Effect of FKBP65, a putative elastin chaperone, on the coacervation of tropoelastin in vitro

Biochemistry and Cell Biology

Volumn 88, Issue 6, 2010, Pages 917-925

  Cheung, Kevin L V ^a   Bates, Matthew ^a   Ananthanarayanan, Vettai S ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Circular dichroism; Coacervation; Elastin biosynthesis; Elastin model polypeptide; FKBP65; Molecular chaperone; Tropoelastin

Indexed keywords

CIRCULAR DICHROISM; COACERVATION; ELASTIN BIOSYNTHESIS; ELASTIN MODEL POLYPEPTIDE; FKBP65; MOLECULAR CHAPERONES; TROPOELASTIN;

BIOCHEMISTRY; BIOSYNTHESIS; DICHROISM; ESCHERICHIA COLI;

GLYCOPROTEINS;

CHAPERONE; FKBP12 PROTEIN; FKBP65 PROTEIN; ISOMERASE; RAPAMYCIN; RECOMBINANT PROTEIN; TROPOELASTIN; UNCLASSIFIED DRUG;

ARTICLE; COACERVATION; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ESCHERICHIA COLI; GENE EXPRESSION SYSTEM; IN VITRO STUDY; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; THERMOSTABILITY; TURBIDIMETRY;

ANIMALS; AORTA; CHICKENS; CIRCULAR DICHROISM; CLONING, MOLECULAR; ELASTIN; ENDOPLASMIC RETICULUM; ESCHERICHIA COLI; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR CHAPERONES; PEPTIDYLPROLYL ISOMERASE; RECOMBINANT PROTEINS; RETICULIN; SECRETORY PATHWAY; SIROLIMUS; TACROLIMUS BINDING PROTEINS; TROPOELASTIN;

EID: 78650400334     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/O10-137     Document Type: Article

References (38)

