Infections in hematogical cancer patients: The contribution of systematic reviews and meta-analyses

Acta Haematologica

Volumn 125, Issue 1-2, 2010, Pages 80-90

  Paul, Mical ^a   Gafter Gvili, Anat ^a   Goldberg, Elad ^a   Yahav, Dafna ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Antibiotics; Antifungals; Antivirals; Infection control; Meta analysis; Prophylaxis; Systematic review

Indexed keywords

ACICLOVIR; ANTIFUNGAL AGENT; BENZIMIDAVIR; CARBENICILLIN; CEFALOTIN; CEFEPIME; CEFTAZIDIME; COTRIMOXAZOLE; GANCICLOVIR; GENTAMICIN; IMIPENEM; IMMUNOGLOBULIN; LEVOFLOXACIN; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM;

ANTIBIOTIC RESISTANCE; ARTICLE; CANCER PATIENT; COMBINATION CHEMOTHERAPY; CYTOMEGALOVIRUS INFECTION; DRUG INDICATION; FEBRILE NEUTROPENIA; GRAM NEGATIVE INFECTION; HEMATOLOGIC MALIGNANCY; HUMAN; INFECTION; INFECTION CONTROL; INTERSTITIAL PNEUMONIA; META ANALYSIS (TOPIC); MONOTHERAPY; MYCOSIS; NEUTROPENIA; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SYSTEMATIC REVIEW (TOPIC);

HEMATOLOGIC NEOPLASMS; HUMANS; INFECTION; META-ANALYSIS AS TOPIC; NEUTROPENIA; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REVIEW LITERATURE AS TOPIC; TREATMENT OUTCOME;

EID: 78650369326     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000318900     Document Type: Article

References (34)

