Barriers to living donor kidney transplantation among black or older transplant candidates

Clinical Journal of the American Society of Nephrology

Volumn 5, Issue 12, 2010, Pages 2338-2347

  Weng, Francis L ^a,b   Reese, Peter P ^c   Mulgaonkar, Shamkant ^a   Patel, Anup M ^a  

^a SAINT BARNABAS MEDICAL CENTER   (United States)

^b University of Medicine   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE DISTRIBUTION; ARTICLE; CADAVER KIDNEY; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HUMAN; KIDNEY DONOR; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; NEGRO; RACE DIFFERENCE; RETROSPECTIVE STUDY; RISK FACTOR; SEX DIFFERENCE;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGE FACTORS; AGED; COHORT STUDIES; FEMALE; HUMANS; KIDNEY TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; RETROSPECTIVE STUDIES;

EID: 78650391237     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.03040410     Document Type: Article

References (47)

1. U.S. Department of Health and Human Services, Health Resources and Services Administration, Healthcare Systems Bureau, Division of Transplantation: 2008 Annual Report of the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients: Transplant data 1998-2007. Rockville, MD, 2008
2. Gore JL, Danovitch GM, Litwin MS, Pham PT, Singer JS: Disparities in the utilization of live donor renal transplantation. Am J Transplant 9: 1124-1133, 2009
3. Reese PP, Shea JA, Bloom RD, Berns JS, Grossman R, Joffe M, Huverserian A, Feldman HI: Predictors of having a potential live donor: A prospective cohort study of kidney transplant candidates. Am J Transplant 9: 2792-2799, 2009
4. Segev DL, Kucirka LM, Oberai PC, Parekh RS, Boulware LE, Powe NR, Montgomery RA: Age and comorbidities are effect modifiers of gender disparities in renal transplantation. J Am Soc Nephrol 20: 621-628, 2009
5. U.S. Renal Data System: USRDS 2009 Annual data report: Atlas of chronic kidney disease and end-stage renal disease in the United States. Bethesda, MD, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2009
6. Schold J, Srinivas TR, Sehgal AR, Meier-Kriesche HU: Half of kidney transplant candidates who are older than 60 years now placed on the waiting list will die before receiving a deceased-donor transplant. Clin J Am Soc Nephrol 4: 1239-1245, 2009
7. Bloembergen WE, Port FK, Mauger EA, Briggs JP, Leichtman AB: Gender discrepancies in living related renal transplant donors and recipients. J Am Soc Nephrol 7: 1139-1144, 1996 (Pubitemid 27468264)
8. Kayler LK, Meier-Kriesche HU, Punch JD, Campbell DA, Jr., Leichtman AB, Magee JC, Rudich SM, Arenas JD, Merion RM: Gender imbalance in living donor renal transplantation. Transplantation 73: 248-252, 2002 (Pubitemid 34112849)
9. Kayler LK, Rasmussen CS, Dykstra DM, Ojo AO, Port FK, Wolfe RA, Merion RM: Gender imbalance and outcomes in living donor renal transplantation in the United States. Am J Transplant 3: 452-458, 2003
10. Tankersley M, Gaston RS, Curtis J, Julian B, Deierhoi M, Rhynes V, Zeigler S, Diethelm A: The living donor process in kidney transplantation: Influence of race and comorbidity. Transplant Proc 29: 3722-3723, 1997 (Pubitemid 28008663)
11. Norman SP, Song PX, Hu Y, Ojo AO: Transition from donor candidates to live kidney donors: The impact of race and undiagnosed medical disease states. Clin Transplant, 2009, Epub ahead of print
12. Reeves-Daniel A, Adams PL, Daniel K, Assimos D, Westcott C, Alcorn SG, Rogers J, Farney AC, Stratta RJ, Hartmann EL: Impact of race and gender on live kidney donation. Clin Transplant 23: 39-46, 2009
