Measurement of procoagulant platelet subpopulations in whole blood: Development of an assay for population-based studies

Thrombosis Research

Volumn 127, Issue 1, 2011, Pages 62-64

  Bouchard, Beth A ^a   Paradis, Aimee K ^a   Brummel Ziedins, Kathleen E ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A; CD61 ANTIGEN; CELL MARKER; EDETIC ACID; PADGEM PROTEIN; PROCOAGULANT; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 4; TRYPSIN INHIBITOR;

ADULT; BLOOD; CELL SUBPOPULATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; LETTER; MALE; NORMAL HUMAN; PILOT STUDY; PRIORITY JOURNAL; PROTEIN BINDING; THROMBOCYTE; THROMBOCYTE ACTIVATION;

ADULT; ANALYSIS OF VARIANCE; BLOOD COAGULATION; BLOOD COAGULATION TESTS; BLOOD PLATELETS; FACTOR V; FACTOR XA; FEASIBILITY STUDIES; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; PILOT PROJECTS; PLATELET ACTIVATION; PLATELET FUNCTION TESTS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; THROMBIN; TIME FACTORS; YOUNG ADULT;

EID: 78650515162     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2010.05.014     Document Type: Letter

References (20)

1. M. Hoffman, D.M. Monroe, J.A. Oliver, and H.R. Roberts Factors IXa and Xa play distinct roles in tissue factor-dependent initiation of coagulation Blood 86 1995 1794 1801
2. P.B. Tracy, M.E. Nesheim, and K.G. Mann Platelet factor Xa receptor Meth Enzymol 215 1992 329 360
3. B.A. Bouchard, C.S. Catcher, B.R. Thrash, C. Adida, and P.B. Tracy Effector cell protease receptor-1, a platelet activation-dependent membrane protein, regulates prothrombinase-catalyzed thrombin generation J Biol Chem 272 1997 9244 9251
4. S.S. Ahmad, R. Rawala-Sheikh, and P.N. Walsh Platelet receptor occupancy with factor IXa promotes factor X activation J Biol Chem 264 1989 20012 20016
5. S.S. Ahmad, F.S. London, and P.N. Walsh The assembly of the factor X-activating complex on activated human platelets J Thromb Haemost 1 2003 48 59
6. D.M. Monroe, M. Hoffman, and H.R. Roberts Platelets and thrombin generation Arterioscler Thromb Vasc Biol 22 2002 1381 1389
7. F.S. London, M. Marcinkiewicz, and P.N. Walsh A subpopulation of platelets responds to thrombin- or SFLLRN-stimulation with binding sites for factor IXa J Biol Chem 279 2004 19854 19859
8. C.L. Kempton, M. Hoffman, H.R. Roberts, and D.M. Monroe Platelet heterogeneity: variation in coagulation complexes on platelet subpopulations Arterioscler Thromb Vasc Biol 25 2005 861 866
9. P. Feng, and P.B. Tracy Not all platelets are equal procoagulants? Blood 92 1998 1441a
10. L. Alberio, O. Safa, K.J. Clemetson, C.T. Esmon, and G.L. Dale Surface expression and functional characterization of alpha-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin Blood 95 2000 1694 1702
11. M.A. Panteleev, N.M. Ananyeva, N.J. Greco, F.I. Ataullakhanov, and E.L. Saenko Two subpopulations of thrombin-activated platelets differ in their binding of the components of the intrinsic factor X-activating complex J Thromb Haemost 3 2005 2545 2553
12. G.L. Dale, P. Friese, P. Batar, S.F. Hamilton, G.L. Reed, and K.W. Jackson Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface Nature 415 2002 175 179
13. N.R. Goldsack, R.C. Chambers, K. Dabbagh, and G.J. Laurent Thrombin Int J Biochem Cell Biol 30 1998 641 646
14. R. Shah Protease-activated receptors in cardiovascular health and diseases Am Heart J 157 2009 253 262
15. K.M. Cawthern, van 't. Veer C., J.B. Lock, M.E. DiLorenzo, R.F. Branda, and K.G. Mann Blood coagulation in hemophilia A and hemophilia C Blood 91 1998 4581 4592
16. P.A. Sakkinen, E.M. Macy, P.W. Callas, E.S. Cornell, T.E. Hayes, and L.H. Kuller Analytical and biologic variability in measures of hemostasis, fibrinolysis, and inflammation: assessment and implications for epidemiology Am J Epidemiol 149 1999 261 267
17. M.D. Rand, J.B. Lock, van't Veer C., D.P. Gaffney, and K.G. Mann Blood clotting in minimally altered whole blood Blood 88 1996 3432 3445
18. B.A. Bouchard, A.K. Paradis, G.E. Rivard, and K.E. Brummel-Ziedins Procoagulant platelet subpopulation formation in whole blood: Correlation with whole blood clotting time and 5-year mean bleeding score in individuals with factor VIII deficiency Blood 114 Suppl. 1 2009 4022
19. K.E. Brummel-Ziedins, M.F. Whelihan, M. Gissel, K.G. Mann, and G.E. Rivard Thrombin generation and bleeding in hemophilia A Haemophilia 15 2009 1118 1125
20. E.G. Bovill, J.A. Tomczak, B. Grant, F. Bhushan, E. Pillemer, and I.R. Rainville Protein CVermont: symptomatic type II protein C deficiency associated with two GLA domain mutations Blood 79 1992 1456 1465