메뉴 건너뛰기




Volumn 151, Issue 51, 2010, Pages 2099-2104

First decade of post-genomic era. Hopes, disappointments, new answers;Az elso posztgenom évtized az orvostudományban

Author keywords

competences; education; epigenetics; genetics; genomics; missing heritability

Indexed keywords

ARTICLE; GENETICS; GENOMICS; GENOTYPE ENVIRONMENT INTERACTION; HEALTH CARE DELIVERY; HOPE; HUMAN; HUMAN GENOME; MEDICAL RESEARCH; PROFESSIONAL COMPETENCE;

EID: 78650362446     PISSN: 00306002     EISSN: 17886120     Source Type: Journal    
DOI: 10.1556/OH.2010.29014     Document Type: Article
Times cited : (4)

References (27)
  • 1
    • 77950412216 scopus 로고    scopus 로고
    • Editorial: The human genome at ten
    • Editorial: The human genome at ten. Nature, 2010, 464, 649-650.
    • (2010) Nature , vol.464 , pp. 649-650
  • 2
    • 77953950197 scopus 로고    scopus 로고
    • Human genome at ten: Science after the sequence
    • Butler, D.: Human genome at ten: science after the sequence. Nature, 2010, 465, 1000-1001.
    • (2010) Nature , vol.465 , pp. 1000-1001
    • Butler, D.1
  • 3
    • 77950398306 scopus 로고    scopus 로고
    • Human genome at ten: Life is complicated
    • Hayden, C. E.: Human genome at ten: life is complicated. Nature, 2010, 464 664-667.
    • (2010) Nature , vol.464 , pp. 664-667
    • Hayden, C.E.1
  • 4
    • 77952768072 scopus 로고    scopus 로고
    • Ten years on-the human genome and medicine
    • Varmus, H.: Ten years on-the human genome and medicine. New Engl. J. Med., 2010, 362, 2028-2029.
    • (2010) New Engl. J. Med. , vol.362 , pp. 2028-2029
    • Varmus, H.1
  • 5
    • 77949772292 scopus 로고    scopus 로고
    • Gene-environment-wide association studies: Emerging approaches
    • Thomas, D.: Gene-environment-wide association studies: emerging approaches. Nature Rev. Genet., 2010, 11, 259-272.
    • (2010) Nature Rev. Genet. , vol.11 , pp. 259-272
    • Thomas, D.1
  • 6
    • 70349956433 scopus 로고    scopus 로고
    • És mtsai: Finding the missing heritability of complex diseases
    • Manolio, T. A., Collins, F. S., Cox, N. J. és mtsai: Finding the missing heritability of complex diseases. Nature, 2009, 461, 747-753.
    • (2009) Nature , vol.461 , pp. 747-753
    • Manolio, T.A.1    Collins, F.S.2    Cox, N.J.3
  • 7
    • 70349326221 scopus 로고    scopus 로고
    • Epigenetic inheritance and the missing heritability problem
    • Slatkin, M.: Epigenetic inheritance and the missing heritability problem. Genetics, 2009, 182, 845-850.
    • (2009) Genetics , vol.182 , pp. 845-850
    • Slatkin, M.1
  • 8
    • 77954891473 scopus 로고    scopus 로고
    • GWAS: Heritability missing in action?
    • Clarke, A, Cooper, D. N.: GWAS: heritability missing in action? Eur. J. Hum. Genet., 2010, 18, 859-861.
    • (2010) Eur. J. Hum. Genet. , vol.18 , pp. 859-861
    • Clarke, A.1    Cooper, D.N.2
  • 9
    • 0038670579 scopus 로고    scopus 로고
    • The human phenome project
    • Freimer, N., Sabatti, C: The Human Phenome Project. Nature Genet., 2003, 34, 15-21.
    • (2003) Nature Genet. , vol.34 , pp. 15-21
    • Freimer, N.1    Sabatti, C.2
  • 10
    • 84954358609 scopus 로고    scopus 로고
    • És mtsai: The Human Phenome Ontology: A tool for annotating and analyzing human hereditary disease
    • Robinson, P. N., Köhler, S., Bauer, S. és mtsai: The Human Phenome Ontology: a tool for annotating and analyzing human hereditary disease. Am. J. Hum. Genet., 2008, 83, 610-615.
    • (2008) Am. J. Hum. Genet. , vol.83 , pp. 610-615
    • Robinson, P.N.1    Köhler, S.2    Bauer, S.3
  • 11
    • 0033168459 scopus 로고    scopus 로고
    • Medical and societal consequences of the Human Genome Project
    • Collins, F. S.: Medical and societal consequences of the Human Genome Project. New Eng. J. Med., 1999, 341, 28-37.
    • (1999) New Eng. J. Med. , vol.341 , pp. 28-37
    • Collins, F.S.1
  • 12
    • 17544403540 scopus 로고    scopus 로고
    • Funkcionális genomika: lehetségek remények posztgenomiális realizmus
    • Falus A, Szalai Cs., Tóth S.: Funkcionális genomika: lehetségek, remények, posztgenomiális realizmus. LAM, 2002, 12, 365-370.
    • (2002) LAM , vol.12 , pp. 365-370
    • Falus, A.1    Szalai, Cs.2    Tóth, S.3
  • 14
    • 33748653395 scopus 로고    scopus 로고
    • Medical genetics in the genomic medicine of the 21st Century
