Synthesis and evaluation of 15-(4-(2-[18F]Fluoroethoxy)phenyl) pentadecanoic Acid: A potential PET tracer for studying myocardial fatty acid metabolism

Bioconjugate Chemistry

Volumn 21, Issue 12, 2010, Pages 2313-2319

  Tu, Zhude ^a   Li, Shihong ^a   Sharp, Terry L ^a   Herrero, Pilar ^a   Dence, Carmen S ^a   Gropler, Robert J ^a   Mach, Robert H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METABOLISM; PHYSIOLOGY; RATS; SATURATED FATTY ACIDS; SULFUR COMPOUNDS;

BIOLOGICAL EVALUATION; FATTY ACID METABOLISM; PENTADECANOIC ACID; PET PROBE; PET TRACER; RADIOLABELLING; RADIOSYNTHESIS; SPECIFIC ACTIVITY; SYNTHESISED; TWO-STEP REACTIONS;

PALMITIC ACID;

15 [4 (2 FLUOROETHOXY)PHENYL] PENTADECANOIC ACID F 18; METHYL 15 (4 HYDROXYPHENYL)PENTADECANOATE; METHYL 15 [4 (2 FLUOROETHOXY)PHENYL] PENTADECANOATE; METHYL 15 [4 (BENZYLOXY)PHENYL] PENTADECANOATE; METHYL 15 [4 [2 (TOSYLOXY)ETHOXY] PHENYL] PENTADECANOATE; PALMITIC ACID C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; BRAIN; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; FATTY ACID METABOLISM; HEART; HEART MUSCLE; ISOTOPE LABELING; LUNG; MALE; MUSCLE; NONHUMAN; PANCREAS; POSITRON EMISSION TOMOGRAPHY; RADIOISOTOPE DECAY; RAT; SPRAGUE DAWLEY RAT;

ANIMALIA; RATTUS;

EID: 78650410901     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc100343h     Document Type: Article

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