
2. Agnello V., Chung R.T., Kaplan L.M. A role for hepatitis C virus infection in type II cryoglobulinemia. N. Engl. J. Med. 1992, 327(21):1490-1495.
3. Inokuchi M., Ito T., Uchikoshi M., Shimozuma Y., Morikawa K., Nozawa H., Shimazaki T., Hiroishi K., Miyakawa Y., Imawari M. Infection of B cells with hepatitis C virus for the development of lymphoproliferative disorders in patients with chronic hepatitis C. J. Med. Virol. 2009, 81(4):619-627.
4. Ito M., Murakami K., Suzuki T., Mochida K., Suzuki M., Ikebuchi K., Yamaguchi K., Mizuochi T. Enhanced expression of lymphomagenesis-related genes in peripheral blood B cells of chronic hepatitis C patients. Clin. Immunol. 2010, 135(3):459-465.
5. Lauer G.M., Walker B.D. Hepatitis C virus infection. N. Engl. J. Med. 2001, 345(1):41-52.
6. Mizuochi T., Ito M., Saito K., Kasai M., Kunimura T., Morohoshi T., Momose H., Hamaguchi I., Takai K., Iino S., Suzuki M., Mochida S., Ikebuchi K., Yamaguchi K. Possible recruitment of peripheral blood CXCR3+ CD27+ CD19+ B cells to the liver of chronic hepatitis C patients. J. Interferon Cytokine Res. 2010, 30(4):243-252.
7. Ohno O., Mizokami M., Wu R.R., Saleh M.G., Ohba K., Orito E., Mukaide M., Williams R., Lau J.Y. New hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a. J. Clin. Microbiol. 1997, 35(1):201-207.
8. Racanelli V., Frassanito M.A., Leone P., Galiano M., De Re V., Silvestris F., Dammacco F. Antibody production and in vitro behavior of CD27-defined B-cell subsets: persistent hepatitis C virus infection changes the rules. J. Virol. 2006, 80(8):3923-3934.
9. Zuckerman E., Zuckerman T., Levine A.M., Douer D., Gutekunst K., Mizokami M., Qian D.G., Velankar M., Nathwani B.N., Fong T.L. Hepatitis C virus infection in patients with B-cell non-Hodgkin lymphoma. Ann. Intern. Med. 1997, 127(6):423-428.