13. Lunsford SL, Simpson KS, Chavin KD, Menching KJ, Miles LG, Shilling LM, Smalls GR, Baliga PK: Racial disparities in living kidney donation: Is there a lack of willing donors or an excess of medically unsuitable candidates? Transplantation 82: 876-881, 2006
14. Hertz RP, Unger AN, Cornell JA, Saunders E: Racial disparities in hypertension prevalence, awareness, and management. Arch Intern Med 165: 2098-2104, 2005
15. Mokdad AH, Ford ES, Bowman BA, Dietz WH, Vinicor F, Bales VS, Marks JS: Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 289: 76-79, 2003
16. Davis CL, Delmonico FL: Living-donor kidney transplantation: A review of the current practices for the live donor. J Am Soc Nephrol 16: 2098-2110, 2005 (Pubitemid 41716441)
17. Kasiske BL, Ravenscraft M, Ramos EL, Gaston RS, Bia MJ, Danovitch GM: The evaluation of living renal transplant donors: Clinical practice guidelines. Ad Hoc Clinical Practice Guidelines Subcommittee of the Patient Care and Education Committee of the American Society of Transplant Physicians. J Am Soc Nephrol 7: 2288-2313, 1996
18. Mandelbrot DA, Pavlakis M, Danovitch GM, Johnson SR, Karp SJ, Khwaja K, Hanto DW, Rodrigue JR: The medical evaluation of living kidney donors: A survey of US transplant centers. Am J Transplant 7: 2333-2343, 2007 (Pubitemid 47347855)
19. Hosmer DW, Lemeshow S: Applied logistic regression, 2nd ed. New York, John Wiley & Sons, Inc., 2000
20. Rodrigue JR, Cornell DL, Lin JK, Kaplan B, Howard RJ: Increasing live donor kidney transplantation: A randomized controlled trial of a home-based educational intervention. Am J Transplant 7: 394-401, 2007 (Pubitemid 46096332)
21. Rodrigue JR, Cornell DL, Kaplan B, Howard RJ: A randomized trial of a home-based educational approach to increase live donor kidney transplantation: Effects in blacks and whites. Am J Kidney Dis 51: 663-670, 2008 (Pubitemid 351400838)
22. Schweitzer EJ, Yoon S, Hart J, Anderson L, Barnes R, Evans D, Hartman K, Jaekels J, Johnson LB, Kuo PC, Hoehn-Saric E, Klassen DK, Weir MR, Bartlett ST: Increased living donor volunteer rates with a formal recipient family education program. Am J Kidney Dis 29: 739-745, 1997 (Pubitemid 27209677)
23. Matas AJ, Bartlett ST, Leichtman AB, Delmonico FL: Morbidity and mortality after living kidney donation, 1999-2001: Survey of United States transplant centers. Am J Transplant 3: 830-834, 2003
24. Segev DL, Muzaale AD, Caffo BS, Mehta SH, Singer AL, Taranto SE, McBride MA, Montgomery RA: Perioperative mortality and long-term survival following live kidney donation. JAMA 303: 959-966, 2010
25. Boudville N, Prasad GV, Knoll G, Muirhead N, Thiessen-Philbrook H, Yang RC, Rosas-Arellano MP, Housawi A, Garg AX: Meta-analysis: Risk for hypertension in living kidney donors. Ann Intern Med 145: 185-196, 2006 (Pubitemid 46780564)
26. Garg AX, Muirhead N, Knoll G, Yang RC, Prasad GV, Thiessen-Philbrook H, Rosas-Arellano MP, Housawi A, Boudville N: Proteinuria and reduced kidney function in living kidney donors: A systematic review, meta-analysis, and meta-regression. Kidney Int 70: 1801-1810, 2006
27. Tavakol MM, Vincenti FG, Assadi H, Frederick MJ, Tomlanovich SJ, Roberts JP, Posselt AM: Long-term renal function and cardiovascular disease risk in obese kidney donors. Clin J Am Soc Nephrol 4: 1230-1238, 2009
28. Praga M, Hernandez E, Herrero JC, Morales E, Revilla Y, Diaz-Gonzalez R, Rodicio JL: Influence of obesity on the appearance of proteinuria and renal insufficiency after unilateral nephrectomy. Kidney Int 58: 2111-2118, 2000
29. Abecassis M, Adams M, Adams P, Arnold RM, Atkins CR, Barr ML, Bennett WM, Bia M, Briscoe DM, Burdick J, Corry RJ, Davis J, Delmonico FL, Gaston RS, Harmon W, Jacobs CL, Kahn J, Leichtman A, Miller C, Moss D, Newmann JM, Rosen LS, Siminoff L, Spital A, Starnes VA, Thomas C, Tyler LS, Williams L, Wright FH, Youngner S: Consensus statement on the live organ donor. JAMA 284: 2919-2926, 2000
