Mesenchymal stem cells for acute lung injury: Preclinical evidence

Critical Care Medicine

Volumn 38, Issue 10 SUPPL., 2010, Pages

  Matthay, Michael A ^a   Goolaerts, Arnaud ^b   Howard, James P ^c   Lee, Jae Woo ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acute respiratory distress syndrome; Acute respiratory failure; Pulmonary edema; Sepsis

Indexed keywords

BLEOMYCIN; ENDOTOXIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; KERATINOCYTE GROWTH FACTOR; PROSTAGLANDIN E2; SMALL INTERFERING RNA;

ACUTE KIDNEY FAILURE; ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; CONFERENCE PAPER; CULTURE MEDIUM; HUMAN; HYPEROXIA; LUNG INJURY; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; SEPSIS;

EID: 78650345506     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181f1ff1d     Document Type: Conference Paper

References (29)

1. Brower RG, Morris A, MacIntryre N, et al: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000;342:1301-1308
2. Wiedemann HP, Wheeler AP, Bernard GR, et al: Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 2006;354:2564-2575
3. Calfee CS, Matthay MA: Nonventilatory treatments for acute lung injury and ARDS. Chest 2007;131:913-920
4. Rubenfeld GD, Caldwell E, Peabody E, et al: Incidence and outcomes of acute lung injury. N Engl J Med 2005;353:1685-1693
5. Cepkova M, Matthay MA: Pharmacotherapy of acute lung injury and the acute respiratory distress syndrome. J Intensive Care Med 2006;21:119-143
6. Krause DS, Theise ND, Collector MI, et al: Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 2001;105:369-377
7. Lee JW, Gupta N, Serikov V, et al: Potential application of mesenchymal stem cells in acute lung injury. Expert Opin Biol Ther 2009;9:1259-1270
8. Friedenstein AJ, Petrakova KV, Kurolesova AI, et al: Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissues. Transplantation 1968;6:230-247
9. Chan JL, Tang KC, Patel AP, et al: Antigenpresenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon-gamma. Blood 2006;107:4817-4824
10. Nauta AJ, Westerhuis G, Kruisselbrink AB, et al: Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting. Blood 2006;108:2114-2120
11. Stagg J: Immune regulation by mesenchymal stem cells: Two sides to the coin. Tissue Antigens 2007;69:1-9
12. Miyahara Y, Nagaya N, Kataoka M, et al: Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction. Nat Med 2006;12:459-465
13. Lee RH, Pulin AA, Seo MJ, et al: Intravenous hMSCss improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell 2009;5:54-63
14. Lee RH, Seo MJ, Reger RL, et al: Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice. Proc Nat Acad Sci U S A 2006;103:17438-17443
15. Parekkadan B, van Poll D, Suganuma K, et al: Mesenchymal stem cell-derived molecules reverse fulminant hepatic failure. PLoS One 2007;2:e941
16. Togel F, Hu Z, Weiss K, et al: Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol 2005;289:F31-F42 (Pubitemid 40863570)
17. Nemeth K, Leelahavanichkul A, Yuen PS, et al: Bone marrow stromal cells attenuate sepsis via prostaglandin E (2)-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat Med 2009;15:42-49
18. Ortiz LA, Gambelli F, McBride C, et al: Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects. Proc Nat Acad Sci U S A 2003;100:8407-8411
19. Rojas M, Xu J, Woods CR, et al: Bone marrow-derived mesenchymal stem cells in repair of the injured lung. Am J Respir Cell Mol Biol 2005;33:145-152
20. Ortiz LA, Dutreil M, Fattman C, et al: Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury. Proc Nat Acad Sci U S A 2007;104:11002-11007
21. Xu J, Woods CR, Mora AL, et al: Prevention of endotoxin-induced systemic response by bone marrow-derived mesenchymal stem cells in mice. Am J Physiol Lung Cell Mol Physiol 2007;293:L131-L141
22. Gupta N, Su X, Popov B, et al: Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol 2007;179:1859-1863
23. Xu J, Qu J, Cao L, et al: Mesenchymal stem cell-based angiopoietin-1 gene therapy for acute lung injury induced by lipopolysaccharide in mice. J Pathol 2008;214:472-481
24. Bruno S, Grange C, Deregibus MC, et al: Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol 2009;20:1053-1067
25. van Haaften T, Byrne R, Bonnet S, et al: Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med 2009;180:1131-1142
26. Aslam M, Baveja R, Liang OD, et al: Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease. Am J Resp Crit Care Med 2009;180:1122-1130
27. Frank JA, Briot R, Lee JW, et al: Physiological and biochemical markers of alveolar epithelial barrier dysfunction in perfused human lungs. Am J Physiol Lung Cell Mol Physiol 2007;293:L52-L59
28. Lee JW, Fang X, Gupta N, et al: Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Proc Nat Acad Sci U S A 2009;106:16357-16362
29. Ware LB, Matthay MA: Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am J Physiol Lung Cell Mol Physiol 2002;282:L924-L940