메뉴 건너뛰기




Volumn 5, Issue 12, 2010, Pages 1939-1948

Ligands of epidermal growth factor receptor and the insulin-like growth factor family as serum biomarkers for response to epidermal growth factor receptor inhibitors in patients with advanced non-small cell lung cancer

Author keywords

EGFR ligands; EGFR tyrosine kinase inhibitors; Insulin like growth factor; Non small cell lung cancer; Serum biomarkers

Indexed keywords

AMPHIREGULIN; BIOLOGICAL MARKER; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; GEFITINIB; LIGAND; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN 3; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 78650504769     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e3181f77a39     Document Type: Article
Times cited : (27)

References (60)
  • 1
    • 0037109014 scopus 로고    scopus 로고
    • ZD1839 Iressa: An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy
    • Wakeling AE, Guy SP, Woodburn JR, et al. ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res 2002;62:5749-5754.
    • (2002) Cancer Res. , vol.62 , pp. 5749-5754
    • Wakeling, A.E.1    Guy, S.P.2    Woodburn, J.R.3
  • 7
    • 19844375720 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in non-small-cell lung cancer: Implications for treatment and tumor biology
    • DOI 10.1200/JCO.2005.09.985
    • Janne PA, Engelman JA, Johnson BE. Epidermal growth factor receptor mutations in non-small-cell lung cancer: implications for treatment and tumor biology. J Clin Oncol 2005;23:3227-3234. (Pubitemid 46211347)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.14 , pp. 3227-3234
    • Janne, P.A.1    Engelman, J.A.2    Johnson, B.E.3
  • 11
    • 33846483745 scopus 로고    scopus 로고
    • EGFR and KRAS mutations as criteria for treatment with tyrosine kinase inhibitors: Retro- and prospective observations in non-small-cell lung cancer
    • DOI 10.1093/annonc/mdl323
    • van Zandwijk N, Mathy A, Boerrigter L, et al. EGFR and KRAS mutations as criteria for treatment with tyrosine kinase inhibitors: retro- and prospective observations in non-small-cell lung cancer. Ann Oncol 2007;18:99-103. (Pubitemid 46152507)
    • (2007) Annals of Oncology , vol.18 , Issue.1 , pp. 99-103
    • Van Zandwijk, N.1    Mathy, A.2    Boerrigter, L.3    Ruijter, H.4    Tielen, I.5    De Jong, D.6    Baas, P.7    Burgers, S.8    Nederlof, P.9
  • 12
    • 38649094549 scopus 로고    scopus 로고
    • Disease control rate at 8 weeks predicts clinical benefit in advanced non-small-cell lung cancer: Results from Southwest Oncology Group randomized trials
    • DOI 10.1200/JCO.2007.13.0344
    • Lara PN Jr, Redman MW, Kelly K, et al. Disease control rate at 8 weeks predicts clinical benefit in advanced non-small-cell lung cancer: results from Southwest Oncology Group randomized trials. J Clin Oncol 2008; 26:463-467. (Pubitemid 351171700)
    • (2008) Journal of Clinical Oncology , vol.26 , Issue.3 , pp. 463-467
    • Lara Jr., P.N.1    Redman, M.W.2    Kelly, K.3    Edelman, M.J.4    Williamson, S.K.5    Crowley, J.J.6    Gandara, D.R.7
  • 13
    • 19944426858 scopus 로고    scopus 로고
    • High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan
    • Huang SF, Liu HP, Li LH, et al. High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan. Clin Cancer Res 2004;10:8195-8203.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 8195-8203
    • Huang, S.F.1    Liu, H.P.2    Li, L.H.3
  • 19
    • 33645748963 scopus 로고    scopus 로고
    • Transforming growth factor alpha expression drives constitutive epidermal growth factor receptor pathway activation and sensitivity to gefitinib Iressa in human pancreatic cancer cell lines
    • Pino MS, Shrader M, Baker CH, et al. Transforming growth factor alpha expression drives constitutive epidermal growth factor receptor pathway activation and sensitivity to gefitinib (Iressa) in human pancreatic cancer cell lines. Cancer Res 2006;66:3802-3812.
