Discovery of highly potent agents against influenza A virus

European Journal of Medicinal Chemistry

Volumn 46, Issue 1, 2011, Pages 52-57

  Zhao, Xin ^a   Li, Chufang ^a   Zeng, Shaogao ^a   Hu, Wenhui ^a,b  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b State Key Laboratory of Respiratory Disease   (China)

Author keywords

Hit to lead optimization; Influenza A virus; SAR study

Indexed keywords

2 [[(2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 YL)IMINO]METHYL]PHENOL; 2,6,6 TRIMETHYL N (4 METHYLBENZYLIDENE)BICYCLO[3.1.1]HEPTAN 3 AMINE; 3 [[(2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 YL)IMINO]METHYL]PHENOL; 4 [[(2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 YL)AMINO]METHYL]PHENOL; 4 [[(2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 YL)IMINO]METHYL]PHENOL; AMANTADINE; ANTIVIRUS AGENT; N (4 FLUOROBENZYL) 2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 AMINE; N (4 FLUOROBENZYLIDENE) 2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 AMINE; N (CYCLOPROPYLMETHYL) 2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 AMINE; N [4 (DIMETHYLAMINO)BENZYLIDENE] 2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 AMINE; N BENZYLIDENE 2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 AMINE; N CYCLOHEXYL 2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 AMINE; N ETHYL 2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 AMINE; N ISOPROPYL 2,6,6 TRIMETHYLBICYCLO[3.1.1]HEPTAN 3 AMINE; N,2,6,6 TETRAMETHYLBICYCLO[3.1.1]HEPTAN 3 AMINE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; INFLUENZA VIRUS A; INFLUENZA VIRUS A H1N1; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CELL SURVIVAL; DOGS; DRUG DISCOVERY; INFLUENZA A VIRUS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; PLAQUE ASSAY; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL MATRIX PROTEINS;

EID: 78650515603     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.10.010     Document Type: Article

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