1. Bashir, M.M., Indik, Z., Yeh, H., Ornstein-Goldstein, N., Rosenbloom, J.C., Abrams, W., et al. 1989. Characterization of the complete human elastin gene. Delineation of unusual features in the 5′-flanking region. J. Biol. Chem. 264 (15): 8887-8891. 2722804
2. Bellingham, C.M., Woodhouse, K.A., Robson, P., Rothstein, S.J., and Keeley, F.W. 2001. Self-aggregation characteristics of recombinantly expressed human elastin polypeptides. Biochim. Biophys. Acta, 1550 (1): 6-19. 11738083
3. Bressan, G.M., Pasquali-Ronchetti, I., Fornieri, C., Mattioli, F., Castellani, I., and Volpin, D. 1986. Relevance of aggregation properties of tropoelastin to the assembly and structure of elastic fibers. J. Ultrastruct. Mol. Struct. Res. 94 (3): 209-216. 10.1016/0889-1605(86)90068-6 3805787 (Pubitemid 17066009)
4. Cirulis, J.T., Bellingham, C.M., Davis, E.C., Hubmacher, D., Reinhardt, D.P., Mecham, R.P., and Keeley, F.W. 2008. Fibrillins, fibulins, and matrix-associated glycoprotein modulate the kinetics and morphology of in vitro self-assembly of a recombinant elastin-like polypeptide. Biochemistry, 47 (47): 12601-12613. 10.1021/bi8005384 18973305
5. Cirulis, J.T., Keeley, F.W., and James, D.F. 2009. Viscoelastic properties and gelation of an elastin-like polypeptide. J. Rheol. (N.Y.N.Y.), 53: 1215-1228.
6. Coss, M.C., Winterstein, D., Sowder, R.C. II, and Simek, S.L. 1995. Molecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65). J. Biol. Chem. 270 (49): 29336-29341. 10.1074/jbc.270.49.29336 7493967
7. Davis, E.C., Broekelmann, T.J., Ozawa, Y., and Mecham, R.P. 1998. Identification of tropoelastin as a ligand for the 65-kD FK506-binding protein, FKBP65, in the secretory pathway. J. Cell Biol. 140 (2): 295-303. 10.1083/jcb.140.2.295 9442105 (Pubitemid 28078393)
8. Dridi, S.M., Foucault Bertaud, A., Igondjo Tchen, S., Senni, K., Ejeil, A.L., Pellat, B., et al. 2005. Vascular wall remodeling in patients with supravalvular aortic stenosis and Williams Beuren syndrome. J. Vasc. Res. 42 (3): 190-201. 10.1159/000085141 15832055 (Pubitemid 40981126)
9. Dyksterhuis, L.B., Baldock, C., Lammie, D., Wess, T.J., and Weiss, A.S. 2007. Domains 17-27 of tropoelastin contain key regions of contact for coacervation and contain an unusual turn-containing crosslinking domain. Matrix Biol. 26 (2): 125-135. 10.1016/j.matbio.2006.10.002 17129717 (Pubitemid 46187042)
10. Giersing, B., Miura, K., Shimp, R., Wang, J., Zhou, H., Orcutt, A., et al. 2005. Posttranslational modification of recombinant Plasmodium falciparum apical membrane antigen 1: impact on functional immune responses to a malaria vaccine candidate. Infect. Immun. 73 (7): 3963-3970. 10.1128/IAI.73.7.3963-3970. 2005 15972483 (Pubitemid 40923135)
11. Gill, S.C., and von Hippel, P.H. 1989. Calculation of protein extinction coefficients from amino acid sequence data. Anal. Biochem. 182 (2): 319-326. 10.1016/0003-2697(89)90602-7 2610349
12. Glaves, R., Baer, M., Schreiner, E., Stoll, R., and Marx, D. 2008. Conformational dynamics of minimal elastin-like polypeptides: the role of proline revealed by molecular dynamics and nuclear magnetic resonance. ChemPhysChem, 9 (18): 2759-2765. 10.1002/cphc.200800474 18972488
13. Hucthagowder, V., Morava, E., Kornak, U., Lefeber, D.J., Fischer, B., Dimopoulou, A., et al. 2009. Loss-of-function mutations in ATP6V0A2 impair vesicular trafficking, tropoelastin secretion and cell survival. Hum. Mol. Genet. 18 (12): 2149-2165. 10.1093/hmg/ddp148 19321599
14. Jensen, S.A., Vrhovski, B., and Weiss, A.S. 2000. Domain 26 of tropoelastin plays a dominant role in association by coacervation. J. Biol. Chem. 275 (37): 28449-28454. 10.1074/jbc.M004265200 10862774
15. Mecham, R.P., and Davis, E.C. 1994. Elastic fibre structure and assembly. In Extracellular matrix assembly and structure. Edited by P.D. Yurchenko, D.E. Birk, and R.P. Mecham. Academic Press, San Diego. pp. 281-314.
16. Miao, M., Bellingham, C.M., Stahl, R.J., Sitarz, E.E., Lane, C.J., and Keeley, F.W. 2003. Sequence and structure determinants for the self-aggregation of recombinant polypeptides modeled after human elastin. J. Biol. Chem. 278 (49): 48553-48562. 10.1074/jbc.M308465200 14500713 (Pubitemid 41079493)
17. Milewicz, D.M., Urbn, Z., and Boyd, C. 2000. Genetic disorders of the elastic fiber system. Matrix Biol. 19 (6): 471-480. 10.1016/S0945-053X(00)00099- 8 11068201
18. Ostuni, A., Bochicchio, B., Armentano, M.F., Bisaccia, F., and Tamburro, A.M. 2007. Molecular and supramolecular structural studies on human tropoelastin sequences. Biophys. J. 93 (10): 3640-3651. 10.1529/biophysj.107.110809 17693470 (Pubitemid 350190826)
