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Volumn 22, Issue 1, 2011, Pages 30-38

Update and new trends in antiemetic therapy: The continuing need for novel therapies

Author keywords

Aprepitant; Breakthrough; Casopitant; CINV; Palonosetron

Indexed keywords

ANTIEMETIC AGENT; APREPITANT; BENZAMIDE DERIVATIVE; BENZODIAZEPINE DERIVATIVE; BUTYROPHENONE DERIVATIVE; CANNABINOID DERIVATIVE; CASOPITANT; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOCETAXEL; DOLASETRON MESILATE; DOPAMINE RECEPTOR BLOCKING AGENT; DRONABINOL; FOSAPREPITANT; GRANISETRON; ITRACONAZOLE; METOCLOPRAMIDE; NEUROKININ 1 RECEPTOR ANTAGONIST; ONDANSETRON; ORAL CONTRACEPTIVE AGENT; PALONOSETRON; PHENOTHIAZINE DERIVATIVE; PHENYTOIN; PLACEBO; SEROTONIN 3 ANTAGONIST; TERFENADINE; TROPISETRON; UNINDEXED DRUG; WARFARIN;

EID: 78650375895     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdq600     Document Type: Review
Times cited : (115)

References (66)
  • 1
    • 47249165621 scopus 로고    scopus 로고
    • Chemotherapy-induced nausea and vomiting
    • Lohr L. Chemotherapy-induced nausea and vomiting. Cancer J 2008; 14: 85-93.
    • (2008) Cancer J , vol.14 , pp. 85-93
    • Lohr, L.1
  • 3
    • 78650311716 scopus 로고    scopus 로고
    • NCCN. National Comprehensive Cancer Network: Antiemesis, Clinical Practice Guidelines in Oncology-v.1. 2010. (4 October 2010, date last accessed)
    • NCCN. National Comprehensive Cancer Network: Antiemesis, Clinical Practice Guidelines in Oncology-v.1. 2010. www.nccn.org (4 October 2010, date last accessed).
  • 4
    • 0038185163 scopus 로고    scopus 로고
    • Differential involvement of neurotransmitters through the time course of cisplatin-induced emesis as revealed by therapy with specific receptor antagonists
    • Hesketh PJ, Van Belle S, Aapro M et al. Differential involvement of neurotransmitters through the time course of cisplatin-induced emesis as revealed by therapy with specific receptor antagonists. Eur J Cancer 2003; 39: 1074-1080.
    • (2003) Eur J Cancer , vol.39 , pp. 1074-1080
    • Hesketh, P.J.1    Van Belle, S.2    Aapro, M.3
  • 5
    • 44849134443 scopus 로고    scopus 로고
    • Chemotherapy-induced nausea and vomiting
    • Hesketh PJ. Chemotherapy-induced nausea and vomiting. N Engl J Med 2008; 358: 2482-2494.
    • (2008) N Engl J Med , vol.358 , pp. 2482-2494
    • Hesketh, P.J.1
  • 6
    • 29844438029 scopus 로고    scopus 로고
    • Prevention of chemotherapy- and radiotherapyinduced emesis: results of the 2004 Perugia International Antiemetic Consensus Conference
    • Roila F, Hesketh PJ, Herrstedt J. Prevention of chemotherapy- and radiotherapyinduced emesis: results of the 2004 Perugia International Antiemetic Consensus Conference. Ann Oncol 2006; 17: 20-28.
    • (2006) Ann Oncol , vol.17 , pp. 20-28
    • Roila, F.1    Hesketh, P.J.2    Herrstedt, J.3
  • 7
    • 33745515076 scopus 로고    scopus 로고
    • American Society of Clinical Oncology guideline for antiemetics in oncology: update 2006
    • Kris MG, Hesketh PJ, Somerfield MR et al. American Society of Clinical Oncology guideline for antiemetics in oncology: update 2006. J Clin Oncol 2006; 24: 2932-2947.
    • (2006) J Clin Oncol , vol.24 , pp. 2932-2947
    • Kris, M.G.1    Hesketh, P.J.2    Somerfield, M.R.3
  • 8
    • 0030609853 scopus 로고    scopus 로고
    • Use of an NK1 receptor antagonist to prevent delayed emesis after cisplatin
    • Kris MG, Radford JE, Pizzo BA et al. Use of an NK1 receptor antagonist to prevent delayed emesis after cisplatin. J Natl Cancer Inst 1997; 89: 817-818.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 817-818
    • Kris, M.G.1    Radford, J.E.2    Pizzo, B.A.3
  • 9
    • 67650685575 scopus 로고    scopus 로고
    • Evidence for a re-evaluation of the neurochemical and anatomical bases of chemotherapy-induced vomiting
    • Darmani NA, Ray AP. Evidence for a re-evaluation of the neurochemical and anatomical bases of chemotherapy-induced vomiting. Chem Rev 2009; 109: 3158-3199.
