Synthesis and activity evaluation of a new bestatin derivative LYP2 as an aminopeptidase N inhibitor

Anti-Cancer Drugs

Volumn 22, Issue 1, 2011, Pages 99-103

  Luan, Yepeng ^a   Wang, Qiang ^a   Liu, Ning ^a   Mou, Jiajia ^a   Jiao, Xijuan ^a   Fang, Hao ^a   Li, Minyong ^a   Xu, Wenfang ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

2 dimethylaminoethylamine; A549; aminopeptidase N; bestatin; ES 2; H7402; HL60; K562; PLC

Indexed keywords

BESTATIN; BESTATIN DERIVATIVE; ENZYME INHIBITOR; GELATINASE A; LYP 2; MICROSOMAL AMINOPEPTIDASE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; DRUG EFFICACY; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMIDES; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIGENS, CD13; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; K562 CELLS; LEUCINE; MATRIX METALLOPROTEINASE 2; MICE; MODELS, MOLECULAR; PROTEASE INHIBITORS; SWINE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 78650515832     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/CAD.0b013e32833ab78a     Document Type: Article

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