An HPLC method for the pharmacokinetic study of daidzein-loaded nanoparticle formulations after injection to rats

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 1, 2011, Pages 113-116

  Zhao, Xinyi ^a   Shen, Qi ^a   Ma, Yiran ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Daidzein; HPLC; Nanoparticles; Pharmacokinetics; PLGA

Indexed keywords

CALIBRATION CURVES; CHROMATOGRAPHIC SEPARATIONS; CONCENTRATION RANGES; DAIDZEIN; HPLC; HPLC METHOD; INJECTION VOLUME; INTERNAL STANDARDS; INTRAVENOUS INJECTIONS; METHANOL-WATER; MOBILE PHASE; NANOPARTICLE FORMULATION; PHARMACOKINETIC PARAMETERS; PHARMACOKINETIC STUDIES; PLGA; POLY-LACTIDE-CO-GLYCOLIDE; RAT PLASMA;

METHANOL; NANOPARTICLES; PHARMACOKINETICS; PLASMA (HUMAN); RATS;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

BETA CYCLODEXTRIN; DAIDZEIN; ETHYL PARABEN; GENISTEIN; METHANOL; NANOPARTICLE; POLYGLACTIN; WATER;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CALIBRATION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG IMPURITY; DRUG ISOLATION; DRUG STRUCTURE; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INJECTION; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PRIORITY JOURNAL; RAT; SUSPENSION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DELIVERY SYSTEMS; INJECTIONS, INTRAVENOUS; ISOFLAVONES; LACTIC ACID; LINEAR MODELS; MALE; NANOPARTICLES; POLYGLYCOLIC ACID; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY;

RATTUS;

EID: 78650522700     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.10.036     Document Type: Article

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