    • (2009) Chem Rev , vol.109 , pp. 3158-3199
    • Darmani, N.A.1    Ray, A.P.2
  • 10
    • 0020958904 scopus 로고
    • Responses of neurons of canine area postrema to neurotransmitters and peptides
    • Carpenter DO, Briggs DB, Strominger N. Responses of neurons of canine area postrema to neurotransmitters and peptides. Cell Mol Neurobiol 1983; 3: 113-126.
    • (1983) Cell Mol Neurobiol , vol.3 , pp. 113-126
    • Carpenter, D.O.1    Briggs, D.B.2    Strominger, N.3
  • 11
    • 14544288652 scopus 로고    scopus 로고
    • Should 5-hydroxytryptamine-3 receptor antagonists be administered beyond 24 hours after chemotherapy to prevent delayed emesis? Systematic re-evaluation of clinical evidence and drug cost implications
    • Geling O, Eichler H. Should 5-hydroxytryptamine-3 receptor antagonists be administered beyond 24 hours after chemotherapy to prevent delayed emesis? Systematic re-evaluation of clinical evidence and drug cost implications. J Clin Oncol 2005; 23: 1289-1294.
    • (2005) J Clin Oncol , vol.23 , pp. 1289-1294
    • Geling, O.1    Eichler, H.2
  • 12
    • 0032847992 scopus 로고    scopus 로고
    • Recommendations for the use of antiemetics: evidence-based, clinical practice guidelines. American Society of Clinical Oncology
    • Gralla R, Osoba D, Kris M et al. Recommendations for the use of antiemetics: evidence-based, clinical practice guidelines. American Society of Clinical Oncology. J Clin Oncol 1999; 17: 2971-2994.
    • (1999) J Clin Oncol , vol.17 , pp. 2971-2994
    • Gralla, R.1    Osoba, D.2    Kris, M.3
  • 13
    • 20244390153 scopus 로고    scopus 로고
    • Consensus proposals for the prevention of acute and delayed vomiting and nausea following high-emetic-risk chemotherapy
    • Kris MG, Hesketh PJ, Herrstedt J et al. Consensus proposals for the prevention of acute and delayed vomiting and nausea following high-emetic-risk chemotherapy. Support Care Cancer 2005; 13: 85-96.
    • (2005) Support Care Cancer , vol.13 , pp. 85-96
    • Kris, M.G.1    Hesketh, P.J.2    Herrstedt, J.3
  • 14
    • 17644411473 scopus 로고    scopus 로고
    • Acute emesis: moderately emetogenic chemotherapy
    • Herrstedt J, Koeller JM, Roila F et al. Acute emesis: moderately emetogenic chemotherapy. Support Care Cancer 2005; 13: 97-103.
    • (2005) Support Care Cancer , vol.13 , pp. 97-103
    • Herrstedt, J.1    Koeller, J.M.2    Roila, F.3
  • 15
    • 77954319603 scopus 로고    scopus 로고
    • Guideline update for MASCC and ESMO in the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting: results of the Perugia consensus conference
    • Roila F, Herrstedt J, Aapro M et al. Guideline update for MASCC and ESMO in the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting: results of the Perugia consensus conference. Ann Oncol 2010; 21 (Suppl 5): v232-v243.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL 5
    • Roila, F.1    Herrstedt, J.2    Aapro, M.3
  • 16
    • 33745782052 scopus 로고    scopus 로고
    • Novel neurokinin-1 antagonists as antiemetics for the treatment of chemotherapy-induced emesis
    • Reddy GK, Gralla RJ, Hesketh PJ. Novel neurokinin-1 antagonists as antiemetics for the treatment of chemotherapy-induced emesis. Support Cancer Ther 2006; 3: 140-142.
    • (2006) Support Cancer Ther , vol.3 , pp. 140-142
    • Reddy, G.K.1    Gralla, R.J.2    Hesketh, P.J.3
  • 17
    • 78650361813 scopus 로고    scopus 로고
    • (4 October 2010, date last accessed)
    • www.clinicaltrials.gov/ct2/results?term=rolapitant (4 October 2010, date last accessed).
  • 18
    • 0347816226 scopus 로고    scopus 로고
    • The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin-the Aprepitant Protocol 052 Study Group
    • Hesketh P, Grunberg S, Gralla R et al. The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin-the Aprepitant Protocol 052 Study Group. J Clin Oncol 2003; 21: 4112-4119.
    • (2003) J Clin Oncol , vol.21 , pp. 4112-4119
    • Hesketh, P.1    Grunberg, S.2    Gralla, R.3
  • 19
    • 0038728753 scopus 로고    scopus 로고
    • Addition of the neurokinin 1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting. Results from a randomized, double-blind, placebo-controlled trial in Latin America
    • Poli-Bigelli S, Rodrigues-Pereira J, Carides AD et al. Addition of the neurokinin 1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting. Results from a randomized, double-blind, placebo-controlled trial in Latin America. Cancer 2003; 97: 3090-3098.