19. Pemberton, T.J., and Kay, J.E. 2005. Identification and comparative analysis of the peptidyl-prolyl cis/trans isomerase repertoires of H. sapiens, D. melanogaster, C. elegans, S. cerevisiae and Sz. pombe. Comp. Funct. Genomics, 6 (5-6): 277-300. 10.1002/cfg.482 18629211 (Pubitemid 41319900)
20. Pepe, A., Guerra, D., Bochicchio, B., Quaglino, D., Gheduzzi, D., Pasquali Ronchetti, I., and Tamburro, A.M. 2005. Dissection of human tropoelastin: supramolecular organization of polypeptide sequences coded by particular exons. Matrix Biol. 24 (2): 96-109. 10.1016/j.matbio.2005.01.004 15890261 (Pubitemid 40693634)
21. Provencher, S.W., and Glckner, J. 1981. Estimation of globular protein secondary structure from circular dichroism. Biochemistry, 20 (1): 33-37. 10.1021/bi00504a006 7470476
22. Rauscher, S., Baud, S., Miao, M., Keeley, F.W., and Pomès, R. 2006. Proline and glycine control protein self-organization into elastomeric or amyloid fibrils. Structure, 14 (11): 1667-1676. 10.1016/j.str.2006.09.008 17098192 (Pubitemid 46107274)
23. Reiersen, H., Clarke, A.R., and Rees, A.R. 1998. Short elastin-like peptides exhibit the same temperature-induced structural transitions as elastin polymers: implications for protein engineering. J. Mol. Biol. 283 (1): 255-264. 10.1006/jmbi.1998.2067 9761688 (Pubitemid 28466654)
24. Rosenbloom, J., Abrams, W.R., and Mecham, R. 1993. Extracellular matrix 4: the elastic fiber. FASEB J. 7 (13): 1208-1218. 8405806
25. Rosenbloom, J., Abrams, W.R., Indik, Z., Yeh, H., Ornstein-Goldstein, N., and Bashir, M.M. 1995. Structure of the elastin gene. Ciba Found. Symp. 192: 59-74, discussion 74-80. 8575268
26. Tamburro, A.M., Bochicchio, B., and Pepe, A. 2003. Dissection of human tropoelastin: exon-by-exon chemical synthesis and related conformational studies. Biochemistry, 42 (45): 13347-13362. 10.1021/bi034837t 14609345 (Pubitemid 37420687)
27. Tamburro, A.M., Pepe, A., Bochicchio, B., Quaglino, D., and Ronchetti, I.P. 2005. Supramolecular amyloid-like assembly of the polypeptide sequence coded by exon 30 of human tropoelastin. J. Biol. Chem. 280 (4): 2682-2690. 10.1074/jbc.M411617200 15550396 (Pubitemid 40189373)
28. Thomson, C.A., and Ananthanarayanan, V.S. 2000. Structure-function studies on Hsp47: pH-dependent inhibition of collagen fibril formation in vitro. Biochem. J. 349 (Pt 3): 877-883. 10903151
29. Thyberg, J., Hinek, A., Nilsson, J., and Friberg, U. 1979. Electron microscopic and cytochemical studies of rat aorta. Intracellular vesicles containing elastin-and collagen-like material. Histochem. J. 11 (1): 1-17. 10.1007/BF01041263 218909
30. Toonkool, P., Jensen, S.A., Maxwell, A.L., and Weiss, A.S. 2001. Hydrophobic domains of human tropoelastin interact in a context-dependent manner. J. Biol. Chem. 276 (48): 44575-44580. 10.1074/jbc.M107920200 11564742
31. Tu, Y., and Weiss, A.S. 2010. Transient tropoelastin nanoparticles are early-stage intermediates in the coacervation of human tropoelastin whose aggregation is facilitated by heparan sulfate and heparin decasaccharides. Matrix Biol. 29 (2): 152-159. 10.1016/j.matbio.2009.10.003 19895887
32. Tu, Y., Wise, S.G., and Weiss, A.S. 2010. Stages in tropoelastin coalescence during synthetic elastin hydrogel formation. Micron, 41 (3): 268-272. 10.1016/j.micron.2009.11.003 19969467
33. Urry, D.W. 1978. Molecular perspectives of vascular wall structure and disease: the elastic component. Perspect. Biol. Med. 21 (2): 265-295. 643517
34. Urry, D.W., Starcher, B., and Partridge, S.M. 1969. Coacervation of solubilized elastin effects a notable conformational change. Nature, 222 (5195): 795-796. 10.1038/222795a0 5786200
35. Vrhovski, B., and Weiss, A.S. 1998. Biochemistry of tropoelastin. Eur. J. Biochem. 258 (1): 1-18. 10.1046/j.1432-1327.1998.2580001.x 9851686 (Pubitemid 28538302)
36. Vrhovski, B., Jensen, S., and Weiss, A.S. 1997. Coacervation characteristics of recombinant human tropoelastin. Eur. J. Biochem. 250 (1): 92-98. 10.1111/j.1432-1033.1997.00092.x 9431995
37. Woodhouse, K.A., Klement, P., Chen, V., Gorbet, M.B., Keeley, F.W., Stahl, R., et al. 2004. Investigation of recombinant human elastin polypeptides as non-thrombogenic coatings. Biomaterials, 25 (19): 4543-4553. 10.1016/j.biomaterials.2003.11.043 15120499 (Pubitemid 38561141)
38. Zeng, B., MacDonald, J.R., Bann, J.G., Beck, K., Gambee, J.E., Boswell, B.A., and Bchinger, H.P. 1998. Chicken FK506-binding protein, FKBP65, a member of the FKBP family of peptidylprolyl cis-trans isomerases, is only partially inhibited by FK506. Biochem. J. 330 (Pt 1): 109-114. 9461498