Interstitium: The next diagnostic and therapeutic platform in critical illness

Critical Care Medicine

Volumn 38, Issue 10 SUPPL., 2010, Pages

  Venkatesh, Bala ^a   Morgan, Thomas J ^b   Cohen, Jeremy ^c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b Mater Misericordiae Hospital   (Australia)

^c ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

Critical Care; Interstitium; Monitoring; Pathophysiology; Plasma

Indexed keywords

ACID BASE BALANCE; CONFERENCE PAPER; CRITICAL ILLNESS; DIAGNOSTIC PROCEDURE; ELECTROLYTE BALANCE; HEAD INJURY; HUMAN; INTERSTITIAL FLUID; INTERSTITIAL MONITORING; INTERSTITIUM; OXYGENATION; PATHOPHYSIOLOGY; PATIENT MONITORING; PRIORITY JOURNAL;

EID: 78650381972     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181f24406     Document Type: Conference Paper

References (80)

1. Shoemaker WC: Relation of oxygen transport patterns to the pathophysiology and therapy of shock states. Intensive Care Med 1987;13:230-243
2. Gattinoni L, Brazzi L, Pelosi P, et al: A trial of goal-oriented hemodynamic therapy in critically ill patients. SvO2 Collaborative Group. N Engl J Med 1995;333:1025-1032
3. Bakker J, Vincent JL, Gris P, et al: Venoarterial carbon dioxide gradient in human septic shock. Chest 1992;101:509-515
4. Siggaard-Andersen O, Gøthgen IH, Wimberley PD, et al: The oxygen status of the arterial blood revised: Relevant oxygen parameters for monitoring the arterial oxygen availability. Scand J Clin Lab Invest Suppl 1990;203:17-28
5. Ince C, Sinaasappel M: Microcirculatory oxygenation and shunting in sepsis and shock. Crit Care Med 1999;27:1369-1377
6. Fink M. Cytopathic hypoxia in sepsis. Acta Anaesthesiol Scand Suppl 1997;110:87-95
7. Venkatesh B, Morgan TJ: Monitoring tissue gas tensions in critical illness. Crit Care Resusc 2002;4:291-300
8. Venkatesh B, Hendry SP: Continuous intraarterial blood gas monitoring. Intensive Care Med 1996;22:818-828
9. Venkatesh B: Continuous intra-arterial blood gas monitoring. Crit Care Resusc 1999;1:150
10. Lee GJ, Park JH, Park HK: Microdialysis applications in neuroscience. Neurol Res 2008;30:661-668
11. Simpson JA, Lobo DN, Anderson JA, et al: Body water compartment measurements: A comparison of bioelectrical impedance analysis with tritium and sodium bromide dilution techniques. Clin Nutr 2001;20:339-343
12. Cheng AT, Plank LD, Hill GL: Prolonged overexpansion of extracellular water in elderly patients with sepsis. Arch Surg 1998;133:745-751
13. Plank LD, Connolly AB, Hill GL: Sequential changes in the metabolic response in severely septic patients during the first 23 days after the onset of peritonitis. Ann Surg 1998;228:146-158
14. Plank LD, Hill GL: Sequential metabolic changes following induction of systemic inflammatory response in patients with severe sepsis or major blunt trauma. World J Surg 2000;24:630-638
15. Finn PJ, Plank LD, Clark MA, et al: Progressive cellular dehydration and proteolysis in critically ill patients. Lancet 1996;347:654-656
16. Robin ED: Special report: Dysoxia. Abnormal tissue oxygen utilization. Arch Intern Med 1977;137:905-910
17. Fiddian-Green R: A sensitive and a specific diagnostic test for intestinal ischaemia using silastic tonometers. Abstr. Eur Surg J 1984;16(Suppl): A32
18. Gutierrez G, Palizas F, Doglio G, et al: Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients. Lancet 1992;339:195-199
19. Venkatesh B, Morgan J, Jones RD, et al: Validation of air as an equilibration medium in gastric tonometry: An in vitro evaluation of two techniques for measuring air PCO2. Anaesth Intensive Care 1998;26:46-50
20. Venkatesh B, Morgan TJ, Hall J, et al: Subcutaneous gas tensions closely track ileal mucosal gas tensions in a model of endotoxaemia without anaerobism. Intensive Care Med 2005;31:447-453
21. Vallet B, Teboul JL, Cain S, et al: Venoarterial CO (2) difference during regional ischemic or hypoxic hypoxia. J Appl Physiol 2000;89:1317-1321
22. Venkatesh B, Clutton Brock TH, Hendry SP. A multiparameter sensor for continuous intra-arterial blood gas monitoring: A prospective evaluation. Crit Care Med 1994;22:588-594
23. Nandi P, Lunte SM: Recent trends in microdialysis sampling integrated with conventional and microanalytical systems for monitoring biological events: A review. Anal Chim Acta 2009;651:1-14
24. Maurer MH: Proteomics of brain extracellular fluid (ECF) and cerebrospinal fluid (CSF). Mass Spectrom Rev 2010;29:17-28
25. Severinghaus JW, Astrup PB: History of blood gas analysis. Int Anesthesiol Clin 1987;25:1-115