    • (2003) Cancer , vol.97 , pp. 3090-3098
    • Poli-Bigelli, S.1    Rodrigues-Pereira, J.2    Carides, A.D.3
  • 20
    • 33646890831 scopus 로고    scopus 로고
    • Comparison of an aprepitant regimen with a multiple-day ondansetron regimen, both with dexamethasone, for antiemetic efficacy in high-dose cisplatin treatment
    • Schmoll HJ, Aapro MS, Poli-Bigelli S et al. Comparison of an aprepitant regimen with a multiple-day ondansetron regimen, both with dexamethasone, for antiemetic efficacy in high-dose cisplatin treatment. Ann Oncol 2006; 17: 1000-1006.
    • (2006) Ann Oncol , vol.17 , pp. 1000-1006
    • Schmoll, H.J.1    Aapro, M.S.2    Poli-Bigelli, S.3
  • 21
    • 20444482460 scopus 로고    scopus 로고
    • The oral NK(1) antagonist aprepitant for the prevention of acute and delayed chemotherapy-induced nausea and vomiting: pooled data from 2 randomised, double-blind, placebo controlled trials
    • Warr D, Grunberg SM, Gralla RJ et al. The oral NK(1) antagonist aprepitant for the prevention of acute and delayed chemotherapy-induced nausea and vomiting: pooled data from 2 randomised, double-blind, placebo controlled trials. Eur J Cancer 2005; 41: 1278-1285.
    • (2005) Eur J Cancer , vol.41 , pp. 1278-1285
    • Warr, D.1    Grunberg, S.M.2    Gralla, R.J.3
  • 22
    • 0036604223 scopus 로고    scopus 로고
    • Prevention of cisplatin-induced acute and delayed emesis by the selective neurokinin-1 antagonists, L-758 298 and MK-869
    • Van Belle S, Lichinitser MR, Navari RM et al. Prevention of cisplatin-induced acute and delayed emesis by the selective neurokinin-1 antagonists, L-758,298 and MK-869. Cancer 2002; 94: 3032-3041.
    • (2002) Cancer , vol.94 , pp. 3032-3041
    • Van Belle, S.1    Lichinitser, M.R.2    Navari, R.M.3
  • 23
    • 27644482810 scopus 로고    scopus 로고
    • Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin
    • Depre M, Van Hecken A, Oeyen M et al. Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin. Eur J Clin Pharmacol 2005; 61: 341-346.
    • (2005) Eur J Clin Pharmacol , vol.61 , pp. 341-346
    • Depre, M.1    Van Hecken, A.2    Oeyen, M.3
  • 24
    • 1242321114 scopus 로고    scopus 로고
    • Evaluation of potential inductive effects of aprepitant on cytochrome P450 3A4 and 2C9 activity
    • Shadle CR, Lee Y, Majumdar AK et al. Evaluation of potential inductive effects of aprepitant on cytochrome P450 3A4 and 2C9 activity. J Clin Pharmacol 2004; 44: 215-223.
    • (2004) J Clin Pharmacol , vol.44 , pp. 215-223
    • Shadle, C.R.1    Lee, Y.2    Majumdar, A.K.3
  • 25
    • 11144247021 scopus 로고    scopus 로고
    • Aprepitant: a novel antiemetic for chemotherapy-induced nausea and vomiting
    • Massaro AM, Lenz KL. Aprepitant: a novel antiemetic for chemotherapy-induced nausea and vomiting. Ann Pharmacother 2005; 39: 77-85.
    • (2005) Ann Pharmacother , vol.39 , pp. 77-85
    • Massaro, A.M.1    Lenz, K.L.2
  • 26
    • 0037757975 scopus 로고    scopus 로고
    • Effects of the neurokinin1 receptor antagonist aprepitant on the pharmacokinetics of dexamethasone and methylprednisolone
    • McCrea JB, Majumdar AK, Goldberg MR et al. Effects of the neurokinin1 receptor antagonist aprepitant on the pharmacokinetics of dexamethasone and methylprednisolone. Clin Pharmacol Ther 2003; 74: 17-24.
    • (2003) Clin Pharmacol Ther , vol.74 , pp. 17-24
    • McCrea, J.B.1    Majumdar, A.K.2    Goldberg, M.R.3
  • 27
    • 1842790093 scopus 로고    scopus 로고
    • Aprepitant: a review of its use in the prevention of chemotherapy-induced nausea and vomiting
    • Dando TM, Perry CM. Aprepitant: a review of its use in the prevention of chemotherapy-induced nausea and vomiting. Drugs 2004; 64: 777-794.
