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Volumn 879, Issue 1, 2011, Pages 107-112
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Characterization of tyrosine kinase and screening enzyme inhibitor by capillary electrophoresis with laser-induced fluoresce detector
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Author keywords
Capillary electrophoresis; Inhibitor screening; Laser induced fluoresce; The transformation ratio of the substrate; Tyrosine kinase
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Indexed keywords
DETECTION SENSITIVITY;
DRUG SCREENING;
ENZYME INHIBITORS;
ENZYME REACTION;
EXPERIMENTAL CONDITIONS;
INHIBITOR SCREENING;
LASER INDUCED;
LASER INDUCED FLUORESCENCE;
LASER-INDUCED FLUORESCE;
POLYPEPTIDE SUBSTRATES;
REACTION CONDITIONS;
STAUROSPORINES;
TRANSFORMATION RATIO;
TYROSINE KINASE;
AMINO ACIDS;
CAPILLARY ELECTROPHORESIS;
ENZYMES;
FLUORESCENCE;
OPTIMIZATION;
SUBSTRATES;
ELECTROCHEMISTRY;
2,3 DIHYDRO 2 OXO 3 (4,5,6,7 TETRAHYDRO 1H INDOL 2 YLMETHYLENE) 1H INDOLE 5 SULFONIC ACID DIMETHYLAMIDE;
POLYPEPTIDE;
PROTEIN TYROSINE KINASE;
STAUROSPORINE;
ARTICLE;
BIOLOGICAL MONITORING;
BIOTRANSFORMATION;
CAPILLARY ELECTROPHORESIS;
CATALYSIS;
DRUG MECHANISM;
DRUG SCREENING;
ENZYME ACTIVITY;
ENZYME ANALYSIS;
ENZYME INHIBITION;
ENZYME MECHANISM;
ENZYME SUBSTRATE;
FLUORESCENCE ANALYSIS;
INCUBATION TEMPERATURE;
LASER;
PRIORITY JOURNAL;
PROTEIN ANALYSIS;
AMINO ACID SEQUENCE;
DRUG DISCOVERY;
ELECTROPHORESIS, CAPILLARY;
HYDROGEN-ION CONCENTRATION;
INDOLES;
MOLECULAR SEQUENCE DATA;
PROTEIN KINASE INHIBITORS;
PROTEIN-TYROSINE KINASES;
REPRODUCIBILITY OF RESULTS;
SPECTROMETRY, FLUORESCENCE;
STAUROSPORINE;
SULFONAMIDES;
TEMPERATURE;
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EID: 78650520349
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2010.10.034 Document Type: Article |
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Times cited : (23)
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References (26)
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