26. Zauner A, Bullock R, Di X, et al: Brain oxygen, CO2, pH and temperature monitoring: Evaluation in the feline brain. Neurosurgery 1995;37:1168-1176
27. Hoffman WE, Charbel FT, Edelman G, et al: Brain tissue oxygen pressure, carbon dioxide pressure and pH during ischemia. Neurol Res 1996;18:54-56 (Pubitemid 26060391)
28. Fiddian-Green RG: Gastric intramucosal pH, tissue oxygenation and acid-base balance. Br J Anaesth 1995;74:591-606
29. Knichwitz G, Rotker J, Molhoff T, et al: Continuous intramucosal PCO2 measurement allows the early detection of intestinal malperfusion. Crit Care Med 1998;26:1550-1557
30. Morgan TJ, Venkatesh B, Endre ZH: Continuous measurement of gut luminal PCO2 in the rat: Responses to transient episodes of graded aortic hypotension. Crit Care Med 1997;25:1575-1578
31. Venkatesh B, Morgan TJ, Lipman J: Subcutaneous oxygen tensions provide similar information to ileal luminal CO2 tensions in an animal model of haemorrhagic shock. Intensive Care Med 2000;26:592-600
32. Nakagawa Y, Weil MH, Tang W, et al: Sublingual capnometry for diagnosis and quantitation of circulatory shock. Am J Respir Crit Care Med 1998;157:1838-1843
33. McKinley BA, Parmley CL, Butler BD: Skeletal muscle PO2, PCO2, and pH in hemorrhage, shock, and resuscitation in dogs. J Trauma 1998;44:119-127
34. Rosser DM, Stidwill RP, Jacobson D, et al: Oxygen tension in the bladder epithelium rises in both high and low cardiac output endotoxemic sepsis. J Appl Physiol 1995;79:1878-1882
35. Soini HO, Takala J, Nordin AJ, et al: Peripheral and liver tissue oxygen tensions in hemorrhagic shock. Crit Care Med 1992;20:1330-1334
36. Venkatesh B, Boots R, Tomlinson F, et al: The continuous measurement of cerebrospinal fluid gas tensions in critically ill neurosurgical patients: A prospective observational study. Intensive Care Med 1999;25:599-605
37. Schlichtig R, Bowles SA: Distinguishing between aerobic and anaerobic appearance of dissolved CO2 in intestine during low flow. J Appl Physiol 1994;76:2443-2451
38. Greif R, Akca O, Horn EP, et al: Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. Outcomes Research Group. N Engl J Med 2000;342:161-167
39. Gomersall CD, Joynt GM, Freebairn RC, et al: Resuscitation of critically ill patients based on the results of gastric tonometry: A prospective, randomized, controlled trial. Crit Care Med 2000;28:607-614
40. Kellum JA: Lactate and pHi: Our continued search for markers of tissue distress. Crit Care Med 1998;26:1783-1784
41. Bernardin G, Pradier C, Tiger F, et al: Blood pressure and arterial lactate level are early indicators of short-term survival in human septic shock. Intensive Care Med 1996;22:17-25
42. Gutierrez G, Wulf ME: Lactic acidosis in sepsis: A commentary. Intensive Care Med 1996;22:6-16
43. Duke T: Dysoxia and lactate. Arch Dis Child 1999;81:343-350
44. Venkatesh B, Morgan T: Tissue lactate concentrations in critical illness. In: Year Book of Intensive Care and Emergency Medicine. Vincent J, (Ed). New York, NY, Springer-Verlag, 2002, pp. 587-599
45. Ellmerer M, Schaupp L, Trajanoski Z, et al: Continuous measurement of subcutaneous lactate concentration during exercise by combining open-flow microperfusion and thin-film lactate sensors. Biosens Bioelectron 1998;13:1007-1013
46. Ignatov SG, Ferguson JA, Walt DR: A fiberoptic lactate sensor based on bacterial cytoplasmic membranes. Biosens Bioelectron 2001;16:109-113
47. Silva MA, Murphy N, Richards DA, et al: Interstitial lactic acidosis in the graft during organ harvest, cold storage, and reperfusion of human liver allografts predicts subsequent ischemia reperfusion injury. Transplantation 2006;82:227-233
48. Morgan T, Venkatesh B: The case for tissue base excess. In: Year Book of Intensive Care and Emergency Medicine. Vincent J, (Ed). New York, NY, Springer-Verlag, 2003, pp. 564-573
49. Morgan TJ, Clark C, Endre ZH: Accuracy of base excess-an in vitro evaluation of the Van Slyke equation. Crit Care Med 2000;28:2932-2936
50. Morgan TJ: The Stewart approach-One clinician's perspective. Clin Biochem Rev 2009;30:41-54
51. Hermus AR, Sweep CG: Cytokines and the hypothalamic-pituitary-adrenal axis. J Steroid Biochem Mol Biol 1990;37:867-871
52. Venkatesh B, Mortimer RH, Couchman B, et al: Evaluation of random plasma cortisol and the low dose corticotropin test as indicators of adrenal secretory capacity in critically ill patients: A prospective study. Anaesth Intensive Care 2005;33:201-209