    • (2004) Drugs , vol.64 , pp. 777-794
    • Dando, T.M.1    Perry, C.M.2
  • 28
    • 21044452727 scopus 로고    scopus 로고
    • Lack of effect of aprepitant on the pharmacokinetics of docetaxel in cancer patients
    • Nygren P, Hande K, Petty KJ et al. Lack of effect of aprepitant on the pharmacokinetics of docetaxel in cancer patients. Cancer Chemother Pharmacol 2005; 55: 609-616.
    • (2005) Cancer Chemother Pharmacol , vol.55 , pp. 609-616
    • Nygren, P.1    Hande, K.2    Petty, K.J.3
  • 29
    • 22344440053 scopus 로고    scopus 로고
    • Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism
    • de Jonge M, Huitema A, Holtkamp M et al. Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism. Cancer Chemother Pharmacol 2005; 56: 370-378.
    • (2005) Cancer Chemother Pharmacol , vol.56 , pp. 370-378
    • de Jonge, M.1    Huitema, A.2    Holtkamp, M.3
  • 30
    • 33847262912 scopus 로고    scopus 로고
    • Antiemetic activity of corticosteroids in patients receiving cancer chemotherapy: dosing, efficacy, and tolerability analysis
    • Grunberg SM. Antiemetic activity of corticosteroids in patients receiving cancer chemotherapy: dosing, efficacy, and tolerability analysis. Ann Oncol 2007; 18: 233-240.
    • (2007) Ann Oncol , vol.18 , pp. 233-240
    • Grunberg, S.M.1
  • 31
    • 33645738248 scopus 로고    scopus 로고
    • Side effects associated with the use of dexamethasone for prophylaxis of delayed emesis after moderately emetogenic chemotherapy
    • Vardy J, Chiew KS, Galica J et al. Side effects associated with the use of dexamethasone for prophylaxis of delayed emesis after moderately emetogenic chemotherapy. Br J Cancer 2006; 94: 1011-1015.
    • (2006) Br J Cancer , vol.94 , pp. 1011-1015
    • Vardy, J.1    Chiew, K.S.2    Galica, J.3
  • 32
    • 77953349334 scopus 로고    scopus 로고
    • Double-blind, randomised, controlled study of the efficacy and tolerability of palonosetron plus dexamethasone for 1 day with or without dexamethasone on days 2 and 3 in the prevention of nausea and vomiting induced by moderately emetogenic chemotherapy
    • Aapro M, Fabi A, Nole F et al. Double-blind, randomised, controlled study of the efficacy and tolerability of palonosetron plus dexamethasone for 1 day with or without dexamethasone on days 2 and 3 in the prevention of nausea and vomiting induced by moderately emetogenic chemotherapy. Ann Oncol 2010; 21: 1083-1088.
    • (2010) Ann Oncol , vol.21 , pp. 1083-1088
    • Aapro, M.1    Fabi, A.2    Nole, F.3
  • 33
    • 64449084071 scopus 로고    scopus 로고
    • Effectiveness of a single-day three-drug regimen of dexamethasone, palonosetron, and aprepitant for the prevention of acute and delayed nausea and vomiting caused by moderately emetogenic chemotherapy
    • Grunberg SM, Dugan M, Muss H et al. Effectiveness of a single-day three-drug regimen of dexamethasone, palonosetron, and aprepitant for the prevention of acute and delayed nausea and vomiting caused by moderately emetogenic chemotherapy. Support Care Cancer 2009; 17: 589-594.
    • (2009) Support Care Cancer , vol.17 , pp. 589-594
    • Grunberg, S.M.1    Dugan, M.2    Muss, H.3
  • 34
    • 0024515648 scopus 로고
    • Controlling delayed vomiting: double-blind, randomized trial comparing placebo, dexamethasone alone, and metoclopramide plus dexamethasone in patients receiving cisplatin
    • Kris MG, Gralla RJ, Tyson LB et al. Controlling delayed vomiting: double-blind, randomized trial comparing placebo, dexamethasone alone, and metoclopramide plus dexamethasone in patients receiving cisplatin. J Clin Oncol 1989; 7: 108-114.
    • (1989) J Clin Oncol , vol.7 , pp. 108-114
    • Kris, M.G.1    Gralla, R.J.2    Tyson, L.B.3
  • 35
    • 0026741005 scopus 로고
    • Comparison of three protracted antiemetic regimens for the control of delayed emesis in cisplatin-treated patients
    • Moreno I, Rosell R, Abad A et al. Comparison of three protracted antiemetic regimens for the control of delayed emesis in cisplatin-treated patients. Eur J Cancer 1992; 28A: 1344-1347.
