Optimization of productivity in solvent gradient simulated moving bed for paclitaxel purification

Process Biochemistry

Volumn 43, Issue 12, 2008, Pages 1407-1418

  Mun, Sungyong ^a   Wang, Nien Hwa Linda ^b  

^a Hanyang University   (South Korea)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Model simulation; Optimization; Paclitaxel purification; Productivity; Simulated moving bed; Wave dynamics

Indexed keywords

ADSORPTION; CONCENTRATION (PROCESS); DESORPTION; ETHANOL; FLOW OF GASES; FLOW RATE; GENETIC ALGORITHMS; OPTIMIZATION; PURIFICATION; SOLVENTS;

COLUMN EFFICIENCIES; ETHANOL CONCENTRATIONS; ISOCRATIC; JUMPING GENES; MODEL SIMULATION; NON-DOMINATED SORTING GENETIC ALGORITHMS; NSGA-II; OPTIMAL SOLVENTS; OPTIMIZED USING; PACLITAXEL; PACLITAXEL PURIFICATION; PRODUCT PURITIES; RATE CONSTRAINTS; RATE MODELS; SIMULATED MOVING BED; SIMULATED MOVING BEDS; SOLVENT COMPOSITIONS; SOLVENT CONCENTRATIONS; SOLVENT GRADIENTS; SWITCHING TIMES; TRANSFER EFFICIENCIES; WAVE DYNAMICS;

PRODUCTIVITY;

EID: 54949145293     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2008.08.011     Document Type: Article

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