    • (2006) Cancer Res. , vol.66 , pp. 3802-3812
    • Pino, M.S.1    Shrader, M.2    Baker, C.H.3
  • 20
    • 33947727520 scopus 로고    scopus 로고
    • Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib
    • DOI 10.1016/j.yexcr.2007.01.016, PII S0014482707000493
    • Liu X, Carlisle DL, Swick MC, et al. Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib. Exp Cell Res 2007;313:1361-1372. (Pubitemid 46507449)
    • (2007) Experimental Cell Research , vol.313 , Issue.7 , pp. 1361-1372
    • Liu, X.1    Carlisle, D.L.2    Swick, M.C.3    Gaither-Davis, A.4    Grandis, J.R.5    Siegfried, J.M.6
  • 21
    • 55449123441 scopus 로고    scopus 로고
    • Clinical significance of pretreatment serum amphiregulin and transforming growth factor-alpha and an epidermal growth factor receptor somatic mutation in patients with advanced non-squamous non-small cell lung cancer
    • Masago K, Fujita S, Hatachi Y, et al. Clinical significance of pretreatment serum amphiregulin and transforming growth factor-alpha, and an epidermal growth factor receptor somatic mutation in patients with advanced non-squamous, non-small cell lung cancer. Cancer Sci 2008; 99:2295-2301.
    • (2008) Cancer Sci. , vol.99 , pp. 2295-2301
    • Masago, K.1    Fujita, S.2    Hatachi, Y.3
  • 22
    • 0036141447 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling
    • Chakravarti A, Loeffler JS, Dyson NJ. Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. Cancer Res 2002;62:200-207. (Pubitemid 34074005)
    • (2002) Cancer Research , vol.62 , Issue.1 , pp. 200-207
    • Chakravarti, A.1    Loeffler, J.S.2    Dyson, N.J.3
  • 24
    • 54249117292 scopus 로고    scopus 로고
    • Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors
    • Buck E, Eyzaguirre A, Rosenfeld-Franklin M, et al. Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors. Cancer Res 2008;68:8322-8332.
    • (2008) Cancer Res. , vol.68 , pp. 8322-8332
    • Buck, E.1    Eyzaguirre, A.2    Rosenfeld-Franklin, M.3
  • 26
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 1995;16:3-34.
    • (1995) Endocr. Rev. , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 27
    • 0034692430 scopus 로고    scopus 로고
    • Role of the insulin-like growth factor family in cancer development and progression
    • Yu H, Rohan T. Role of the insulin-like growth factor family in cancer development and progression. J Natl Cancer Inst 2000;92:1472-1489.
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1472-1489
    • Yu, H.1    Rohan, T.2
  • 28
    • 0036905115 scopus 로고    scopus 로고
    • Cellular actions of the insulin-like growth factor binding proteins
    • DOI 10.1210/er.2001-0033
    • Firth SM, Baxter RC. Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev 2002;23:824-854. (Pubitemid 35454590)
    • (2002) Endocrine Reviews , vol.23 , Issue.6 , pp. 824-854
    • Firth, S.M.1    Baxter, R.C.2
  • 29
    • 23244462857 scopus 로고    scopus 로고
    • Insulin-like growth factor-I and insulin are associated with the presence and advancement of adenomatous polyps
    • Schoen RE, Weissfeld JL, Kuller LH, et al. Insulin-like growth factor-I and insulin are associated with the presence and advancement of adenomatous polyps. Gastroenterology 2005;129:464-475.