    • (1992) Eur J Cancer , vol.28 A , pp. 1344-1347
    • Moreno, I.1    Rosell, R.2    Abad, A.3
  • 36
    • 0031026404 scopus 로고    scopus 로고
    • The Italian Group for Antiemetic Research
    • Ondansetron versus metoclopramide, both combined with dexamethasone, in the prevention of cisplatin-induced delayed emesis
    • Ondansetron versus metoclopramide, both combined with dexamethasone, in the prevention of cisplatin-induced delayed emesis. The Italian Group for Antiemetic Research. J Clin Oncol 1997; 15: 124-130.
    • (1997) J Clin Oncol , vol.15 , pp. 124-130
  • 37
    • 0037294667 scopus 로고    scopus 로고
    • A randomized double-blind trial to compare the clinical efficacy of granisetron with metoclopramide, both combined with dexamethasone in the prophylaxis of chemotherapy-induced delayed emesis
    • Aapro MS, Thuerlimann B, Sessa C et al. A randomized double-blind trial to compare the clinical efficacy of granisetron with metoclopramide, both combined with dexamethasone in the prophylaxis of chemotherapy-induced delayed emesis. Ann Oncol 2003; 14: 291-297.
    • (2003) Ann Oncol , vol.14 , pp. 291-297
    • Aapro, M.S.1    Thuerlimann, B.2    Sessa, C.3
  • 38
    • 0035822323 scopus 로고    scopus 로고
    • Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review
    • Tramer MR, Carroll D, Campbell FA et al. Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review. BMJ 2001; 323: 16-21.
    • (2001) BMJ , vol.323 , pp. 16-21
    • Tramer, M.R.1    Carroll, D.2    Campbell, F.A.3
  • 39
    • 0029835209 scopus 로고    scopus 로고
    • Quality of life studies in chemotherapy-induced emesis
    • Osoba D, Zee B, Warr D et al. Quality of life studies in chemotherapy-induced emesis. Oncology 1996; 53 (Suppl 1): 92-95.
    • (1996) Oncology , vol.53 , Issue.SUPPL 1 , pp. 92-95
    • Osoba, D.1    Zee, B.2    Warr, D.3
  • 40
    • 15444340358 scopus 로고    scopus 로고
    • Efficacy of intravenous granisetron to control nausea and vomiting during multiple cycles of cisplatin-based chemotherapy
    • Ritter HJ, Gralla R, Hall S et al. Efficacy of intravenous granisetron to control nausea and vomiting during multiple cycles of cisplatin-based chemotherapy. Cancer Invest 1998; 16: 87-93.
    • (1998) Cancer Invest , vol.16 , pp. 87-93
    • Ritter, H.J.1    Gralla, R.2    Hall, S.3
  • 41
    • 70649090118 scopus 로고    scopus 로고
    • Palonosetron triggers 5-HT(3) receptor internalization and causes prolonged inhibition of receptor function
    • Rojas C, Thomas AG, Alt J et al. Palonosetron triggers 5-HT(3) receptor internalization and causes prolonged inhibition of receptor function. Eur J Pharmacol 2010; 626: 193-199.
    • (2010) Eur J Pharmacol , vol.626 , pp. 193-199
    • Rojas, C.1    Thomas, A.G.2    Alt, J.3
  • 42
    • 33748749890 scopus 로고    scopus 로고
    • A phase III, double-blind, randomized trial of palonosetron compared with ondansetron in preventing chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy
    • Aapro MS, Grunberg SM, Manikhas GM et al. A phase III, double-blind, randomized trial of palonosetron compared with ondansetron in preventing chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy. Ann Oncol 2006; 17: 1441-1449.
    • (2006) Ann Oncol , vol.17 , pp. 1441-1449
    • Aapro, M.S.1    Grunberg, S.M.2    Manikhas, G.M.3
  • 43
    • 10744219621 scopus 로고    scopus 로고
    • Palonosetron improves prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy: results of a double-blind randomized phase III trial comparing single doses of palonosetron with ondansetron
    • Gralla R, Lichinitser M, Van Der Vegt S et al. Palonosetron improves prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy: results of a double-blind randomized phase III trial comparing single doses of palonosetron with ondansetron. Ann Oncol 2003; 14: 1570-1577.
    • (2003) Ann Oncol , vol.14 , pp. 1570-1577
    • Gralla, R.1    Lichinitser, M.2    Van Der Vegt, S.3
  • 44
    • 0344412945 scopus 로고    scopus 로고
    • Improved prevention of moderately emetogenic chemotherapy-induced nausea and vomiting with palonosetron, a pharmacologically novel 5-HT3 receptor antagonist: results of a phase III, single-dose trial versus dolasetron
    • Eisenberg P, Figueroa-Vadillo J, Zamora R et al. Improved prevention of moderately emetogenic chemotherapy-induced nausea and vomiting with palonosetron, a pharmacologically novel 5-HT3 receptor antagonist: results of a phase III, single-dose trial versus dolasetron. Cancer 2003; 98: 2473-2482.
