Chloride homeostasis and GABA signaling in temporal lobe epilepsy

Epilepsia

Volumn 51, Issue SUPPL. 5, 2010, Pages 52-

  Kaila, Kai ^a   Miles, Richard ^b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b INSERM   (France)

Author keywords

Animal models; BDNF; Chloride co transporter; Human tissue; Inter ictal events; Pyramidal cells; Seizures

Indexed keywords

4 AMINOBUTYRIC ACID; CHLORIDE; POTASSIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER;

ARTICLE; CHLORIDE TRANSPORT; DEPOLARIZATION; DOWN REGULATION; EPILEPTIC DISCHARGE; EPILEPTOGENESIS; FOCAL EPILEPSY; HOMEOSTASIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SIGNAL TRANSDUCTION; TEMPORAL LOBE EPILEPSY;

EID: 78650361074     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2010.02838.x     Document Type: Article

References (4)

1. Blaesse P, Airaksinen MS, Rivera C, Kaila K,. (2009) Cation-chloride cotransporters and neuronal function. Neuron 61: 820-838.
2. Cohen I, Navarro V, Clemenceau S, Baulac M, Miles R,. (2002) On the origin of interictal activity in human temporal lobe epilepsy in vitro. Science 298: 1418-1421.
3. Huberfeld G, Wittner L, Clemenceau S, Baulac M, Kaila K, Miles R, Rivera C,. (2007) Perturbed chloride homeostasis and GABAergic signaling in human temporal lobe epilepsy. J Neurosci 27: 9866-9873.
4. - co-transporter KCC2 promotes GABAergic excitation in the mature rat hippocampus. J Physiol 588: 1527-1540.