    • (2005) Gastroenterology , vol.129 , pp. 464-475
    • Schoen, R.E.1    Weissfeld, J.L.2    Kuller, L.H.3
  • 30
    • 33645499828 scopus 로고    scopus 로고
    • The insulin-like growth factor system and mammographic features in premenopausal and postmenopausal women
    • dos Santos Silva I, Johnson N, De Stavola B, et al. The insulin-like growth factor system and mammographic features in premenopausal and postmenopausal women. Cancer Epidemiol Biomarkers Prev 2006;15:449-455.
    • (2006) Cancer Epidemiol. Biomarkers Prev. , vol.15 , pp. 449-455
    • Dos Santos Silva, I.1    Johnson, N.2    De Stavola, B.3
  • 31
    • 67349092910 scopus 로고    scopus 로고
    • Number of aberrant crypt foci associated with adiposity and IGF1 bioavailability
    • Swede H, Rohan TE, Yu H, et al. Number of aberrant crypt foci associated with adiposity and IGF1 bioavailability. Cancer Causes Control 2009;20:653-661.
    • (2009) Cancer Causes Control. , vol.20 , pp. 653-661
    • Swede, H.1    Rohan, T.E.2    Yu, H.3
  • 33
    • 35348887755 scopus 로고    scopus 로고
    • A SAS macro for estimation of direct adjusted survival curves based on a stratified Cox regression model
    • DOI 10.1016/j.cmpb.2007.07.010, PII S0169260707001861
    • Zhang X, Loberiza FR, Klein JP, et al. A SAS macro for estimation of direct adjusted survival curves based on a stratified Cox regression model. Comput Methods Programs Biomed 2007;88:95-101. (Pubitemid 47588441)
    • (2007) Computer Methods and Programs in Biomedicine , vol.88 , Issue.2 , pp. 95-101
    • Zhang, X.1    Loberiza, F.R.2    Klein, J.P.3    Zhang, M.-J.4
  • 34
    • 66749121947 scopus 로고    scopus 로고
    • Determinants of response to epidermal growth factor receptor tyrosine kinase inhibition in squamous cell carcinoma of the head and neck
    • Rogers SJ, Box C, Chambers P, et al. Determinants of response to epidermal growth factor receptor tyrosine kinase inhibition in squamous cell carcinoma of the head and neck. J Pathol 2009;218:122-130.
    • (2009) J. Pathol. , vol.218 , pp. 122-130
    • Rogers, S.J.1    Box, C.2    Chambers, P.3
  • 35
    • 58149265465 scopus 로고    scopus 로고
    • Autocrine production of amphiregulin predicts sensitivity to both gefitinib and cetuximab in GFR wild-type cancers
    • Yonesaka K, Zejnullahu K, Lindeman N, et al. Autocrine production of amphiregulin predicts sensitivity to both gefitinib and cetuximab in GFR wild-type cancers. Clin Cancer Res 2008;14:6963-6973.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 6963-6973
    • Yonesaka, K.1    Zejnullahu, K.2    Lindeman, N.3
  • 37
    • 73349098041 scopus 로고    scopus 로고
    • Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab
    • Jacobs B, De Roock W, Piessevaux H, et al. Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab. J Clin Oncol 2009;27:5068-5074.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 5068-5074
    • Jacobs, B.1    De Roock, W.2    Piessevaux, H.3
  • 38
    • 33646576196 scopus 로고    scopus 로고
    • Ethnic differences in response to epidermal growth factor receptor tyrosine kinase inhibitors
    • DOI 10.1200/JCO.2006.06.5961
    • Calvo E, Baselga J. Ethnic differences in response to epidermal growth factor receptor tyrosine kinase inhibitors. J Clin Oncol 2006;24:2158-2163. (Pubitemid 46630688)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.14 , pp. 2158-2163
    • Calvo, E.1    Baselga, J.2
  • 39
    • 56749161670 scopus 로고    scopus 로고
    • Emerging ethnic differences in lung cancer therapy
    • Sekine I, Yamamoto N, Nishio K, et al. Emerging ethnic differences in lung cancer therapy. Br J Cancer 2008;99:1757-1762.