    • (2003) Cancer , vol.98 , pp. 2473-2482
    • Eisenberg, P.1    Figueroa-Vadillo, J.2    Zamora, R.3
  • 45
    • 58749100277 scopus 로고    scopus 로고
    • Palonosetron plus dexamethasone versus granisetron plus dexamethasone for prevention of nausea and vomiting during chemotherapy: a double-blind, double-dummy, randomised, comparative phase III trial
    • Saito M, Aogi K, Sekine I et al. Palonosetron plus dexamethasone versus granisetron plus dexamethasone for prevention of nausea and vomiting during chemotherapy: a double-blind, double-dummy, randomised, comparative phase III trial. Lancet Oncol 2009; 10: 115-124.
    • (2009) Lancet Oncol , vol.10 , pp. 115-124
    • Saito, M.1    Aogi, K.2    Sekine, I.3
  • 46
    • 78650372131 scopus 로고    scopus 로고
    • Palonosetron (PALO) versus granisetron (GRAN), both combined with dexamethasone (DEX) in preventing chemotherapy-induced nausea and vomiting (CINV) associated with cisplatin- or anthracycline plus cyclophosphamide-based regimens: results of a phase III trial in Japanese patients
    • (Abstr 20749)
    • Sekine I, Saito M, Aogi K et al. Palonosetron (PALO) versus granisetron (GRAN), both combined with dexamethasone (DEX) in preventing chemotherapy-induced nausea and vomiting (CINV) associated with cisplatin- or anthracycline plus cyclophosphamide-based regimens: results of a phase III trial in Japanese patients. J Clin Oncol 2008; 26: (Abstr 20749).
    • (2008) J Clin Oncol , vol.26
    • Sekine, I.1    Saito, M.2    Aogi, K.3
  • 47
    • 35348818158 scopus 로고    scopus 로고
    • Palonosetron plus dexamethasone for prevention of chemotherapy-induced nausea and vomiting in patients receiving multiple-day cisplatin chemotherapy for germ cell cancer
    • Einhorn LH, Brames MJ, Dreicer R et al. Palonosetron plus dexamethasone for prevention of chemotherapy-induced nausea and vomiting in patients receiving multiple-day cisplatin chemotherapy for germ cell cancer. Support Care Cancer 2007; 15: 1293-1300.
    • (2007) Support Care Cancer , vol.15 , pp. 1293-1300
    • Einhorn, L.H.1    Brames, M.J.2    Dreicer, R.3
  • 48
    • 77952480785 scopus 로고    scopus 로고
    • Aprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with a broad range of moderately emetogenic chemotherapies and tumor types: a randomized, doubleblind study
    • Rapoport BL, Jordan K, Boice JA et al. Aprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with a broad range of moderately emetogenic chemotherapies and tumor types: a randomized, doubleblind study. Support Care Cancer 2010; 18: 423-431.
    • (2010) Support Care Cancer , vol.18 , pp. 423-431
    • Rapoport, B.L.1    Jordan, K.2    Boice, J.A.3
  • 49
    • 64449083250 scopus 로고    scopus 로고
    • Safety and efficacy of a triple antiemetic combination with the NK-1 antagonist aprepitant in highly and moderately emetogenic multiple-day chemotherapy
    • Jordan K, Kinitz I, Voigt W et al. Safety and efficacy of a triple antiemetic combination with the NK-1 antagonist aprepitant in highly and moderately emetogenic multiple-day chemotherapy. Eur J Cancer 2009; 45: 1184-1187.
    • (2009) Eur J Cancer , vol.45 , pp. 1184-1187
    • Jordan, K.1    Kinitz, I.2    Voigt, W.3
  • 50
    • 0034796398 scopus 로고    scopus 로고
    • Randomized open-label trial of dolasetron for the control of nausea and vomiting associated with high-dose chemotherapy with hematopoietic stem cell transplantation
    • Bubalo J, Seelig F, Karbowicz S, Maziarz RT. Randomized open-label trial of dolasetron for the control of nausea and vomiting associated with high-dose chemotherapy with hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2001; 7: 439-445.
    • (2001) Biol Blood Marrow Transplant , vol.7 , pp. 439-445
    • Bubalo, J.1    Seelig, F.2    Karbowicz, S.3    Maziarz, R.T.4
  • 51
    • 78650413378 scopus 로고    scopus 로고
    • Prolonged administration of aprepitant does not increase toxicity in patients undergoing high dose chemotherapy and autologous stem cell transplant
    • Junagadhwalla M, Chilton J, Gentile T et al. Prolonged administration of aprepitant does not increase toxicity in patients undergoing high dose chemotherapy and autologous stem cell transplant. Blood 2005; 106.