53. Venkatesh B, Cohen J: Sick adrenal or sick euadrenal? Crit Care Resusc 2009;11:301-304
54. Cohen J, Ward G, Prins J, et al: Variability of cortisol assays can confound the diagnosis of adrenal insufficiency in the critically ill population. Intensive Care Med 2006;32:1901-1905
55. Cohen J, Venkatesh B: Assessment of tissue cortisol activity. Crit Care Resusc 2009;11:287-289
56. Pemberton PA, Stein PE, Pepys MB, et al: Hormone binding globulins undergo serpin conformational change in inflammation. Nature 1988;336:257-258
57. Fruchter O, Zoumakis E, Alesci S, et al: Intracrine modulation of gene expression by intracellular generation of active glucocorticoids. Steroids 2006;71:1001-1006
58. Cohen J, Deans R, Dalley A, et al: Measurement of tissue cortisol levels in patients with severe burns: A preliminary investigation. Crit Care 2009;13: R189
59. Goodman JC, Robertson CS: Microdialysis::is it ready for prime time? Curr Opin Crit Care 2009;15:110-117
60. Hashemi P, Bhatia R, Nakamura H, et al: Persisting depletion of brain glucose following cortical spreading depression, despite apparent hyperaemia: Evidence for risk of an adverse effect of Leao's spreading depression. J Cereb Blood Flow Metab 2009;29:166-175
61. Wang E, Ho CL, Lee KK, et al: Effects of temperature changes on cerebral biochemistry in spontaneous intracerebral hematoma. Acta Neurochir Suppl 2008;102:335-338
62. Bellander BM, Cantais E, Enblad P, et al: Consensus meeting on microdialysis in neurointensive care. Intensive Care Med 2004;30:2166-2169
63. Thallinger C, Buerger C, Plock N, et al: Effect of severity of sepsis on tissue concentrations of linezolid. J Antimicrob Chemother 2008;61:173-176
64. Zeitlinger MA, Dehghanyar P, Mayer BX, et al: Relevance of soft-tissue penetration by levofloxacin for target site bacterial killing in patients with sepsis. Antimicrob Agents Chemother 2003;47:3548-3553
65. Dalley AJ, Lipman J, Deans R, et al: Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers. Antimicrob Agents Chemother 2009;53:210-215
66. Joukhadar C, Klein N, Mayer BX, et al: Plasma and tissue pharmacokinetics of cefpirome in patients with sepsis. Crit Care Med 2002;30:1478-1482
67. Roberts JA, Roberts MS, Robertson TA, et al: Piperacillin penetration into tissue of critically ill patients with sepsis-bolus versus continuous administration? Crit Care Med 2009;37:926-933
68. Roberts JA, Kirkpatrick CM, Roberts MS, et al: Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. J Antimicrob Chemother 2009;64:142-150
69. Lubbers DW, Baumgartl H: Heterogeneities and profiles of oxygen pressure in brain and kidney as examples of the pO2 distribution in the living tissue. Kidney Int 1997;51:372-380
70. Zeitlinger MA, Traunmuller F, Abrahim A, et al: A pilot study testing whether concentrations of levofloxacin in interstitial space fluid of soft tissues may serve as a surrogate for predicting its pharmacokinetics in lung. Int J Antimicrob Agents 2007;29:44-50
71. Tamborlane WV, Beck RW, Bode BW, et al: Continuous glucose monitoring and intensive treatment of type 1 diabetes. N Engl J Med 2008;359:1464-1476
72. Waelgaard L, Thorgersen EB, Line PD, et al: Microdialysis monitoring of liver grafts by metabolic parameters, cytokine production, and complement activation. Transplantation 2008;86:1096-1103
73. Maurer MH, Haux D, Sakowitz OW, et al: Identification of early markers for symptomatic vasospasm in human cerebral microdialysate after subarachnoid hemorrhage: Preliminary results of a proteome-wide screening. J Cereb Blood Flow Metab 2007;27:1675-1683
74. Jain KK: Applications of nanobiotechnology in clinical diagnostics. Clin Chem 2007;53:2002-2009
75. Magder S: Intracellular [H+]. Second Edition. In: Stewart's Textbook of Acid Base. Kellum J, Elbers P (Eds). www.acidbase.org, 2009, pp 247-266
76. Heard SO, Helsmoortel CM, Kent JC: Gastric tonometry in healthy volunteers: Effect of ranitidine on calculated intramural pH. Crit Care Med 1991;19:271-274
77. Bohlen HG: Intestinal tissue PO2 and microvascular responses during glucose exposure. Am J Physiol 1980;238: H164-H171
78. Dahn MS, Wilson RF, Lange P, et al: Hepatic parenchymal oxygen tension following injury and sepsis. Arch Surg 1990;125:441-443
79. Venkatesh B, Meacher R, Muller MJ, et al: Monitoring tissue oxygenation during resuscitation of major burns. J Trauma 2001;50:485-494
80. Boekstegers P, Weidenhofer S, Kapsner T, et al: Skeletal muscle partial pressure of oxygen in patients with sepsis. Crit Care Med 1994;22:640-650