    • Epstein, C. J.: Medical genetics in the genomic medicine of the 21st Century Am. J. Hum. Genet., 2006, 79, 434-438.
    • (2006) Am. J. Hum. Genet. , vol.79 , pp. 434-438
    • Epstein, C.J.1
  • 15
    • 77957102435 scopus 로고    scopus 로고
    • The medical geneticist as expert in the transgenerational and developmental aspects of diseases
    • Kosztolányi G.Y., Cassiman, J-J.: The medical geneticist as expert in the transgenerational and developmental aspects of diseases. Eur. J. Hum. Genet., 2010, 18, 1075-1076.
    • (2010) Eur. J. Hum. Genet. , vol.18 , pp. 1075-1076
    • Kosztolányi, G.Y.1    Cassiman, J.-J.2
  • 16
    • 39749171775 scopus 로고    scopus 로고
    • Environmental epigenomics in human health and disease
    • Dolinoy, D. C, Jirtle, R. L.: Environmental epigenomics in human health and disease. Environ. Molec Mutagen., 2008, 49, 4-8.
    • (2008) Environ. Molec Mutagen. , vol.49 , pp. 4-8
    • Dolinoy, D.C.1    Jirtle, R.L.2
  • 17
    • 78650311943 scopus 로고    scopus 로고
    • A gyermekfejldés epigenetikája
    • Kosztolányi G.Y.: A gyermekfejl?dés epigenetikája. Magyar Tudomány, 2010, 171, 1083-1089.
    • (2010) Magyar Tudomány , vol.171 , pp. 1083-1089
    • Kosztolányi, G.Y.1
  • 19
    • 77349103259 scopus 로고    scopus 로고
    • Can our understanding of epigenetics assist with primary prevention of congenital defects?
    • Martinez-Frias, M. L.: Can our understanding of epigenetics assist with primary prevention of congenital defects? J. Med. Genet., 2010, 47, 73-80.
    • (2010) J. Med. Genet. , vol.47 , pp. 73-80
    • Martinez-Frias, M.L.1
  • 20
    • 70549104872 scopus 로고    scopus 로고
    • És mtsai: Dynamic DNA methylation programs persistent adverse effects of earlylife stress
    • Murgatroyd, C, Patchev, A. V., Wu, Y. H. és mtsai: Dynamic DNA methylation programs persistent adverse effects of earlylife stress. Nature Neurosci., 2009, 12, 1559-1566.
    • (2009) Nature Neurosci. , vol.12 , pp. 1559-1566
    • Murgatroyd, C.1    Patchev, A.V.2    Wu, Y.H.3
  • 21
    • 70450217879 scopus 로고    scopus 로고
    • És mtsai: Human DNA methylomes at base resolution show widespread epigenomic differences
    • Lister, R., Pelizzola, M., Dowen, R. H. és mtsai: Human DNA methylomes at base resolution show widespread epigenomic differences. Nature, 2009, 462, 315-322.
    • (2009) Nature , vol.462 , pp. 315-322
    • Lister, R.1    Pelizzola, M.2    Dowen, R.H.3
  • 22
    • 65249157050 scopus 로고    scopus 로고
    • Epigenetics, DNA methylation and chromatin modifying drugs
    • Szyf, M.: Epigenetics, DNA methylation and chromatin modifying drugs. Ann. Rev. Pharmacol. Toxicol., 2009, 49, 243-263.
    • (2009) Ann. Rev. Pharmacol. Toxicol. , vol.49 , pp. 243-263
    • Szyf, M.1
  • 23
    • 77953812272 scopus 로고    scopus 로고
    • Environmental epigenetics
    • Bollati, V, Baccarelli, A: Environmental epigenetics. Heredity, 2010, 105, 105-112.
    • (2010) Heredity , vol.105 , pp. 105-112
    • Bollati, V.1    Baccarelli, A.2
  • 24
    • 78650349457 scopus 로고    scopus 로고
    • A decade of progress and misunderstandings
    • 28 June
    • Pembrey, M.: A decade of progress and misunderstandings. BioNews, 2010, 564, 28 June
    • (2010) BioNews , pp. 564
    • Pembrey, M.1
  • 25
    • 78549241587 scopus 로고    scopus 로고
    • European Society of Human Genetics: Statement of the ESHG on the direct-to-consumer genetic testing for health-related purposes
    • Published online 25 August. 2010
    • European Society of Human Genetics: Statement of the ESHG on the direct-to-consumer genetic testing for health-related purposes. Eur. J. Hum. Genet., 2010, 18, 1271-1273. (Published online 25 August. 2010.)
    • (2010) Eur. J. Hum. Genet. , vol.18 , pp. 1271-1273
  • 26
    • 84873236907 scopus 로고    scopus 로고
    • Core competencies for genetic service delivery in Europe
    • www.eurogentest.org/professionals/education/Core competencies for genetic service delivery in Europe
  • 27
    • 0034776466 scopus 로고    scopus 로고
    • Genomic medicine: Who will practice it? A call to open arms
    • Guttmacher, A. E., Jenkins, J., Uhlmann, W. R.: Genomic medicine: who will practice it? A call to open arms. Am. J. Med. Genet., 2001, 106, 216-222.
    • (2001) Am. J. Med. Genet. , vol.106 , pp. 216-222
    • Guttmacher, A.E.1    Jenkins, J.2    Uhlmann, W.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.