    • (2005) Blood , pp. 106
    • Junagadhwalla, M.1    Chilton, J.2    Gentile, T.3
  • 52
    • 78650317204 scopus 로고    scopus 로고
    • Evaluation of aprepitant for treatment of acute and delayed chemotherapy-induced nausea and vomiting in patients undergoing autologous stem cell transplantation
    • Barnet C, Oholendt M, Popat U et al. Evaluation of aprepitant for treatment of acute and delayed chemotherapy-induced nausea and vomiting in patients undergoing autologous stem cell transplantation. Blood 2004; 104.
    • (2004) Blood , pp. 104
    • Barnet, C.1    Oholendt, M.2    Popat, U.3
  • 53
    • 78650330460 scopus 로고    scopus 로고
    • Aprepitant in the prevention of acute and delayed nausea and vomiting following haematopoietic stem cell transplantation: a pilot study
    • Szer JGA, Roberts AW et al. Aprepitant in the prevention of acute and delayed nausea and vomiting following haematopoietic stem cell transplantation: a pilot study. Bone Marrow Trans 2006; 37: 112.
    • (2006) Bone Marrow Trans , vol.37 , pp. 112
    • Szer, J.G.A.1    Roberts, A.W.2
  • 54
    • 85055552715 scopus 로고    scopus 로고
    • A prospective, randomized phase III trial of oral ondansetron and dexamethasone alone vs. oral ondansetron, dexamethasone and the NK-1 inhibitor, aprepitant (Emend) for the prevention of nausea and vomiting associated with highly emetogenic preparative regimens prior to stem cell transplantation
    • (Abstr 2267)
    • Stiff P, Fox-Geimann MP, Kiley K et al. A prospective, randomized phase III trial of oral ondansetron and dexamethasone alone vs. oral ondansetron, dexamethasone and the NK-1 inhibitor, aprepitant (Emend) for the prevention of nausea and vomiting associated with highly emetogenic preparative regimens prior to stem cell transplantation. Blood 2009; 114: (Abstr 2267).
    • (2009) Blood , vol.114
    • Stiff, P.1    Fox-Geimann, M.P.2    Kiley, K.3
  • 55
    • 77749298960 scopus 로고    scopus 로고
    • Efficacy of aprepitant in patients receiving high-dose chemotherapy with hematopoietic stem cell support
    • Paul B, Trovato JA, Thompson J et al. Efficacy of aprepitant in patients receiving high-dose chemotherapy with hematopoietic stem cell support. J Oncol Pharm Pract 2010; 1: 45-51.
    • (2010) J Oncol Pharm Pract , vol.1 , pp. 45-51
    • Paul, B.1    Trovato, J.A.2    Thompson, J.3
  • 56
    • 78650341934 scopus 로고    scopus 로고
    • Phase III randomized double-blind study of single-dose fosaprepitant for prevention of cisplatin-induced nausea and vomiting (CINV)
    • (Abstr 9021)
    • Grunberg S, Chua DT, Roila F, Herrstedt J. Phase III randomized double-blind study of single-dose fosaprepitant for prevention of cisplatin-induced nausea and vomiting (CINV). J Clin Oncol 2010; 28: (Abstr 9021).
    • (2010) J Clin Oncol , vol.28
    • Grunberg, S.1    Chua, D.T.2    Roila, F.3    Herrstedt, J.4
  • 57
    • 50049112201 scopus 로고    scopus 로고
    • Complete rescue from established emesis by the NK-1 receptor antagonist, casopitant mesylate, in cisplatin-induced delayed emesis in the ferret
    • (Abstr 18601)
    • King AG. Complete rescue from established emesis by the NK-1 receptor antagonist, casopitant mesylate, in cisplatin-induced delayed emesis in the ferret. J Clin Oncol 2006; 24: (Abstr 18601).
    • (2006) J Clin Oncol , vol.24
    • King, A.G.1
  • 58
    • 66149139289 scopus 로고    scopus 로고
    • Efficacy and safety of casopitant mesylate, a neurokinin 1 (NK1)-receptor antagonist, in prevention of chemotherapy-induced nausea and vomiting in patients receiving cisplatin-based highly emetogenic chemotherapy: a randomised, double-blind, placebocontrolled trial
    • Grunberg SM, Rolski J, Strausz J et al. Efficacy and safety of casopitant mesylate, a neurokinin 1 (NK1)-receptor antagonist, in prevention of chemotherapy-induced nausea and vomiting in patients receiving cisplatin-based highly emetogenic chemotherapy: a randomised, double-blind, placebocontrolled trial. Lancet Oncol 2009; 6: 549-558.