    • (2008) Br. J. Cancer , vol.99 , pp. 1757-1762
    • Sekine, I.1    Yamamoto, N.2    Nishio, K.3
  • 41
    • 34548853993 scopus 로고    scopus 로고
    • Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus
    • DOI 10.1158/1078-0432.CCR-07-0560
    • Riely GJ, Kris MG, Zhao B, et al. Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus. Clin Cancer Res 2007;13:5150-5155. (Pubitemid 47502083)
    • (2007) Clinical Cancer Research , vol.13 , Issue.17 , pp. 5150-5155
    • Riely, G.J.1    Kris, M.G.2    Zhao, B.3    Akhurst, T.4    Milton, D.T.5    Moore, E.6    Tyson, L.7    Pao, W.8    Rizvi, N.A.9    Schwartz, L.H.10    Miller, V.A.11
  • 42
    • 8344253460 scopus 로고    scopus 로고
    • Combination signal transduction inhibition: A phase I/II trial of the oral mTOR-inhibitor everolimus E RAD001 and imatinib mesylate IM in patients pts with gastrointestinal stromal tumor GIST refractory to IM
    • Meeting Abstracts
    • Van Oosterom AT, Dumez H, Desai J, et al. Combination signal transduction inhibition: a phase I/II trial of the oral mTOR-inhibitor everolimus (E, RAD001) and imatinib mesylate (IM) in patients (pts) with gastrointestinal stromal tumor (GIST) refractory to IM. J Clin Oncol (Meeting Abstracts) 2004;22:3002.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 3002
    • Van Oosterom, A.T.1    Dumez, H.2    Desai, J.3
  • 43
    • 35148837581 scopus 로고    scopus 로고
    • Mechanisms of Disease: Signaling of the insulin-like growth factor 1 receptor pathway - Therapeutic perspectives in cancer
    • DOI 10.1038/ncponc0934, PII NCPONC0934
    • Tao Y, Pinzi V, Bourhis J, et al. Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway-therapeutic perspectives in cancer. Nat Clin Pract Oncol 2007;4:591-602. (Pubitemid 47534758)
    • (2007) Nature Clinical Practice Oncology , vol.4 , Issue.10 , pp. 591-602
    • Tao, Y.1    Pinzi, V.2    Bourhis, J.3    Deutsch, E.4
  • 44
    • 4143066760 scopus 로고    scopus 로고
    • Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
    • DOI 10.1126/science.1101637
    • Sordella R, Bell DW, Haber DA, et al. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 2004;305:1163-1167. (Pubitemid 39100331)
    • (2004) Science , vol.305 , Issue.5687 , pp. 1163-1167
    • Sordella, R.1    Bell, D.W.2    Haber, D.A.3    Settleman, J.4
  • 45
    • 14844366111 scopus 로고    scopus 로고
    • ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines
    • USA
    • Engelman JA, Jänne PA, Mermel C, et al. ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines. Proc Natl Acad Sci USA 2005;102:3788-3793.
    • (2005) Proc. Natl. Acad. Sci. , vol.102 , pp. 3788-3793
    • Engelman, J.A.1    Jänne, P.A.2    Mermel, C.3
  • 46
    • 27944477029 scopus 로고    scopus 로고
    • Inhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib Iressa in human breast cancer cells
    • Camirand A, Zakikhani M, Young F, et al. Inhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib (Iressa) in human breast cancer cells. Breast Cancer Res 2005;7:R570-R579.
    • (2005) Breast. Cancer Res. , vol.7
    • Camirand, A.1    Zakikhani, M.2    Young, F.3
  • 47
    • 42149141146 scopus 로고    scopus 로고
    • Functionally significant insulin-like growth factor I receptor mutations in centenarians
    • USA
    • Suh Y, Atzmon G, Cho M, et al. Functionally significant insulin-like growth factor I receptor mutations in centenarians. Proc Natl Acad Sci USA 2008;105:3438-3442.