1. Pizzo PA, Hathorn JW, Hiemenz J, Browne M, Commers J, Cotton D, Gress J, Longo D, Marshall D, McKnight J, Rubin M, Skelton J, Thaler M, Wesley R: A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia. N Engl J Med 1986; 315: 552-558.
2. Giamarellou H: Aminoglycosides plus betalactams against gram-negative organisms. Evaluation of in vitro synergy and chemical interactions. Am J Med 1986; 80: 126-137.
3. Klastersky J, Meunier-Carpentier F, Prevost JM, Staquet M: Synergism between amikacin and cefazolin against Klebsiella: in vitro studies and effect on the bactericidal activity of serum. J Infect Dis 1976; 134: 271-276.
4. Klastersky J, Zinner SH: Synergistic combinations of antibiotics in gram-negative bacillary infections. Rev Infect Dis 1982; 4: 294-301.
5. Paul M, Soares-Weiser K, Grozinsky S, Leibovici L: Beta-lactam versus beta-lactamaminoglycoside combination therapy in cancer patients with neutropaenia. Cochrane Database Syst Rev 2003; 3:CD003038.
6. Paul M, Soares-Weiser K, Leibovici L: Beta lactam monotherapy versus beta lactamaminoglycoside combination therapy for fever with neutropenia: systematic review and meta-analysis. BMJ 2003; 326: 1111.
7. Yahav D, Gafter-Gvili A, Muchtar E, Skalsky K, Kariv G, Yeshurun M, Leibovici L, Paul M: Antiviral prophylaxis in haematological patients: systematic review and meta-analysis. Eur J Cancer 2009; 45: 3131-3148.
8. Gafter-Gvili A, Fraser A, Paul M, Leibovici L: Meta-analysis: antibiotic prophylaxis reduces mortality in neutropenic patients. Ann Intern Med 2005; 142: 979-995.
9. Gafter-Gvili A, Fraser A, Paul M, van de Wetering M, Kremer L, Leibovici L: Antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemotherapy. Cochrane Database Syst Rev 2005; 4:CD004386.
10. Gafter-Gvili A, Paul M, Fraser A, Leibovici L: Effect of quinolone prophylaxis in afebrile neutropenic patients on microbial resistance: systematic review and meta-analysis. J Antimicrob Chemother 2007; 59: 5-22.
11. Hughes WT, Armstrong D, Bodey GP, Bow EJ, Brown AE, Calandra T, Feld R, Pizzo PA, Rolston KV, Shenep JL, Young LS: 2002 guidelines for the use of antimicrobial agents in neutropenic patients with cancer. Clin Infect Dis 2002; 34: 730-751.
12. Bucaneve G, Castagnola E, Viscoli C, Leibovici L, Menichetti F: Quinolone prophylaxis for bacterial infections in afebrile high risk neutropenic patients. Eur J Cancer 2007; 5: 5-12.
13. Paul M, Yahav D, Fraser A, Leibovici L: Empirical antibiotic monotherapy for febrile neutropenia: systematic review and metaanalysis of randomized controlled trials. J Antimicrob Chemother 2006; 57: 176-189. (Pubitemid 43160156)
14. Paul M, Yahav D, Fraser A, Leibovici L: Antipseudomonal beta-lactam monotherapy for the initial, empirical, treatment of febrile neutropenia: comparison of beta-lactams (intervention protocol, full updated review to be published). Cochrane Database Syst Rev 2007; 4:CD005197.
15. Yahav D, Paul M, Fraser A, Sarid N, Leibovici L: Efficacy and safety of cefepime: a systematic review and meta-analysis. Lancet Infect Dis 2007; 7: 338-348.
16. US Food and Drug Administration: Information for Healthcare Professionals: Cefepime (marketed as Maxipime). 2009. http://www.fda.gov/Drugs/ DrugSafety/ PostmarketDrugSafetyInformationforPatientsandProviders/ DrugSafetyInformationforHeathcareProfessionals/ ucm167254. htm.
17. Paul M, Borok S, Fraser A, Vidal L, Cohen M, Leibovici L: Additional anti-Gram-positive antibiotic treatment for febrile neutropenic cancer patients. Cochrane Database Syst Rev 2005; 3:CD003914.
18. Paul M, Borok S, Fraser A, Vidal L, Leibovici L: Empirical antibiotics against Gram-positive infections for febrile neutropenia: systematic review and meta-analysis of randomized controlled trials. J Antimicrob Chemother 2005; 55: 436-444.
19. Robenshtok E, Gafter-Gvili A, Goldberg E, Weinberger M, Yeshurun M, Leibovici L, Paul M: Antifungal prophylaxis in cancer patients after chemotherapy or hematopoietic stem-cell transplantation: systematic review and meta-analysis. J Clin Oncol 2007; 25: 5471-5489.
20. Goldberg E, Gafter-Gvili A, Robenshtok E, Leibovici L, Paul M: Empirical antifungal therapy for patients with neutropenia and persistent fever: systematic review and metaanalysis. Eur J Cancer 2008; 44: 2192-2203.
21. Raanani P, Gafter-Gvili A, Paul M, Ben-Bassat I, Leibovici L, Shpilberg O: Immunoglobulin prophylaxis in hematopoietic stem cell transplantation: systematic review and meta- analysis. J Clin Oncol 2009; 27: 770-781.
22. Raanani P, Gafter-Gvili A, Paul M, Ben- Bassat I, Leibovici L, Shpilberg O: Immunoglobulin prophylaxis in hematological malignancies and hematopoietic stem cell transplantation. Cochrane Database Syst Rev 2008; 4:CD006501.
23. Leibovici L, Paul M, Cullen M, Bucaneve G, Gafter-Gvili A, Fraser A, Kern WV: Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions. Cancer 2006; 107: 1743-1751.
24. Bucaneve G, Micozzi A, Menichetti F, Martino P, Dionisi MS, Martinelli G, Allione B, D'Antonio D, Buelli M, Nosari AM, Cilloni D, Zuffa E, Cantaffa R, Specchia G, Amadori S, Fabbiano F, Deliliers GL, Lauria F, Foà R, Del Favero A, Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) Infection Program: Levofloxacin to prevent bacterial infection in patients with cancer and neutropenia. N Engl J Med 2005; 353: 977-987.
25. Cullen M, Steven N, Billingham L, Gaunt C, Hastings M, Simmonds P, Stuart N, Rea D, Bower M, Fernando I, Huddart R, Gollins S, Stanley A; Simple Investigation in Neutropenic Individuals of the Frequency of Infection after Chemotherapy +/- Antibiotic in a Number of Tumours (SIGNIFICANT) Trial Group: Antibacterial prophylaxis after chemotherapy for solid tumors and lymphomas. N Engl J Med 2005; 353: 988-998.
26. Vidal L, Paul M, Ben dor I, Soares-Weiser K, Leibovici L: Oral versus intravenous antibiotic treatment for febrile neutropenia in cancer patients: a systematic review and metaanalysis of randomized trials. J Antimicrob Chemother 2004; 54: 29-37.
27. Vidal L, Paul M, Ben-Dor I, Pokroy E, Soares- Weiser K, Leibovici L: Oral versus intravenous antibiotic treatment for febrile neutropenia in cancer patients. Cochrane Database Syst Rev 2004; 4:CD003992.
28. Schlesinger A, Paul M, Gafter-Gvili A, Rubinovitch B, Leibovici L: Infection-control interventions for cancer patients after chemotherapy: a systematic review and metaanalysis. Lancet Infect Dis 2009; 9: 97-107.
29. Raanani P, Gafter-Gvili A, Paul M, Ben-Bassat I, Leibovici L, Shpilberg O: Immunoglobulin prophylaxis in chronic lymphocytic leukemia and multiple myeloma: systematic review and meta-analysis. Leuk Lymphoma 2009; 50: 764-772.
30. Consensus on IVIG. Lancet 1990; 336: 470-472.
31. Green H, Paul M, Vidal L, Leibovici L: Prophylaxis for Pneumocystis pneumonia (PCP) in non-HIV immunocompromised patients. Cochrane Database Syst Rev 2007; 3:CD005590.
32. Green H, Paul M, Vidal L, Leibovici L: Prophylaxis of Pneumocystis pneumonia in immunocompromised non-HIV-infected patients: systematic review and meta-analysis of randomized controlled trials. Mayo Clin Proc 2007; 82: 1052-1059.
33. Paul M, Leibovici L: Systematic reviews and meta-analysis of febrile neutropenia. Mayo Clin Proc 2005; 80: 1122-1125.
34. Higgins JPT, Green S (eds): Cochrane Handbook for Systematic Reviews of Interventions, version 5.0.2 (updated September 2009). The Cochrane Collaboration, 2008. www.cochrane-handbook.org.