    • (2009) Lancet Oncol , vol.6 , pp. 549-558
    • Grunberg, S.M.1    Rolski, J.2    Strausz, J.3
  • 59
    • 73949158930 scopus 로고    scopus 로고
    • Casopitant, a novel neurokinin-1 receptor antagonist, for the prevention of chemotherapy-induced nausea and vomiting: phase III trial results in patients receiving moderately emetogenic chemotherapy
    • Herrstedt J, Apornwirat W, Shaharyar A et al. Casopitant, a novel neurokinin-1 receptor antagonist, for the prevention of chemotherapy-induced nausea and vomiting: phase III trial results in patients receiving moderately emetogenic chemotherapy. J Clin Oncol 2009; 27: 5363-5369.
    • (2009) J Clin Oncol , vol.27 , pp. 5363-5369
    • Herrstedt, J.1    Apornwirat, W.2    Shaharyar, A.3
  • 60
    • 46749132406 scopus 로고    scopus 로고
    • Casopitant, a neurokinin-1 receptor antagonist with anti-emetic and anti-nausea activities
    • Navari RM. Casopitant, a neurokinin-1 receptor antagonist with anti-emetic and anti-nausea activities. Curr Opin Investig Drugs 2008; 9: 774-785.
    • (2008) Curr Opin Investig Drugs , vol.9 , pp. 774-785
    • Navari, R.M.1
  • 61
    • 71649109972 scopus 로고    scopus 로고
    • Effect of casopitant, a novel neurokinin-1 (NK-1) receptor antagonist for prevention of chemotherapy induced nausea and vomiting (CINV), on the pharmacokinetics (PK) and pharmacodynamics (PD) of steady-state warfarin
    • (Abstr 20587)
    • Blum R, Adams LM, Johnson BM et al. Effect of casopitant, a novel neurokinin-1 (NK-1) receptor antagonist for prevention of chemotherapy induced nausea and vomiting (CINV), on the pharmacokinetics (PK) and pharmacodynamics (PD) of steady-state warfarin. J Clin Oncol 2008; 26: (Abstr 20587).
    • (2008) J Clin Oncol , vol.26
    • Blum, R.1    Adams, L.M.2    Johnson, B.M.3
  • 62
    • 0033522430 scopus 로고    scopus 로고
    • Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitro
    • Bymaster FP, Nelson DL, DeLapp NW et al. Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitro. Schizophr Res 1999; 37: 107-122.
    • (1999) Schizophr Res , vol.37 , pp. 107-122
    • Bymaster, F.P.1    Nelson, D.L.2    DeLapp, N.W.3
  • 63
    • 0032967875 scopus 로고    scopus 로고
    • The in vivo effects of olanzapine and other antipsychotic agents on receptor occupancy and antagonism of dopamine D1, D2, D3
    • Zhang W, Bymaster FP. The in vivo effects of olanzapine and other antipsychotic agents on receptor occupancy and antagonism of dopamine D1, D2, D3, 5HT2A and muscarinic receptors. Psychopharmacology (Berl) 1999; 141: 267-278.
    • (1999) 5HT2A and muscarinic receptors. Psychopharmacology (Berl) , vol.141 , pp. 267-278
    • Zhang, W.1    Bymaster, F.P.2
  • 64
    • 34347369980 scopus 로고    scopus 로고
    • A phase II trial of olanzapine, dexamethasone, and palonosetron for the prevention of chemotherapy-induced nausea and vomiting: a Hoosier oncology group study
    • Navari RM, Einhorn LH, Loehrer PJ Sr et al. A phase II trial of olanzapine, dexamethasone, and palonosetron for the prevention of chemotherapy-induced nausea and vomiting: a Hoosier oncology group study. Support Care Cancer 2007; 15: 1285-1291.
    • (2007) Support Care Cancer , vol.15 , pp. 1285-1291
    • Navari, R.M.1    Einhorn, L.H.2    Loehrer Sr., P.J.3
  • 65
    • 4744339480 scopus 로고    scopus 로고
    • A phase I trial of olanzapine (Zyprexa) for the prevention of delayed emesis in cancer patients: a Hoosier Oncology Group study
    • Passik SD, Navari RM, Jung SH et al. A phase I trial of olanzapine (Zyprexa) for the prevention of delayed emesis in cancer patients: a Hoosier Oncology Group study. Cancer Invest 2004; 22: 383-388.
    • (2004) Cancer Invest , vol.22 , pp. 383-388
    • Passik, S.D.1    Navari, R.M.2    Jung, S.H.3
  • 66
    • 78650338238 scopus 로고    scopus 로고
    • Olanzapine versus Aprepitant for the prevention of chemotherapy induced nausea and vomiting (CINV): a randomized phase III trial
    • Navari R, Gray SE, Carr AC. Olanzapine versus Aprepitant for the prevention of chemotherapy induced nausea and vomiting (CINV): a randomized phase III trial. J Clin Oncol 2010; 28: # 9020.
    • (2010) J Clin Oncol , vol.28 , pp. 9020
    • Navari, R.1    Gray, S.E.2    Carr, A.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.