30. Haririan A, Nogueira J, Kukuruga D, Schweitzer E, Hess J, Gurk-Turner C, Jacobs S, Drachenberg C, Bartlett S, Cooper M: Positive cross-match living donor kidney transplantation: Longer-term outcomes. Am J Transplant 9: 536-542, 2009
31. Montgomery RA, Zachary AA, Ratner LE, Segev DL, Hiller JM, Houp J, Cooper M, Kavoussi L, Jarrett T, Burdick J, Maley WR, Melancon JK, Kozlowski T, Simpkins CE, Phillips M, Desai A, Collins V, Reeb B, Kraus E, Rabb H, Leffell MS, Warren DS: Clinical results from transplanting incompatible live kidney donor/recipient pairs using kidney paired donation. JAMA 294: 1655-1663, 2005
32. Montgomery RA, Locke JE, King KE, Segev DL, Warren DS, Kraus ES, Cooper M, Simpkins CE, Singer AL, Stewart ZA, Melancon JK, Ratner L, Zachary AA, Haas M: ABO incompatible renal transplantation: A paradigm ready for broad implementation. Transplantation 87: 1246-1255, 2009
33. Roodnat JI, Kal-van Gestel JA, Zuidema W, van Noord MA, van de Wetering J, IJzermans JNM, Weimar W: Successful expansion of the living donor pool by alternative living donation programs. Am J Transplant 9: 2150-2156, 2009
34. Segev DL, Kucirka LM, Gentry SE, Montgomery RA: Utilization and outcomes of kidney paired donation in the United States. Transplantation 86: 502-510, 2008
35. Zimmerman D, Donnelly S, Miller J, Stewart D, Albert SE: Gender disparity in living renal transplant donation. Am J Kidney Dis 36: 534-540, 2000
36. Tuohy KA, Johnson S, Khwaja K, Pavlakis M: Gender disparities in the live kidney donor evaluation process. Transplantation 82: 1402-1407, 2006
37. Alexander GC, Sehgal AR: Barriers to cadaveric renal transplantation among blacks, women, and the poor. JAMA 280: 1148-1152, 1998
38. Gill JS, Johnston O: Access to kidney transplantation: The limitations of our current understanding. J Nephrol 20: 501-506, 2007
39. Reese PP, Feldman HI, McBride MA, Anderson K, Asch DA, Bloom RD: Substantial variation in the acceptance of medically complex live kidney donors across US renal transplant centers. Am J Transplant 8: 2062-2070, 2008
40. Kasiske BL, Cangro CB, Hariharan S, Hricik DE, Kerman RH, Roth D, Rush DN, Vazquez MA, Weir MR: The evaluation of renal transplantation candidates: Clinical practice guidelines. Am J Transplant 1[Suppl 2]: 1-95, 2001
41. Waterman AD, Rodrigue JR, Purnell TS, Ladin K, Boulware LE: Addressing racial and ethnic disparities in live donor kidney transplantation: Priorities for research and intervention. Semin Nephrol 30: 90-98, 2010
42. Powe NR: Let's get serious about racial and ethnic disparities. J Am Soc Nephrol 19: 1271-1275, 2008
43. Ladin K, Hanto DW: Understanding disparities in transplantation: Do social networks provide the missing clue? Am J Transplant 10: 472-476, 2010
44. Boulware LE, Meoni LA, Fink NE, Parekh RS, Kao WH, Klag MJ, Powe NR: Preferences, knowledge, communication and patient-physician discussion of living kidney transplantation in African American families. Am J Transplant 5: 1503-1512, 2005
45. Winkelmayer WC, Mehta J, Chandraker A, Owen WF Jr, Avorn J: Predialysis nephrologist care and access to kidney transplantation in the United States. Am J Transplant 7: 872-879, 2007
46. Waterman AD, Barrett AC, Stanley SL: Optimal transplant education for recipients to increase pursuit of living donation. Prog Transplant 18: 55-62, 2008
47. Powe NR, Boulware LE: The uneven distribution of kidney transplants: Getting at the root causes and improving care. Am J Kidney Dis 40: 861-863, 2002