    • (2008) Proc. Natl. Acad. Sci. , vol.105 , pp. 3438-3442
    • Suh, Y.1    Atzmon, G.2    Cho, M.3
  • 49
    • 0031589538 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-3 induces apoptosis in MCF7 breast cancer cells
    • DOI 10.1006/bbrc.1997.7089
    • Nickerson T, Huynh H, Pollak M. Insulin-like growth factor binding protein-3 induces apoptosis in MCF7 breast cancer cells. Biochem Biophys Res Commun 1997;237:690-693. (Pubitemid 27434749)
    • (1997) Biochemical and Biophysical Research Communications , vol.237 , Issue.3 , pp. 690-693
    • Nickerson, T.1    Huynh, H.2    Pollak, M.3
  • 50
    • 0030972216 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-β1 on programmed cell death through a p53- and IGF-independent mechanism
    • DOI 10.1074/jbc.272.18.12181
    • Rajah R, Valentinis B, Cohen P. Insulin-like growth factor (IGF)- binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism. J Biol Chem 1997;272:12181-12188. (Pubitemid 27202802)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.18 , pp. 12181-12188
    • Rajah, R.1    Valentinis, B.2    Cohen, P.3
  • 51
    • 0033304507 scopus 로고    scopus 로고
    • The insulin-like growth factor-binding protein (IGFBP) superfamily
    • Hwa V, Oh Y, Rosenfeld RG. The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocr Rev 1999;20:761-787. (Pubitemid 30648894)
    • (1999) Endocrine Reviews , vol.20 , Issue.6 , pp. 761-787
    • Hwa, V.1    Oh, Y.2    Rosenfeld, R.G.3
  • 52
    • 33751076856 scopus 로고    scopus 로고
    • The prognostic significance of pretreatment plasma levels of insulin-like growth factor IGF-1 IGF-2 and IGF binding protein-3 in patients with advanced non-small cell lung cancer
    • Han JY, Choi BG, Choi JY, et al. The prognostic significance of pretreatment plasma levels of insulin-like growth factor (IGF)-1, IGF-2, and IGF binding protein-3 in patients with advanced non-small cell lung cancer. Lung Cancer 2006;54:227-234.
    • (2006) Lung Cancer , vol.54 , pp. 227-234
    • Han, J.Y.1    Choi, B.G.2    Choi, J.Y.3
  • 59
    • 34248590819 scopus 로고    scopus 로고
    • Alteration of the serum levels of the epidermal growth factor receptor and its ligands in patients with non-small cell lung cancer and head and neck carcinoma
    • Lemos-González Y, Rodríguez-Berrocal FJ, Cordero OJ, et al. Alteration of the serum levels of the epidermal growth factor receptor and its ligands in patients with non-small cell lung cancer and head and neck carcinoma. Br J Cancer 2007;96:1569-1578.
    • (2007) Br. J. Cancer , vol.96 , pp. 1569-1578
    • Lemos-González, Y.1    Rodríguez-Berrocal, F.J.2    Cordero, O.J.3
  • 60
    • 55449123441 scopus 로고    scopus 로고
    • Clinical significance of pretreatment serum amphiregulin and transforming growth factor-alpha and an epidermal growth factor receptor somatic mutation in patients with advanced nonsquamous nonsmall cell lung cancer
    • Masago K, Fujita S, Hatachi Y, et al Clinical significance of pretreatment serum amphiregulin and transforming growth factor-alpha, and an epidermal growth factor receptor somatic mutation in patients with advanced nonsquamous, nonsmall cell lung cancer. Cancer Sci 2008; 99:2295-2301.
    • (2008) Cancer Sci. , vol.99 , pp. 2295-2301
    • Masago, K.1    Fujita, S.2    Hatachi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.